1/5. Oral and dental manifestations of vitamin d-dependent rickets type I: report of a pediatric case.vitamin d-dependent rickets type I (VDDRI) represents an autosomal recessive hereditary defect in vitamin d metabolism. patients with VDDRI have mutations of chromosome 12 that affect the gene for the enzyme 1-alpha-hydroxylase, resulting in decreased levels of 1,25(OH)(2) vitamin d. Clinical features include growth failure, hypotonia, weakness, rachitic rosary, convulsions, tetany, open fontanels, and pathologic fractures. The oral and dental manifestations of VDDRI have not been described. Here we present the case of a 10-year-old girl affected by VDDRI, as established by the combination of clinical and radiographic findings, family history, and laboratory values. Dental examination revealed markedly hypoplastic, yellowish-to-brownish enamel in all permanent teeth, malocclusion, and chronic periodontal disease. Large quadrangular pulp chambers and short roots were evident in dental radiographs. light microscopic and ultrastructural examination showed abnormalities of dental hard tissues, affecting both enamel and dentin. The differential diagnosis and treatment of VDDRI are discussed.- - - - - - - - - - ranking = 1keywords = periodontal disease (Clic here for more details about this article) |
2/5. Oral manifestation of immunoproliferative small intestinal disease. A case report.A patient with a previous medical history of immunoproliferative small intestinal disease (IPSID) presented with persistent red and ulcerated lesions on her attached gingiva. Despite the obvious long standing gingival inflammation, minimal destruction of alveolar bone had occurred. Following failure of the tissues to respond to routine periodontal therapy, a gingival biopsy was taken. Histological assessment of the specimen revealed several features in common with the intestinal lesions seen in IPSID. In particular, a large plasma cell infiltrate subjacent to the gingival epithelium was noted. There was a marked loss of normal connective tissue morphology and evidence of epithelial degeneration. Treatment has since consisted of palliative measures only. While this is a relatively rare condition, it (as well as other disorders of the immune system) provides a useful insight into the role that the immune system plays in the inflammatory periodontal diseases.- - - - - - - - - - ranking = 1keywords = periodontal disease (Clic here for more details about this article) |
3/5. oral manifestations of bone marrow transplantation.Bone marrow protection by transplantation permits the administration of large doses of antitumor drugs and radiation. Severe oral complications occur in about 70% of patients who have had allogeneic bone marrow transplants and to a lesser degree in patients who have had autologous and syngeneic transplants. Oral complications consist of mucositis, salivary gland dysfunction, loss of resiliency of perioral tissues, periodontal disease, and caries. Pre- and post-transplant oral care aimed at plaque control, control of dental pathology, and hydration of oral tissues are important factors in support therapy of bone marrow transplant patients.- - - - - - - - - - ranking = 1keywords = periodontal disease (Clic here for more details about this article) |
4/5. Progressive systemic sclerosis in a child: case report.A case of pediatric progressive systemic sclerosis is reported and a literature review concerning medical and dental aspects of this condition is provided. Systemic features include sclerodactyly, Raynaud's phenomenon, telangiectasia, calcinosis, myositis, arthritis, tenosynovitis, renal failure, esophageal hypomotility, pulmonary fibrosis and heart failure. oral manifestations include reduced interincisal distance, xerostomia, telangiectasia, increased periodontal ligament width, osseous resorption of the mandible, periodontal disease, and increased decayed, missing, and filled teeth (DMFT). The prognosis is difficult to predict because spontaneous remission has been documented, but death may result from extensive visceral involvement (heart, kidney, and lung).- - - - - - - - - - ranking = 1keywords = periodontal disease (Clic here for more details about this article) |
5/5. cytomegalovirus infection presenting as acute periodontal infection in a patient infected with the human immunodeficiency virus.During childhood, many people acquire primary infection with cytomegalovirus (CMV), one of the herpes viruses. If they later become immunosuppressed, such as occurs with human immunodeficiency virus (hiv) infection, CMV is likely to become reactivated. Severe disease caused by CMV is life-threatening in the hiv-infected population. CMV retinitis, gastritis, colitis, pneumonia, encephalitis and hepatitis have all been reported, but oral lesions due to infection with CMV are rarely reported. We report a case of oral CMV infection which at first was clinically indistinguishable from hiv-associated periodontal disease.- - - - - - - - - - ranking = 1keywords = periodontal disease (Clic here for more details about this article) |