1/155. Intramuscular mixed tumour with clonal chromosomal changes.A case of an entirely intramuscular mixed tumour occurred in an 82-year-old man, who presented with a large mass in the region of the right triceps muscle. A lobulated tumour was seen, with plump, round epithelioid cells embedded in a chondromyxoid stroma. Immunohistochemical examination showed strong S100 protein and pancytokeratin positivity in most of the tumour cells. cytogenetic analysis revealed complex clonal chromosomal changes: 47, XY, i(2) (q10), -15, der(17) t(15; 17) (q11; p12), r. Differential diagnosis against extraskeletal myxoid chondrosarcoma (EMC) may be problematic, particularly in an incisional biopsy. Chromosomal analysis can be very helpful in solving this problem, since EMC shows a specific reciprocal chromosome translocation characterised as t (9;22) (q22-31) (q11-12).- - - - - - - - - - ranking = 1keywords = sarcoma (Clic here for more details about this article) |
2/155. ring chromosomes in a malignant mesenchymoma.We report, for the first time, the cytogenetic and molecular genetic constitution of a human mesenchymoma. As in several other soft tissue sarcomas, supernumerary ring and rod-shaped marker chromosomes were observed next to an otherwise normal diploid karyotype. Comparative genomic in situ hybridization and whole chromosome painting experiments revealed that chromosome 1q21-q25 and 12q14-q15 sequences were amplified, and that these sequences resided on the supernumerary marker chromosomes. We assume that, in this malignant mesenchymoma, the observed chromosomal anomalies may be associated with its well differentiated liposarcomatous component.- - - - - - - - - - ranking = 2.00713229481keywords = sarcoma, soft (Clic here for more details about this article) |
3/155. leiomyosarcoma of the diaphragm.An asymptomatic, intrathoracic mass was found on imaging studies in a 53-year-old man. After excision it proved to be an extrapulmonary leiomyosarcoma, a rare malignancy of smooth muscle, originating from the right diaphragm. The location of this malignant tumor is rare in an adult. The tumor was resected, the diaphragm was reconstructed, and the patient should have a long-term cure and good quality of life.- - - - - - - - - - ranking = 5keywords = sarcoma (Clic here for more details about this article) |
4/155. chondrosarcoma in a patient with McCune-Albright syndrome. Report of a case.A case of McCune-Albright syndrome with acromegaly and chrondrosarcoma is reported. The potential role of chronic growth hormone overproduction in the occurrence of malignant transformation and the possible value of bisphosphonates in the treatment of bone fibrous dysplasias are discussed.- - - - - - - - - - ranking = 5keywords = sarcoma (Clic here for more details about this article) |
5/155. Intramuscular solitary fibrous tumor: a clinicopathological case study.We present a case of extrapleural solitary fibrous tumor arising within the muscle, an unusual and hitherto-undescribed tumor lesion. A 42-year-old woman presented a painless mass in her left thigh. The lesion was depicted as an intramuscular mass that enhanced on both CT and MRI, showing quite rich tumor vascularity. The histological features of the tumor were spindle cell proliferation with various histological patterns, typical fibrocollagenous background, and positive immunoreactivity for CD-34.- - - - - - - - - - ranking = 0.054000681111183keywords = spindle cell, spindle (Clic here for more details about this article) |
6/155. US and CT findings of multicentric leiomyosarcomatosis.This article presents a case of leiomyosarcomatosis with widespread lesions involving the soft tissues and the most unlikely organs such as thyroid and salivary glands, pancreas, ligamentum teres, bladder wall, and bones without lymph node or distant metastasis. The CT and US findings of this rare phenomenon are discussed with regard to the literature.- - - - - - - - - - ranking = 5.00713229481keywords = sarcoma, soft (Clic here for more details about this article) |
7/155. Osteogenic sarcoma with skeletal muscle metastases.Two cases of osteogenic sarcoma with skeletal muscle metastases are described. A 40-year-old woman presented with progressive swelling of both calves and a soft tissue back lump. She had been diagnosed with mandibular chondroblastic osteogenic sarcoma 6 years earlier. Radiographs showed calcified masses. MRI scans and bone scintigraphy revealed multiple soft tissue masses in both calves. Bone scintigraphy also showed uptake in the back lump, right thigh and left lung base. biopsy confirmed metastatic chondroblastic osteogenic sarcoma, which initially responded well to chemotherapy. However, the metastatic disease subsequently progressed rapidly and she died 21 months after presentation. The second case concerns a 20-year-old man who presented with a pathologic fracture of the humerus, which was found to be due to osteoblastic osteogenic sarcoma. He developed cerebral metastases 17 months later, followed by metastases at other sites. Calcified masses were subsequently seen on radiographs of the abdomen and chest. CT scans confirmed the presence of densely calcified muscle metastases in the abdominal wall, erector spinae and gluteal muscles. The patient's disease progressed rapidly and he died 30 months after presentation.- - - - - - - - - - ranking = 8.01426458962keywords = sarcoma, soft (Clic here for more details about this article) |
8/155. pancreaticoduodenectomy for metastatic tumors to the periampullary region.Although operative resection of metastatic lesions to the liver, lung, and brain has proved to be useful, only recently have there been a few reports of pancreaticoduodenectomies in selected cases of metastases to the periampullary region. In this report we present four cases of proven metastatic disease to the periampullary region in which the lesions were treated by pancreaticoduodenectomy. Metastatic tumors corresponded to a melanoma of unknown primary site, choriocarcinoma, high-grade liposarcoma of the leg, and a small cell cancer of the lung. All four patients survived the operation and had no major complications. Two patients died of recurrence of their tumors, 6 and 63 months, respectively, after operation; the other two patients are alive 21 and 12 months, respectively, after operation. It can be inferred from this small but documented experience, as well as a review of the literature, that pancreaticoduodenectomy for metastatic disease can be considered in selected patients, as long as this operation is performed by experienced surgeons who have achieved minimal or no morbidity and mortality with it.- - - - - - - - - - ranking = 1keywords = sarcoma (Clic here for more details about this article) |
9/155. Intramuscular spindle cell hemangioendothelioma.Spindle cell hemangioendothelioma occurring in skeletal muscle is extremely rare. No reported studies have performed an imaging evaluation of intramuscular spindle cell hemangioendothelioma. We report on such a tumor arising in an unusual site, the right extensor digiti minimi, in a 46-year-old woman. An en bloc resection was performed and the patient has been disease free for 8 years. Radiologic imaging in the present case showed similar findings to those described in intramuscular hemangioma.- - - - - - - - - - ranking = 0.27000340555592keywords = spindle cell, spindle (Clic here for more details about this article) |
10/155. Ossifying intramuscular metastasis from colon cancer: report of a case.PURPOSE: This report presents a patient who developed severe buttock pain because of an ossified intramuscular metastasis from a sigmoid colon cancer. methods: This is a case report and review of the literature for intramuscular metastasis from colon cancer. RESULTS: Computed tomography and magnetic resonance imaging showed a soft-tissue mass with heavy calcification. Histologically, mature compact bone was observed with adenocarcinoma cells dispersed among the bony trabeculae. CONCLUSION: When an intramuscular mass is seen, even if it contains extensive calcification, metastasis from colon cancer should be included in differential diagnosis.- - - - - - - - - - ranking = 0.0071322948099817keywords = soft (Clic here for more details about this article) |
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