Cases reported "Mouth Diseases"

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1/335. Verruciform xanthoma and concomitant lichen planus of the oral mucosa. A report of three cases.

    Verruciform xanthomas are benign muco-cutaneous lesions of unknown aetiology. They have a papillated surface and histologically they are characterised by the presence of foam cells in connective tissue papillae between elongated parakeratinised epithelial rete ridges. Three cases are reported in which oral mucosal verruciform xanthoma and oral mucosal lichen planus occurred concomitantly.
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keywords = mucosa
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2/335. Oral wart associated with human papillomavirus type 2.

    More than 100 human papillomavirus (HPV) types have been identified to date. Of these, 24 types have been described as being associated with oral lesions. HPV-2 has been frequently associated with skin lesions, but the reports of oral lesions as features of mucosal infection are limited. A biopsy specimen of an oral wart on the right palate was taken from a 48-year-old man and examined for the presence of HPV The sections showed papillary growth of the epithelium with hyperkeratosis and parakeratosis, and koilocytotic changes of the cells located in the upper layers of the oral squamous cell epithelium. These histological features corresponded well to those of verruca vulgaris on the skin. Immunohistochemically, papillomavirus genus-specific capsid antigen was detected in most of the koilocytotic cells. In addition, Southern blot hybridization analysis revealed that the lesion harbored HPV-2 dna. in situ hybridization with a biotinylated HPV-2 dna probe clearly demonstrated viral dna in the nuclei of squamous cells, which were located in a deeper layer of the epithelium than viral antigen-positive cells.
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ranking = 0.16666666666667
keywords = mucosa
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3/335. oral manifestations of idiopathic lenticular mucocutaneous pigmentation (Laugier-Hunziker syndrome): a clinical, histopathological and ultrastructural review of 12 cases.

    OBJECTIVE: To present a clinical, histopathological and ultrastructural study on a group of patients affected by idiopathic mucocutaneous pigmentation (Laugier-Hunziker syndrome: LHS). MATERIALS AND methods: Twelve patients were investigated: clinical examination, laboratory tests, and X-ray studies together with light microscopy and electron microscopy were performed in order to diagnose LHS. RESULTS: All cases showed acquired, benign, macular hyperpigmentation of buccal mucosa lips and nails. Histologically, pigmentations are due to an accumulation of melanin in the basal layer keratinocytes and an increase in the number of melanophages in the submucosa and/or papillary dermis. Ultrastructurally there were increased numbers of normal-appearing melanosomes in keratinocytes of the lower epithelium. No evidence of malignant changes were detected. CONCLUSIONS: The importance of this condition relates to it being included in the differential diagnoses of pigmentary disorders of the oral mucosa with associated nail involvement. It is important to recognize this acquired benign disorder to avoid unnecessary investigations and treatments.
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ranking = 0.5
keywords = mucosa
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4/335. Laugier-Hunziker syndrome: case report and treatment with the Q-switched Nd-Yag laser.

    We report the case of a 46-year-old Caucasian female presenting with mucocutaneous pigmentation on the lips, oral mucosa, hands, feet and nails, as well as on a psoriatic plaque. She was successfully treated with Q-switched Nd-Yag laser, with double frequency, for both the mucosal and cutaneous lesions.
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ranking = 0.33333333333333
keywords = mucosa
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5/335. oral manifestations as a hallmark of malignant acanthosis nigricans.

    We present a case of malignant acanthosis nigricans (AN) that initially manifested in the oral cavity. In the present report, the patient had typical clinical and histological findings of oral and esophageal AN, with subtle skin changes, associated with a gallbladder adenocarcinoma. The importance of the clinical oral examination is emphasized because the recognition of oral lesions led to the diagnosis of AN and to the following detection of the internal malignancy. Since the tumours associated with AN are highly malignant, it is of the utmost importance to recognize the skin and mucous membrane changes in adults.
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ranking = 0.40437193896959
keywords = mucous membrane, membrane
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6/335. Bilateral congenital oral mucous extravasation cysts.

    This report documents the bilateral presentation of oral mucous extravasation cysts on the left mucobuccal fold and right buccal mucosa of a neonate. The lesions were noted at birth and subsequently enlarged to the point that they interfered with eating. The left lesion ruptured but persisted as an exophytic fibrotic mass. Both lesions were surgically removed at eight months and the diagnosis was confirmed by histopathologic examination. Post-operative follow-up after nine months shows no recurrence. The presentation and diagnostic considerations are discussed.
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ranking = 0.16666666666667
keywords = mucosa
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7/335. Recurrent buccal space abscesses: a complication of Crohn's disease.

    Oral features of Crohn's disease include ulcerations, lip fissuring, cobblestone plaques, and mucosal tags. We report the case of a 16-year old male patient with a 3-month history of abdominal pain, diarrhea, and oral ulceration. Clinical examinations revealed established intestinal lesions, a marked cobblestone appearance in the oral cavity, and an unusual pattern of presentation not previously reported in the literature: persistent, recurrent buccal space abscesses.
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ranking = 0.16666666666667
keywords = mucosa
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8/335. Oral nodular excrescences in epidermolysis bullosa.

    Two brothers are reported with what appears to be a recessive and dystrophic type of epidermolysis bullosa. The oral lesions seen in these patients consisted of small fibrous nodules that were liberally distributed on the bound-down mucosa. These lesions have not been previously reported. One of the offspring of these patients, who was not affected by epidermolysis bullosa, was missing a large number of teeth.
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ranking = 0.16666666666667
keywords = mucosa
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9/335. Hereditary hemorrhagic telangiectasia with gingival lesion. review and case reports.

    A case of hereditary, hemorrhagic telangiectasia is described which has been under observation for more than 8 years. The clinical findings are discussed; light microscopic and electron microscopic findings as well as current research for a causative mechanism and recommended therapy are reviewed. The patient exhibited gingival telangiectatic participation. Another, even more severe case of this disease showed repeated, severe hemorrhage from mucosal lesions in the region of the incisive papilla, severe internal bleeding from the nasal mucosa and the gut and several punctate gingival telangiectases. The occurance of gingival lesions may not be as rare as thought. Such lesions may simply be rather inconspicuous.
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ranking = 0.33333333333333
keywords = mucosa
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10/335. Atypical herpes simplex can mimic a flare of disease activity in patients with pemphigus vulgaris.

    We present a 69-year-old white woman with pemphigus vulgaris limited to the oral mucosa who presented with oral pain and difficulty swallowing of 2 days duration, followed by multiple irregular ulcers arising from normal mucosa with no grouping of individual lesions--herpes simplex should be considered in the differential diagnosis of lesions that appear suddenly in patients with PV, particularly if the lesions fail to respond to an increased dose of corticosteroids.
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ranking = 0.33333333333333
keywords = mucosa
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