1/8. Pustular miliaria rubra: a specific cutaneous finding of type I pseudohypoaldosteronism.Type I pseudohypoaldosteronism, an autosomal recessive, life-threatening disorder of mineralocorticoid resistance leads to excessive loss of sodium chloride through eccrine and other secretions. Recurrent episodes of pustular miliaria rubra are associated with salt-losing crises and clear spontaneously with stabilization. inflammation of and around the damaged eccrine glands has been attributed to the deleterious effects of excessive eccrine gland salt exposure.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/8. Basaloid follicular hamartoma with eruptive milia and hypohidrosis: is there a pathogenic relationship ?We report a sporadic case of eruptive milia with histopathological features of basaloid follicular hamartoma which developed in an 8 year-old Japanese girl. Multiple milia and comedo-like eruptions were present at birth and gradually increased in number and spread over the extremities. Histopathologically, keratotic cysts with trichilemmal keratinization and features of basaloid follicular hamartoma were observed without any histological findings of basal cell epithelioma or trichoepithelioma. Reduced sweating was observed after iontophoretically applied acetylcholine on the forearm. nevus of ota and thyroid goiter were complications.- - - - - - - - - - ranking = 166.80340113301keywords = sweat (Clic here for more details about this article) |
3/8. miliaria crystallina in an intensive care setting.Drop-like, transient blisters of miliaria crystallina may develop with focal intensity of heat within the skin, such as occurs in tropical climates or during febrile episodes. miliaria crystallina develops due to a transient poral closure of the sweat duct opening, resulting in obstruction of free flow of eccrine sweat and retention in a vesicle below the skin surface. Dual cholinergic and adrenergic sweat gland innervation is influenced by a variety of medications used in intensive care patients. We present two febrile intensive care patients in whom enhanced alpha-adrenergic stimulation of sweat gland myoepithelia may have led to miliaria crystallina.- - - - - - - - - - ranking = 1357.0301724763keywords = sweat gland, sweat, gland (Clic here for more details about this article) |
4/8. Rare skin disorder complicating doxorubicin therapy: miliaria crystallina.miliaria is a self-resolving disorder of the eccrine sweat glands caused by blockage of the sweat ducts resulting in the leakage of eccrine sweat into epidermis or dermis. In addition to known predisposing factors such as heat, humidity, and fever, a few drugs (eg, isotretinoin and bethanechol) can also precipitate miliaria. We present here a case of miliaria crystallina that developed in a 65-year-old patient on the fifth day after administration of doxorubicin for multiple myeloma in the absence of known predisposing factors. miliaria crystallina resolved in 3 days without any complications. To our knowledge, this is the first reported case of doxorubicin-induced miliaria crystallina.- - - - - - - - - - ranking = 845.31848737118keywords = sweat gland, sweat, gland (Clic here for more details about this article) |
5/8. Congenital miliaria crystallina.miliaria crystallina is characterized by intracorneal or subcorneal, 1 to 2 mm, clear, noninflammatory vesicles that typically appear in crops after a severe sunburn or during a febrile illness. They frequently occur in neonates, most likely due to lack of maturation of the sweat duct during the first few days following birth, but are rarely present at delivery. We describe here a patient with extensive miliaria crystallina that was present at birth and review possible theories of the pathogenesis of these lesions.- - - - - - - - - - ranking = 166.80340113301keywords = sweat (Clic here for more details about this article) |
6/8. Giant centrifugal miliaria profunda.A 4-month-old developed rapidly enlarging, white plaques up to several centimeters in diameter in areas where occlusive tape had been applied, almost all on the sites of venous or arterial punctures. microscopy demonstrated the features of miliaria profunda, with sweat duct occlusion and evidence of extravasation of sweat into the dermis. This clinical entity has not been described previously, and we suggest the name giant centrifugal miliaria profunda.- - - - - - - - - - ranking = 333.60680226602keywords = sweat (Clic here for more details about this article) |
7/8. Deletion 3q273qter in an infant with mild dysmorphism, parietal meningocele, and neonatal miliaria rubra-like lesions. Deletion 3q27 3qter in an infant is described. A chromosomal abnormality was suspected because of minor facial dysmorphism and closed parietal meningocele. On the first day of life, a large exudative inflammation appeared on the skin of her back, which completely resolved after 1 week. biopsy showed dilated sweat gland openings resembling miliaria rubra, which has not been previously reported in this age group. It is unclear if the skin change was due to the chromosomal abnormality. The meningocele was repaired at age 8 months. At age 20 months, slight neurodevelopmental delay was evident, the main features being hypertonicity and inability to walk without support. The patient has two healthy sisters, and prometaphase chromosome studies in both parents were normal. This infant represents the first example of del3q27 3qter and the first reported association of meningocele with an abnormality of chromosome 3.- - - - - - - - - - ranking = 511.71168510516keywords = sweat gland, sweat, gland (Clic here for more details about this article) |
8/8. Symptomatic hyponatremia during prolonged exercise in heat.Although hyponatremia (HN) has been reported among endurance athletes, its etiology often remains uncertain and of great interest to clinicians and physiologists. This case report presents physiologic evidence regarding the etiology and development of HN during exercise in the heat. A 21-yr-old male volunteer (K.G.) unexpectedly experienced symptomatic HN during a research investigation that involved controlled sodium (Na ) intake (137 mEq Na .d-1 for 7d) and exercise-heat acclimation (41 degrees C; 30 min.h-1, 8 h.d-1 for 10 d). Fluid balance, physiologic variables, and hematologic/hormone data were measured before and after the HN episode, with similar measurements recorded for nine unaffected volunteers. The results indicated: 1) HN was verified in K.G. (plasma Na < 130 mEq.l-1) after only 4 h of mild, intermittent exercise in heat; 2) K.G.'s heart rate, rectal temperature, blood pressure, and Na losses in sweat and urine were < or = control subjects at all times; 3) between hours 4-7, an inappropriately large release of vasopressin coincided with a decrease of urine volume to 0 ml.h-1. It was concluded that a large intake (10.3 l.7h-1) and retention (2.77 l.7h-1) of water and a "low normal" initial plasma Na (134 mEq.l-1) were primary factors in the development of HN in K.G., whereas Na losses in sweat and urine were normal and served only to exacerbate HN.- - - - - - - - - - ranking = 333.60680226602keywords = sweat (Clic here for more details about this article) |