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1/267. Coronary artery aneurysms in a young adult: a case of sudden death. A late sequelae of Kawasaki disease?

    The case concerns the sudden death of a 21-year-old male during a soccer game. The autopsy revealed large, calcified saccular aneurysms at the origins of both the left anterior descending and the right coronary arteries. Histologically, the wall of the aneurysms was thin and composed of an internal fibro-calcified layer and an external thin tunica media. There was no evidence of active inflammation. The autopsy findings and a detailed medical history support the diagnosis of a late fatal sequela of Kawasaki disease.
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ranking = 1
keywords = coronary
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2/267. Coronary stent deployment in a young adult with Kawasaki disease and recurrent myocardial infarction.

    A 19-year-old man developed a huge coronary aneurysm and stenosis in the right coronary artery as a sequela of Kawasaki disease (KD) that resulted in recurrent episodes of myocardial infarction. Coronary ischemic events were successfully prevented after balloon angioplasty followed by coronary stent implantation into the stenotic lesion. The stent deployment may have an advantage compared with balloon angioplasty and other new devices for the treatment for patients with KD showing stenotic lesions without dense calcification.
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ranking = 3
keywords = coronary
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3/267. Recurrent Kawasaki disease.

    Kawasaki disease (mucocutaneous lymph node syndrome) is a disease of unknown aetiology characterised by vasculitis which may affect the coronary arteries. Young children are most commonly affected although the disease has been described in adults. We report a case of recurrent Kawasaki disease which presented to an oral medicine clinic, where early recognition prompted appropriate management.
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ranking = 1
keywords = coronary
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4/267. Stenting of coronary artery stenosis in Kawasaki disease.

    Coronary artery lesions can develop in Kawaski disease as a major complication, and result in aneurysm formation and stenosis. Reported is the evolution of important coronary artery stenosis in a pediatric patient managed with an endovascular stent.
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ranking = 5
keywords = coronary
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5/267. Early reactive neutrophil changes in an infant with Kawasaki syndrome.

    An infant with Kawasaki syndrome presenting with fever, rash, and a high percentage of neutrophils with toxic granulation is reported. The peripheral blood smears of the patient showed a high proportion of neutrophils with marked vacuoles and toxic granulations. The reactive changes in neutrophils could be helpful in the early detection of the disease, especially in infants younger than 6 months of age who are at high risk for development of coronary artery disease.
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ranking = 1
keywords = coronary
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6/267. A rare case: surviving acute left main coronary artery occlusion in Kawasaki's disease.

    We present a case of cardiogenic shock due to acute thrombotic occlusion of the left main coronary artery in Kawasaki's aneurysmal coronary artery disease. The patient was treated with PTCA as a bridge to CABG. Because of a persistent low-output syndrome, orthotopic heart transplantation was successfully performed three days later. The patient is alive and well one year after the event.
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ranking = 6
keywords = coronary
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7/267. Surgical angioplasty of the left main coronary artery in non-atherosclerotic lesions.

    Surgical angioplasty of the left main coronary artery confers several advantages over conventional bypass surgery: unrestricted forward flow is provided to the entire coronary bed and graft material is spared. The literature contains many reports of surgical angioplasty of atherosclerotic stenoses. The technique is described in five patients with non-atherosclerotic disease of the left main coronary artery: three children (a 7 year old girl who had undergone an arterial switch operation shortly after birth; a 9 year old boy with congenital supravalvar aortic stenosis; and a 10 year old girl with Kawasaki's disease) and two adults (a 51 year old woman with post-radiation stenosis; a 53 year old man with acute dissection). All patients had an uneventful recovery and are free from symptoms with a widely open left main trunk. Although technical difficulties are increased in these patients, excellent results can be achieved with this approach.
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ranking = 7
keywords = coronary
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8/267. tissue plasminogen activator in pediatric myocardial infarction.

    Children rarely present to emergency physicians during an acute myocardial infarction. However, this may occur in the setting of Kawasaki disease with thrombosed coronary aneurysms. We present the first case in which intravenous tissue plasminogen activator was used to successfully treat a 7-year-old child having an acute myocardial infarction caused by a thrombosed coronary aneurysm.
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ranking = 2
keywords = coronary
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9/267. ticlopidine plus aspirin for coronary thrombosis in Kawasaki disease.

    Selective inhibitors of the adenosine 5'-diphosphate pathway of platelet activation have been used rarely in children in the united states. We report the successful use of ticlopidine, together with aspirin, in a 7-month-old infant with Kawasaki disease complicated by a thrombus in a giant coronary aneurysm that failed to resolve with thrombolytic therapy. Kawasaki disease, coronary aneurysms, antithrombotic therapy, ticlopidine, children.
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ranking = 6
keywords = coronary
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10/267. Successful recovery after ventricular fibrillation in a patient with Kawasaki disease.

    Kawasaki disease (KD) is an uncommon cause of sudden death in young adults in europe. Angiographically, the disease is characterized by coronary artery aneurysms which can be fully obstructed by acute thrombosis or by progression of the disease. If diagnosis of KD is made, immediate investigation should be made to determine whether ischemia is occurring and if so, to establish optimal time for revascularisation or cardiac transplantation. We describe an 18-year-old Caucasian male who was not previously known to have KD and who suffered from an acute myocardial infarction complicated by ventricular fibrillation, caused by acute thrombosis of a coronary artery aneurysm.
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ranking = 2
keywords = coronary
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