1/15. A case of infantile neuroblastoma with intramucosal metastasis in a paranasal sinus.An 8-year-old boy with neuroblastoma of the right adrenal gland is reported. His initial treatment included chemotherapy and surgery, with complete response (CR) being achieved at the initial site. A metastatic lesion was found in the right maxillary sinus 32 months after his initial treatment. A mass in the right soft palate was detected and was clinically suspected of being a metastasis. The results of biopsy were negative and the differential diagnosis from the imaging studies of CT included odontogenic disease, fungal infection, paranasal sinus cyst or hematoma, and benign tumors. Open transantral biopsy was done under general anesthesia, revealing severe inflammation in the right maxillary sinus as well as bone erosion. The histopathological diagnosis was metastatic neuroblastoma from the adrenal lesion. The local field was irradiated with 20 Gy of linear accelerator (linac) radiation, then the local field was eradicated. Extensive skeletal metastases were subsequently found by bone scintigraphy. Despite further treatment his general condition deteriorated rapidly and he died 24 months after starting treatment. We review the previous reports and discuss metastasis to the sinuses.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/15. Clear cell adenocarcinoma of the maxillary sinus: a case report.A variety of salivary gland tumours histologically show the presence of clear cells. Clear cell adenocarcinoma of salivary glands (CCASG) is a distinct clinico-pathologic entity arising in the minor salivary glands of mainly the oral cavity in elderly women and having a low grade malignant potential. A case occurring in the maxillary sinus and extending to the nasal cavity is reported.- - - - - - - - - - ranking = 3keywords = gland (Clic here for more details about this article) |
3/15. A hybrid carcinoma of epithelial-myoepithelial carcinoma and adenoid cystic carcinoma in maxillary sinus.Hybrid carcinoma of the salivary gland is a very rare entity that has been described only in the parotid and palate. The occurrence of a hybrid carcinoma of maxillary sinus has not been reported. The diagnosis of hybrid carcinoma is important particularly when the components of tumor have different biologic behaviors. diagnosis and treatment require a high index of suspicion, especially when the tumor is an epithelial-myoepithelial carcinoma, pathological effort to look for a more aggressive accompanying tumor, and proper oncologic treatment. We describe a case of 26-yr-old woman with a hybrid carcinoma composed of epithelial-myoepithelial carcinoma with an adenoid cystic carcinoma component (cribriform pattern) in the right maxillary sinus with a brief review of the relevant literature.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
4/15. MALT lymphoma of the paranasal sinuses and the hard palate: report of two cases and review of the literature.Extra-nodal low-grade B-cell lymphomas arising in the gastrointestinal tract recapitulate the structure and features of mucosa-associated lymphoid tissue, called "MALT lymphomas." In the head and neck region except for the salivary glands the occurrence of this neoplasm is very rare. The authors report on two such cases of MALT lymphoma, one of the hard palate in a 71-year-old woman and the other of the paranasal sinuses in a 69-year-old woman with the history of chronic sinusitis. Such chronic inflammatory conditions can induce the development of MALT lymphoma. Clinical elaboration should include computerized tomography (CT) and magnetic resonance imaging (MRI) for the assessment of tumor extension, bone destruction, lymph node involvement and differentiation of mucosal thickening from tumor mass. biopsy for histopathological diagnosis is mandatory. Treatment should be surgery, irradiation or combined radio-chemotherapy depending on the stage of the disease.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
5/15. Oncocytic carcinoma of the maxillary sinus: a rare neoplasm.Oncocytic neoplasms are tumors composed of oncocytes (i.e., epithelial cells with a large cytoplasm that is rich in mitochondria). Most cases are benign and originate from the major salivary glands, while the minor salivary glands are rarely involved. Occurrence of oncocytic carcinoma (or malignant oncocytoma) within the sinonasal tract is an unusual event. We report a rare case of maxillary sinus oncocytic carcinoma occurring in a 45-year-old male. biopsy was consistent with an unspecified salivary gland neoplasm. The patient underwent total maxillectomy through a lateral rhinotomic approach; hard palate reconstruction with temporal myofascial flap was performed. Definitive histology was consistent with oncocytic carcinoma. Due to the local extension of the lesion, postoperative radiotherapy (60 Gy) was delivered. Three years after surgery, the patient is free from disease. A brief analysis of the literature was also accomplished in order to discuss treatment options and prognosis of this unusual neoplasm.- - - - - - - - - - ranking = 3keywords = gland (Clic here for more details about this article) |
6/15. tuberous sclerosis with primary meningioma of the maxillary antrum.Primary extracranial meningiomas are uncommon; they have been documented in the ear, skin, orbit, parapharyngeal space, parotid gland, mediastinum, and rarely the paranasal sinuses. tuberous sclerosis is an autosomal dominant neurocutaneous syndrome characterized by multiple connective tissue tumours. We report the first case of a tuberous sclerosis patient with a maxillary antral meningioma.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
7/15. maxillary sinus lymphoma: a consideration in the diagnosis of odontogenic pain.A patient with a known history of diffuse large cell histiocytic non-Hodgkin's lymphoma in the neck and left parotid gland presented with acute right maxillary odontogenic pain and swelling. Following endodontic treatment of the nonvital maxillary right second molar, minor masticatory discomfort persisted in the sextant but a dental etiology could not be established. Two months after the onset of symptoms, the right maxilla expanded uncontrollably and biopsy confirmed an antral lymphoma. The patient succumbed to the lymphoma and secondary complications 2 months later.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
8/15. Adenoid cystic carcinoma: an unusual neurosurgical entity.Adenoid cystic carcinoma, or cylindroma, usually presents in the salivary glands or in the upper respiratory passages. We report an unusual case of adenoid cystic carcinoma in a 45-year-old woman who presented with a three-year history of progressive right trigeminal sensory palsy, most pronounced in the second division. There was, in addition, a right trigeminal motor palsy and a partial right 6th nerve palsy. CT scanning showed only a small soft tissue mass spanning an enlarged right foramen ovale. Solid adenoid cystic carcinoma was resected from Meckel's cave via a middle cranial fossa approach. A subsequent biopsy of the right maxillary antral mucosa found tumor tissue. We concluded that the tumor originated in the maxillary antrum and spread posteriorly along the infraorbital nerve to enlarge in the foramen ovale. radiation to a total of 5,000 cGy was given. At 22 months there was neither radiographic nor clinical evidence of recurrence. At 30 months, the development of unsteady gait signalled the presence of recurrent tumor extending backwards from Meckel's cave into the right cerebello-pontine angle.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
9/15. Sinonasal teratocarcinosarcoma: an unusual neoplasm.Sinonasal teratocarcinosarcoma (SNTCS) is a very unusual and aggressive neoplasm characterized by the combination of malignant teratoma and carcinosarcoma features, of which less than forty cases have been reported in the literature. We report on a 75-year-old man with SNTCS that involved the left ethmoid, maxillary and sphenoidal sinuses. The tumor showed a complex histological pattern with mature and immature glands, benign squamous and malignant poorly differentiated epithelia, as well as neuroblastoma-like tissue and sarcoma component with rhabdomyoblastic differentiation. This peculiar blend of tissue types makes the diagnosis of this entity a difficult challenge, especially in small biopsies or in tumors only partially removed. This tumor must be differentiated from several types of carcinomas, esthesioneuroblastoma, craniopharyngioma, malignant mixed tumor of salivary gland type and germ cell tumors. The present case represents, to our knowledge, the third SNTCS described in the european literature.- - - - - - - - - - ranking = 2keywords = gland (Clic here for more details about this article) |
10/15. bone marrow metastases from small cell cancer of the head and neck.BACKGROUND. Primary small cell carcinoma of the head and neck is rare. Although the larynx is the most prevalent site of head and neck small cell carcinoma (SCC), this report will concentrate on SCC of the major salivary glands and paranasal sinuses. In all, 33 cases of paranasal sinus and 43 cases of major salivary gland SCC have been reported in the literature. methods. We report two patients, one with submandibular gland SCC and the other with maxillary sinus SCC. A literature review of all known paranasal sinus and major salivary gland SCC with inclusion of data from these two new cases is undertaken. Discussion of all past and present cases concentrates on sites of metastasis, treatment, and survival. RESULTS. Paranasal sinus SCCs predominantly arise from the nasal cavity, whereas the parotid gland is the primary site in three fourths of major salivary gland SCCs. One half of major salivary gland and three fourths of paranasal sinus SCCs have only local disease at presentation. Both patients in this report developed bone marrow metastases, a feature heretofore not observed in SCC from these primary sites. The patient with maxillary sinus SCC developed the syndrome of inappropriate antidiuretic hormone (SIADH). CONCLUSION. The paranasal sinus and major salivary glands are rare primary sites for SCCs. Long-term survival with local therapy in patients with local disease can occur, but in patients with metastatic disease survival mirrors metastatic pulmonary SCC.- - - - - - - - - - ranking = 8keywords = gland (Clic here for more details about this article) |
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