1/20. Maxillary giant cell granuloma, pheochromocytoma, and hyperparathyroidism without medullary thyroid carcinoma.We examined a young man who had a benign giant cell granuloma of the maxilla, which we subsequently diagnosed as a brown tumor associated with hyperparathyroidism. During surgery for the granuloma, the patient developed severe hypertension and was discovered to have an extra-adrenal pheochromocytoma. Oncogene and calcitonin testing for medullary carcinoma of the thyroid was negative. Therefore, despite the presence of both pheochromocytoma and hyperparathyroidism, we concluded that this patient did not have multiple endocrine neoplasia type 2a.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/20. Treatment of giant cell granuloma of the maxilla with intralesional injection of steroids.BACKGROUND: Giant cell granuloma is rare in the head and neck region and most commonly affects the maxilla and mandible. Although it is a benign disease process, it may be locally destructive. Surgery is the treatment currently recommended. Because of the location of the disease, surgery may be disfiguring. Because it is a benign process, less radical nonsurgical treatment alternatives are desirable. methods: A case report of a giant cell granuloma treated with steroid injections. RESULTS: After six weekly intralesional steroid injections, a giant cell granuloma of the maxilla became calcified and smaller. After a follow-up period of 2 years, there was no evidence of regrowth, and the bony osteolytic lesion had filled with bone. A review of the literature revealed two case reports of successful steroid injections with similar response. CONCLUSIONS: Steroid injections are a viable alternative in the treatment of giant cell granuloma, which may avoid surgery.- - - - - - - - - - ranking = 1.4keywords = giant (Clic here for more details about this article) |
3/20. Protruding giant cervical polyp in a young adolescent with a previous rhabdomyosarcoma.Giant cervical polyps are rare entities, with only 8 reported cases in the international literature (medline 1966-2002). Of these cases, only one has been described in the pediatric population. There has been no report of a giant cervical polyp occurring in the older, although early, adolescent period. The discovery of a giant cervical polyp in a young adolescent is a gynecological oddity. The immense size of giant cervical polyps, together with their menacing appearance and unusual presentation, can simulate a malignant neoplasm. Care must be taken in their diagnosis and management so that the patient's fertility is not compromised. We report on a young adolescent girl with a previous history of a rhabdomyosarcoma (RMS), who presented with a giant cervical polyp protruding from the vaginal introitus. The literature on this entity is reviewed.- - - - - - - - - - ranking = 1.6keywords = giant (Clic here for more details about this article) |
4/20. The central giant cell granuloma in childhood: clinical case report.This report reviews the literature involving the central giant cell granuloma. diagnosis and treatment are presented. The article reports the case of central giant cell granuloma, affecting the anterior region maxillary of a child, whom a conservative treatment, with cryotherapy, helped the preservation of anterior permanent teeth germs.- - - - - - - - - - ranking = 1.2keywords = giant (Clic here for more details about this article) |
5/20. Giant cell tumour (central giant cell lesion) of the maxilla.The giant cell tumour (GCT) is a benign, locally invasive lesion that accounts for about 20% of benign bone tumours. Approximately 2% of all GCTs arise in the head and neck region. Giant cell lesions in the craniofacial skeleton other than the jaws are uncommon; the majority of them occur in the sphenoid, ethmoid and temporal bones. GCT of the maxilla has seldom been described. We present the case of an 83-year-old patient with an advanced GCT of the left maxilla who underwent en bloc resection through maxillectomy. Reconstruction of the orbitary frame and maxilla was performed with autologous calvaria and a temporalis muscle pedicled flap. Our successful maxillary reconstruction based on the association between autologous calvarial bone sticks bent with titanium miniplates and a temporalis muscle pedicled flap allowed the involvement of only one donor area for both hard and soft tissues. At 1-year follow-up, our patient showed no evidence of recurrent GCT, with satisfactory aesthetic results.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
6/20. A central odontogenic fibroma exhibiting pleomorphic fibroblasts and numerous calcifications.A case of an odontogenic fibroma with unusual histopathological features is described. The tumour exhibited numerous, plump, stellate fibroblasts, similar to those found in the so-called giant cell fibroma. This finding has not been described previously in odontogenic fibromas. This case also exhibited an unusually large number of calcifications. Neither of these features should affect the biological behavior of this lesion.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
7/20. Giant-cell tumor of the maxilla. Report of a case.Giant-cell tumor of the jaw presents difficulty in diagnosis. It is rare in the head and neck regions and may resemble, clinically and histologically, other types of jaw lesion. However, histologic study may distinguish this lesion from a giant-cell granuloma, an osteogenic sarcoma, and most epulides. Adequate surgical excision with a long-term follow-up is the recommended treatment of choice.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
8/20. Management of a huge central giant cell granuloma of the maxilla.A case of a large central giant cell granuloma of the maxilla is presented. Its treatment by resection and reconstruction with a temporalis flap is described.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
9/20. Giant cementoblastoma simulating a peridental infection.A case of giant cementoblastoma of the maxilla in a young female is reported. An unusual painful swelling of the gingivolabial area led to an initial misdiagnosis of a peridental infection and consequently to inappropriate treatment.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
10/20. Ultrastructural study of intranuclear tubulo-filaments in a giant cell tumour of bone in a patient with Paget's disease.The intranuclear tubulo-filaments appearing in giant cells were studied ultrastructurally in a giant cell tumour of bone arising in a patient with Paget's disease. Serial sections have shown the presence of invaginating nuclear membrane around these apparent intranuclear tubulo-filaments, thus segregating these structures from the nuclear substance proper. Further sectioning showed clear continuity between these tubulo-filaments and the rest of the cytoplasmic contents. It is found that these apparent intranuclear tubules represent pseudo-inclusions rather than true intranuclear inclusions.- - - - - - - - - - ranking = 1.2keywords = giant (Clic here for more details about this article) |
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