Cases reported "Muscular Diseases"

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1/10. pyomyositis in the acquired immunodeficiency syndrome.

    pyomyositis, a purulent infection of skeletal muscle, is usually caused by staphylococcus aureus. Many cases of pyomyositis in human immunodeficiency virus (hiv) seronegative patients have been reported in north america and have been reviewed extensively. Moreover, pyomyositis has been reported in association with hiv infection in patients with or without the acquired immunodeficiency syndrome (AIDS). We describe two patients with pyomyositis and hiv and review the available English language literature. leukocytosis and bacteremia tend to occur less frequently in those with hiv infection and pyomyositis. However, fever, S aureus infection, and bilateral involvement occur more frequently in hiv-positive patients. Antibiotic therapy together with surgical drainage or aspiration is usually sufficient.
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keywords = pyomyositis
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2/10. pyomyositis. A literature review.

    pyomyositis is a primary bacterial infection of the skeletal muscles. It is known as tropical myositis as most cases have been reported in patients living in tropical areas and, until recently, it was considered unusual in the temperate zone. The condition is usually diagnosed late, and for this reason it is followed by an increased morbidity and sometimes a significant mortality rate. A review of the literature indicates a possibly rising incidence in non-tropical areas. This condition should be considered in patients with muscle pain, fever, leucocytosis, elevated ESR and CRP, in tropical and non-tropical countries, in previously healthy patients as well as in patients suffering other health problems, particularly hiv infection. An MRI investigation should be performed early as it is the imaging technique of choice during the first stage of the disease. A case of a primary iliopsoas pyomyositis diagnosed during the initial stage using MRI is presented as an illustration.
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keywords = pyomyositis
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3/10. pyomyositis during induction chemotherapy for acute lymphoblastic leukemia.

    Herein, we report on the correct diagnosis and effective treatment procedures for pyomyositis, a very rare complication that remains a diagnostic challenge in children being treated for acute lymphoblastic leukemia (ALL). We report the case of a 10-year-old girl suffering from pyomyositis with ALL. Correct diagnosis is usually delayed because the initial symptom of pyomyositis, usually local pain, is similar to the common side effect of vincristine, a drug necessary for ALL induction therapy. We summarize the procedures taken to reach a timely diagnosis and therapeutic success.
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ranking = 0.75
keywords = pyomyositis
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4/10. Staphylococcal pyomyositis in patients infected by the human immunodeficiency virus.

    PURPOSE: We describe the manifestations of spontaneous staphylococcal pyomyositis in patients infected by the human immunodeficiency virus (hiv). patients AND methods: We present the courses of five previously unreported patients infected by hiv who presented to our medical centers with spontaneous staphylococcal pyomyositis. Additionally, we review all previously reported cases of this entity in hiv-infected patients and discuss its possible pathogenesis and importance in the context of hiv infection. RESULTS: All patients presented with gradually developing fever and localized pain and swelling without accompanying leukocytosis. Often only scant evidence of local inflammation was found. None of our patients used intravenous drugs, had a history of trauma, had hiv- or zidovudine-related myositis, or had other conditions known to be associated with serious staphylococcal infections. Two patients studied had normal serum levels of all IgG subclasses. Elevated serum IgE, eosinophilic inflammatory infiltrates, or marked peripheral eosinophilia was observed in two patients. CONCLUSIONS: Staphylococcal pyomyositis in hiv-infected patients presents in an indolent fashion, which may delay appropriate diagnosis and treatment. Since staphylococcal pyomyositis is infrequently reported in the united states, the development of 14 such cases (five in this series and nine previously reported) among the first 140,000 cases of acquired immunodeficiency syndrome in this country implies that this patient population is predisposed to this infectious complication. The pathogenesis of this entity is uncertain, but it is notable that hiv-infected patients are commonly colonized by staphylococcus aureus and that neutrophils from hiv-infected patients frequently manifest phagocytic, chemotactic, and oxidative defects, diminished expression of Fc tau RIII (CD16) and CR1, and impaired bactericidal activity against S. aureus.
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keywords = pyomyositis
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5/10. pyomyositis in patients with the human immunodeficiency virus: an unusual form of disseminated bacterial infection.

    PURPOSE AND patients: pyomyositis, a common disease in the tropics, is rare in the continental united states, with approximately 83 cases described in the literature in the past two decades. The occurrence of pyomyositis complicating human immunodeficiency virus (hiv) infection has been reported in 10 patients since 1986. We report six cases of this entity in patients with advanced hiv disease seen in our institution over a 20-month period. A common denominator in all of our patients was muscle injury, induced by either exercise or trauma. Unlike most previous reports of hiv-associated pyomyositis, the clinical picture in our cases was complicated by the development of abscesses in multiple muscle groups, requiring prolonged antimicrobial therapy and repeated drainage procedures for successful management. Interestingly, one patient developed concomitant rhabdomyolysis--an otherwise rare event in classical pyomyositis. staphylococcus aureus was the predominant infecting organism in this as well as all other series. Of note, we also observed and report the first case, to our knowledge, of gram-negative pyomyositis in an hiv-infected individual. The pathogenic implications of this catalase-producing gram-negative isolate are discussed in the context of neutrophil abnormalities in hiv disease. CONCLUSION: Like tropical pyomyositis, its hiv-associated counterpart appears to be multifactorial in origin. Its recent recognition suggests that, in addition to underlying abnormalities of host defense, factors relating to the prolonged survival of patients with late-stage disease, including myopathy, might play an important contributory role.
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ranking = 1.25
keywords = pyomyositis
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6/10. osteomyelitis in tropical pyomyositis: a case report.

    We report a case of acute tropical pyomyositis in a German girl living in tanzania. The course of the disease was complicated by osteomyelitis affecting the humerus, which is unusual in tropical pyomyositis. diagnosis of the osteomyelitis was difficult because a scintigram showed depressed bone activity during the isotope influx and bloodpool phase. The bone phase was abnormal with irregular hypo- and hyperfixation of tracer.
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ranking = 1.5
keywords = pyomyositis
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7/10. pyomyositis in spinal cord injury patients.

    bacterial infections remain a major cause of morbidity and mortality among patients with longstanding spinal cord injury. Infection may occur in a number of different foci, often taxing the skill of the most accomplished diagnostician. Herein are described three patients with fever of unknown origin wherein extensive diagnostic workups ultimately led to the diagnosis of primary pyomyositis. These patients demonstrate the importance of repeated careful physician examination in determining the site of infection in patients with established sensorimotor deficits. Although primary pyomyositis is not a common occurrence in those with spinal cord injuries, it should be included as a potential cause of fever in this patient population.
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keywords = pyomyositis
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8/10. pyomyositis: a differential diagnosis from sarcoma.

    A case of pyomyositis, a deep muscle abscess, presenting as a soft tissue sarcoma is reported. Although common in the tropics, this disease is quite rare in the united states. The presentation, diagnosis, and treatment of the problem are discussed and reviewed.
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keywords = pyomyositis
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9/10. pyomyositis during induction chemotherapy for acute lymphocytic leukemia.

    PURPOSE: pyomyositis is a rare disease in temperate climate regions and frequently has a subacute presentation. Because of this, the entity is often misdiagnosed. patients AND methods: Two boys with acute lymphocytic leukemia (ALL) who presented with muscle pain, shortly after receiving induction chemotherapy, were evaluated. RESULTS: Presenting physical examination and laboratory findings were unremarkable except for extremity pain and tenderness. These symptoms were initially attributed to a neurotoxic side effect of vincristine. As the children's symptoms progressed, muscle abscess formation was finally delineated by gallium and computed tomography scans, and the diagnosis of pyomyositis was made. In both cases, the invading organism was staphylococcus aureus. Both children responded well to incision and drainage of the abscesses and antibiotic therapy. CONCLUSION: Four cases of pyomyositis occurring in ALL patients shortly after induction chemotherapy have now been described. We feel that when children from this population present with muscle pain, pyomyositis should be part of the differential diagnosis. With early medical and surgical intervention, morbidity and mortality can be avoided.
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ranking = 0.75
keywords = pyomyositis
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10/10. Tuberculous skeletal muscle involvement in acute leukemia: report on two cases.

    Bacterial infection of skeletal muscle (pyomyositis) is usually followed by abscess formation. The most commonly isolated pathogen is staphylococcus aureus. tuberculosis rarely affects patients with acute leukemia. The authors report on 2 patients, one with acute myelogenous leukemia and the other with acute lymphoblastic leukemia whose clinical course was complicated by tuberculous skeletal muscle abscesses. In both instances, musculoskeletal pain was accompanied by evidence of muscle abscesses by imaging studies of the painful areas. Therefore, in patients with acute leukemia and evidence of muscle abscesses with initial cultures negative for bacteria and fungi, one should include tuberculosis in the differential diagnosis.
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ranking = 0.25
keywords = pyomyositis
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