1/44. mumps virus neutralizing antibodies do not protect against reinfection with a heterologous mumps virus genotype.In April 1999, a previously healthy 22-year-old woman was taken ill with fever and bilateral swelling of the parotid glands. A chronic course of disease extending from April to December was found with swelling of the parotid glands, fatigue, low grade fever, episodes of tachycardia and nightswetting. mumps virus rna of genotype A character based on the SH (small hydrophobic) protein gene classification was demonstrated in three serum samples collected during the course of clinical disease. Different criteria for reinfection were fulfilled including demonstration of IgG antibodies by ELISA in a preinfection serum sample. The preinfection serum sample of the patient was able to efficiently neutralize the infectivity of a heterologous genotype D strain but was unable to neutralize the homologous genotype A virus. The findings in the present study may offer an explanation of a mechanism behind previously observed vaccine failures and the occurrence of reinfection with heterologous mumps virus strains.- - - - - - - - - - ranking = 1keywords = virus (Clic here for more details about this article) |
2/44. Mumps-like syndrome owing to parvovirus B19: a brief report.Major manifestations of acute parvovirus B19 infection are usually erythema infectiosum, transient aplastic crisis and polyarthropathy. We report a case suspected to have mumps-meningo-encephalitis who had IgM and IgG antibodies positive for parvovirus B19.- - - - - - - - - - ranking = 0.54545454545455keywords = virus (Clic here for more details about this article) |
3/44. Case report of meningoencephalitis during a concomitant mumps and parvovirus B19 infection.A 19-year-old, immunologically healthy man suffered from prolonged and intermittent high fever, left parotitis, systemic lymph node swelling, progressive liver dysfunction and leukocytopenia. 11 days after the fever onset, consciousness disturbance and generalized convulsion occurred. By the administration of gamma-globulin and steroid, the patient recovered completely. serum titers of IgG and IgM specific for both human parvovirus B19 and mumps were elevated, and parvovirus B19 dna was identified in the serum. It was speculated that overlap infection of mumps and parvovirus B19 made the disease more severe in this patient.- - - - - - - - - - ranking = 0.63636363636364keywords = virus (Clic here for more details about this article) |
4/44. mumps virus reinfection--clinical findings and serological vagaries.Sera taken from two cases of mumps reinfection were tested against different strains of mumps virus in a plaque reduction neutralisation assay. antibodies to mumps in the sera reacted with all strains, but the pattern of emergence of these antibodies differed with the strains tested. These findings raise the possibility of emergence of a mutant strain under the selective pressure of immunisation, with limited or no cross protection induced by the vaccine strain.- - - - - - - - - - ranking = 0.45454545454545keywords = virus (Clic here for more details about this article) |
5/44. priapism: an unusual complication of parotitis without orchitis.A 10-year-old white boy is described in whom priapism developed as a complication of parotitis without orchitis. Medical study failed to reveal any other etiology. The syndrome was assumed to be related to a mumps virus. Treatment by corpora cavernosa-spongiosum shunt relieved the acute symptoms as well as preserved the patient's ability to have an erection.- - - - - - - - - - ranking = 0.090909090909091keywords = virus (Clic here for more details about this article) |
6/44. Aqueductal stenosis 9 years after mumps meningoencephalitis: treatment by endoscopic third ventriculostomy.INTRODUCTION: hydrocephalus due to aqueductal stenosis following mumps meningoencephalitis is a rare condition, reported only in 16 cases in the literature. The pathogenetic role of the mumps virus in inducing aqueductal stenosis has been demonstrated experimentally in animal models and clinically proven in a few cases. Although obstructive in nature, the post-infectious etiology raises the question as to whether third ventriculostomy is the appropriate treatment. PATIENT: We report a case of hydrocephalus due to pure aqueductal stenosis occurring in an 11-year-old boy who suffered from mumps meningoencephalitis 9 years previously. The boy was successfully treated by endoscopic third ventriculostomy. CONCLUSIONS: The present case offers further evidence of the purely obstructive nature of the hydrocephalus induced by paramyxovirus meningoencephalitis, even if it did occur several years after the infectious disease. The pathogenesis of mumps-induced hydrocephalus and the rationale of treatment are discussed, and the literature is reviewed.- - - - - - - - - - ranking = 0.18181818181818keywords = virus (Clic here for more details about this article) |
7/44. hydrocephalus due to acute aqueductal stenosis following mumps infection: report of a case and review of the literature.An acquired form of hydrocephalus due to aqueductal stenosis developing as a sequela of mumps virus infection of the central nervous system is presented. Percutaneous third ventriculostomy and interventriculostomy (aqueduct cannulation) were performed using a flexible fiberoptic ventriculoscope. The aqueduct was blocked with amorphous material but was cleared with the scope. This is the first case of a fulminant phase of mumps ventriculitis leading to aqueductal stenosis, which has been treated using a ventriculoscope for the first time.- - - - - - - - - - ranking = 0.090909090909091keywords = virus (Clic here for more details about this article) |
8/44. Transcanal labyrinthectomy in childhood: report of a case.vertigo in children is caused by several factors. One such factor is viruses (e.g., mumps, measles, and rubeola) afflicting the inner ear by various mechanisms. In the majority of cases, affected patients improve with clinical therapy and vestibular rehabilitation. We present the case of a child with vertigo as a sequela of mumps virus infection that did not improve with clinical treatment and vestibular rehabilitation. Consequently, the child was submitted to a transcanal labyrinthectomy followed by vestibular rehabilitation, with significant postprocedure improvement of symptoms. We discuss surgical indications, the technique used in this case, and the importance of vestibular rehabilitation in the postoperative period.- - - - - - - - - - ranking = 0.18181818181818keywords = virus (Clic here for more details about this article) |
9/44. Mumps epididymo-orchitis with prolonged detection of virus in semen and the development of anti-sperm antibodies.Epididymo-orchitis is the most common complication of mumps in post-pubertal men. A case of MMR vaccine failure, in whom mumps and mumps-associated unilateral epididymo-orchitis developed, is presented in this article. mumps virus was isolated from the semen 14 days after onset and mumps rna was detected in semen for up to 40 days using RT-PCR. Epididymo-orchitis was associated with transient but significant reduction in sperm count and severe abnormalities in sperm morphology. It also led to the appearance of anti-sperm antibodies, which may have potential long-term adverse effects on the patient's fertility. Sequencing of the SH gene of the virus showed this to be a new mumps genotype distinct from the virus circulating currently in the UK.- - - - - - - - - - ranking = 0.63636363636364keywords = virus (Clic here for more details about this article) |
10/44. Mumps-induced corneal endotheliitis.OBJECTIVE: To report two cases of corneal endotheliitis following mumps parotitis. methods: Observational case reports of two patients presenting with sudden unilateral diminution of vision while they were in the resolution phase of mumps parotitis. RESULTS: Central corneal edema with no associated epithelial involvement or iridocyclitis was confirmed on slit-lamp biomicroscopy. Specular microscopy confirmed an increased corneal thickness with corneal endothelial abnormalities. The diagnosis of mumps virus infection was established through detection of IgM antibody in serum samples of the patients using enzyme-linked immunosorbent assay (ELISA). The routine investigations for other systemic diseases were negative. CONCLUSIONS: Corneal endotheliitis as a sequela to mumps is a new reported association. Timely treatment with topical steroids led to resolution of the disease with full visual recovery without any residual symptoms or signs.- - - - - - - - - - ranking = 0.090909090909091keywords = virus (Clic here for more details about this article) |
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