1/15. melanoma of the face and mouth in nigeria. A review and comment on three cases.The absolute incidence of melanoma at all sites in blacks is higher than is commonly credited. There is a shift in site incidence to less pigmented areas including the mucosae but oral melanoma is still rarely reported in Africans. An unusual case of facial melanoma arising in a childhood naevus, and two oral melanomas, all in Nigerians, are described. The salient clinical features and the treatment of these cases are discussed, and the possible relationship between pigmented patches and melanomas in the mouths of blacks is examined.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |
2/15. Multiple intraoral melanoacanthomas: a case report with unusual findings.Melanoacanthoma is a rare, benign, mucocutaneous pigmented lesion characterized by colonization of acanthotic epithelium by dendritic melanocytes.(1,2) The most common intraoral sites are the buccal(3,4) and masticatory mucosa subject to chronic irritation.(1,5) The pathogenesis of oral melanoacanthoma remains uncertain, although its clinical behavior is suggestive of a reactive cause.(3,4,6,7) The clinical appearance of melanoacanthoma is nondiagnostic, and biopsy is mandatory.(2,3,5,6,8) The lesion, however, requires no treatment(5) and elimination of local irritants as well as periodic observation are the recommended interventions.(1,8) We describe a 39-year-old black patient with a recently reported palatal melanoacanthoma who developed additional lesions in other intraoral sites approximately 3 months after the initial lesion was biopsied. This article also documents the reactive and reversible nature of intraoral melanoacanthoma in a rare case of multiple lesions.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
3/15. Intraoral perineurioma: report of a case with a review of the literature.Perineurioma is a rare benign peripheral nerve sheath tumour that occurs as an intraneural or extraneural form. To the best of our knowledge, this is the second reported case of an intraoral submucosal extraneural perineurioma. The tumour was symptomless, measured 2 cm in diameter and occurred in the nasolabial fold of a 46-year-old black female. awareness of the occurrence of this neoplasm in the oral cavity is important to promote detection and differentiation from other benign spindle tumours, which occur intraorally. All reported cases of perineurioma have been benign and cure is effected by localized surgical excision.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
4/15. Oral metastasis of breast carcinoma diagnosed by fine needle aspiration cytology. A case report.BACKGROUND: Fine needle aspiration cytology (FNAC) is an important technique in the diagnosis of oral and maxillofacial conditions. The purpose of the present paper is to report a case of oral metastasis of breast carcinoma diagnosed by FNAC. CASE: A 45-year-old, black woman was referred for evaluation of symptomatic swelling in the left mandible. The medical history revealed that the patient had undergone extensive surgery to remove a lobular carcinoma. She had finished chemotherapy treatment about 5 months earlier. Due to the main diagnostic considerations of metastatic and inflammatory disease, FNAC was performed. The cytologic picture was consistent with a metastatic glandular neoplasm. CONCLUSION: FNAC is a safe, reliable, cost-effective and easy procedure and sometimes eliminates the need for open biopsy.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
5/15. Oral melanoacanthosis (melanoachantoma): report of a case and review of the literature.Oral melanoacanthosis (MA) is a rare pigmented mucosal lesion that is considered the counterpart of cutaneous melanoacanthoma. Microscopically the superficial epithelium shows mild to moderate acanthosis, spongiosis and prominent dendritic melanin producing melanocytes, which are present throughout the spinous keratinocytes. Reported cases show predilection for black females and the most common locations in decreasing frequency are buccal mucosa, lip, palate and gingiva. Although its pathogenesis remains uncertain, its clinical behavior is suggestive of a reactive origin. The clinical appearance of oral MA is non diagnostic and therefore biopsy is mandatory to differentiate from other melanocytic lesions, including melanoma.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
6/15. Oral melanoacanthoma: a case report, a review of the literature, and a new treatment option.OBJECTIVES: Oral melanoacanthoma is a rare condition that presents as a pigmented, painful lesion, most commonly on the buccal mucosa. argon plasma coagulation is a new treatment option for benign oral lesions and is hypothesized to be efficacious for this rare mucosal disorder. methods: Treatment of a case and a review of the English-language literature were performed. RESULTS: One patient received a diagnosis of oral melanoacanthoma, and argon plasma coagulation treatment resulted in ablation of the lesion with excellent mucosal healing. A review of the literature demonstrated that this lesion is most commonly associated with black (90.9%), adult female (69.7%) patients and is most commonly located on the buccal mucosa (64.7%). CONCLUSIONS: Oral melanoacanthoma is a rare, benign mucosal lesion that may require surgical intervention for symptomatic relief. argon plasma coagulation is a relatively safe and effective means of treating this lesion. argon plasma coagulation treatment may be expanded to include other benign, superficial lesions of the oral mucosa.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
7/15. Apocrine carcinoma in the parotid gland and in the submandibular region.The objectives of this paper are to report a case of apocrine carcinoma and the discussion of aspects related to its diagnosis, treatment, and prognosis. Carcinomas with apocrine differentiation not related to extramammary Paget's disease, ductal breast carcinoma, Moll's glands adenocarcinoma and ceruminous glands carcinoma are very uncommon tumors. We report a case of a 51-year-old black woman who developed apocrine carcinoma lesions in the head and neck region. Two lesions involved her left parotid gland (first tumor and local recurrence), and other involved her submandibular skin. The microscopic aspects were as follows: infiltrative glandular epithelial neoplasm with moderate cellular and nuclear pleomorphism; neoplasic cells with polygonal or circular shape, large nuclei and eosinophilic and granular cytoplasm. The apical decapitation secretion was viewed in a large number of intra-cystic tumor cells. Moreover, we found areas with comedo-necrosis or PAS positive staining (with or without diastase). Based on cutaneous apocrine carcinoma compatibility of the microscopic aspects, we concluded that the tumor in the submandibular skin was probably the primary neoplasm. The patient was treated by surgical excisions, and no evidence of recurrent or metastatic disease has been seen after a follow-up period of 12 months.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
8/15. Oral melanoacanthoma with prominent spongiotic intraepithelial vesicles.Oral melanoacanthoma is a rarely-reported, benign pigmented lesion of oral mucosa. Spongiosis was only recently mentioned as a light-microscopical finding occasionally seen in oral melanoacanthoma, and the formation of spongiotic intraepithelial vesicles to our knowledge has never been reported. The authors discuss a case of a 34-year-old, black woman who acutely developed extensive hyperpigmented oral lesions which on the biopsy showed both intraepithelial dendritic melanocytes and severe spongiosis forming intraepithelial vesicles. These lesions resolved spontaneously in a few months which led the authors to believe that the term melanoacanthoma, implying that it is a tumor, is a misnomer. This report supports findings of other investigators who consider oral melanoacanthoma to be a mucositis with unusual proliferation of dendritic melanocytes in the epidermis.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
9/15. Squamous cell carcinoma of the oral cavity, pharynx, and larynx in young adults.Thirty-nine adults (34 male, 5 female) age 40 or under with squamous cell carcinoma of the head and neck (excluding nasopharyngeal carcinoma) were seen at the Baylor College of medicine affiliated hospitals from 1964 to 1983. The average age of the patients was 36.3 years and they were nearly uniformly heavy smokers and drinkers. Twenty-six of the 39 patients were black. Lesions of the oral cavity and oropharynx were most frequent, followed by laryngeal lesions. Four patients presented with second primary tumors, and one patient had three separate lesions. Of the 39 patients, only 8 had cancers small enough to be considered curable by radiotherapy or organ-sparing surgery. The remainder of the patients required radical surgery (26), were considered incurable at the time of presentation (8), or refused treatment (3). Also noted was a relatively high incidence of prior trauma (gunshot wounds, laparotomies for trauma). Of 30 patients available for follow-up more than one year after treatment, 19 have died of their tumors. Only one patient had a documented immune disorder (systemic lupus). In contrast to previous authors, we conclude that the development of squamous cell carcinoma at a young age can be related to heavy smoking and drinking and that the poor survival in many patients is due to self-neglect and failure to seek medical care early in the course of the disease.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
10/15. Kaposi's sarcoma of the oral cavity. A case report.A case of Kaposi's sarcoma of the oral cavity in a 54-year-old black man is reported. The possible association with acquired immune deficiency syndrome is emphasized and the diagnosis, treatment and prognosis of oral Kaposi's sarcoma are discussed.- - - - - - - - - - ranking = 0.5keywords = black (Clic here for more details about this article) |
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