1/8. Two cases of orbital infarction syndrome.Orbital infarction syndrome is defined as ischemia of all intraorbital and intraocular structures. It is a rare disease caused by rich anastomotic vascularization of the orbit. It can occur secondary to different conditions, such as, acute perfusion failure, systemic vasculitis, orbital cellulitis and vasculitis. It results in orbital and ocular pain, total ophthalmoplegia, anterior and posterior segment ischemia, and acute blindness. We report here upon two cases of orbital infarction with similar presentations but with different causes, namely, mucormycosis and as a postoperative complication of intracranial aneurysm, discuss the possible mechanisms of orbital infarction, and present a review of the literature on the topic. The prompt recognition of clinical pictures and rapid diagnosis is essential for the early treatment of orbital infarction, since its progression is very rapid and it can be even fatal.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/8. Cutaneous zygomycosis: a case report and review of Japanese reports.A 69-year-old man, a carpenter with idiopathic thrombopenic purpura and interstitial pneumonia, was treated with steroid pulse therapy and antibiotics. On the seventh day of steroid therapy, a conglomeration of papules, vesicles and pustules appeared in an area of the left buttock in contact with his napkin. In a Parker KOH specimen of the crust of the lesion, many non-septate hyphae were seen, and culture of material obtained by biopsy yielded rhizopus microsporus var. microsporus. ketoconazole cream was applied topically for 1 week, and the exanthema healed. After the third month of inpatient treatment, the patient's overall condition had returned to normal, and he was discharged. Cutaneous zygomycosis is a rare disease, and only 19 cases have been reported in japan. Its characteristics, as reported in these cases, have been collected and collated.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
3/8. Successful treatment of rhinocerebral mucormycosis with liposomal amphotericin b and surgery in two diabetic patients with renal dysfunction.The zygomycetes are a class of fungi that can cause a variety of infections in humans. Rhinocerebral mucormycosis is a rare disease and usually affects diabetic or immunosuppressed patients. The disease progresses rapidly and is usually fatal despite aggressive surgical and medical therapy. We report the management of two cases of rhino-sinusal and orbital mucormycosis in diabetic patients on treatment with corticosteroids, and mild renal impairment, successfully treated with a combination of aggressive surgical debridement and liposomal amphotericin b.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
4/8. Pulmonary mucormycosis: the first case with preoperative diagnosis and successful surgical treatment in taiwan.Pulmonarycosis is a rare disease, which refers to an infection by fungi belonging to the order mucorales. This organism usually invades the skin, nose mouth, paranasal sinus, gastrointestinal tract, lung, brain, eyes and so forth. It usually occurs in patients with diabetes mellitus, hematological malignancy or other immunocompromised states. Until recently, this disease was rarely diagnosed before death. We report a case of pulmonary mucormycosis in a woman with poorly controlled diabetes mellitus. This is the first case in taiwan of pulmonary mucormycosis diagnosed preoperatively and treated successfully by lobectomy only. Persistent pulmonary lesions resistant to antibiotic treatment in high risk patients should arouse the suspicion of mucormycosis. Prompt bronchoscopic examination, open lung biopsy and transthoracic pulmonary aspiration cytology and biopsy should be done. Surgical resection of localized lesions remains the treatment of choice.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
5/8. orbital cellulitis due to mucormycosis. A case report.A case of orbital cellulitis caused by mucormycosis developed in a patient subsequent to cataract extraction and during systemic steroid treatment for postoperative complications. Fatal mucormycosis is a rare disease usually beginning with a subcutaneous inflammatory lesion. As the subsequent development of orbital cellulitis is very rare, little has been published on this subject. In cases of subcutaneous mucormycosis, the diagnosis can easily be made by means of histologic examination of the lesion. However, early diagnosis is difficult in cases with orbital involvement, because the most common cause of orbital cellulitis is bacterial. Thus, orbital cellulitis caused by mucormycosis is often wrongly treated with antibacterial agents only, as histologic examination is neither easy nor part of any routine investigation. Therefore, a combined treatment using antibiotics and antifungal agents in immunusuppressed patients with this disease is advocated.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
6/8. Phycomycosis as postoperative complication of urologic surgery.A case of phycomycosis (Mucor) complicating urologic surgery is presented. It is a rare disease that is rapidly fatal, though caused by a usually benign saphophytic fungus. No previous urologic surgical cases have been found in the literature where Mucor has been a postoperative complication.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
7/8. mucormycosis: experience with 10 patients.Rhinocerebral mucormycosis is a fulminating, devastating fungal disease, usually associated with debilitating diseases such as diabetes mellitus, leukaemia and immunosuppressive conditions. Ten patients with this rare disease have been treated over the past 14 years at the Beilinson Medical Centre. Nine patients had an underlying debilitating disease and one patient had latent diabetes mellitus which was diagnosed only after presentation of mucormycosis. Only two of the 10 patients survived. Early aggressive surgical debridement, together with amphotericin b and correction of underlying metabolic acidosis were found to be important factors associated with survival.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
8/8. Gastric mucormycosis due to rhizopus oryzae in a renal transplant recipient.Gastric mucormycosis is a rare disease with a reported fatal outcome of 98%. Manifestations range from colonization of peptic ulcers to infiltrative disease with vascular invasion and dissemination. In our renal transplant patient a deep gastric ulceration infected with rhizopus oryzae (class Zygomycetes), which is known to be an agent of mucormycosis, was diagnosed in the early posttransplant period after antirejection therapy. The infection was successfully managed with amphotericin b and omeprazole.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |