1/30. Human herpesvirus-7 infection of the CNS with acute myelitis in an adult bone marrow recipient.The beta-herpesviruses, human herpesviruses-6 and -7 (HHV-6 and HHV-7), are closely related and have very similar biological behaviour. While HHV-6 is associated with encephalitis in immunosuppressed adults, HHV-7 is not recognised as a cause of neurological disease in such patients. This report describes the identification of a reactivated HHV-7 infection in the cerebrospinal fluid of an adult who presented with an acute myelitis 11 months after unrelated donor bone marrow transplant.- - - - - - - - - - ranking = 1keywords = herpes (Clic here for more details about this article) |
2/30. herpes zoster myelitis: report of two cases.Two male patients aged 40 and 45 years with hiv infection and paraplegia are presented. The two had sub-acute onset paraplegia with a sensory level, which developed 10 days after herpes zoster dermatomal rash. They both had asymmetrically involvement of the lower limbs. Investigation including imaging of the spinal cord did not reveal any other cause of the neurological deficit. The two responded very well to treatment with acyclovir. herpes zoster myelitis is a condition likely to rise with the upsurge of hiv infection and there is a need to identify the condition early. We also review the literature on the subject.- - - - - - - - - - ranking = 0.16666666666667keywords = herpes (Clic here for more details about this article) |
3/30. Recurrent herpes zoster myelitis treated with human interferon alpha: a case report.Recurrent herpes zoster myelitis is very rare. However, a case was recently observed in our hospital. A 43-year-old woman developed myelitis 2 weeks after development of shingles. Her condition was improved by methylprednisolone. Seven months later, she developed myelitis after development of shingles again. Antibody against varicella-zoster (VZV), increased in the serum, but was negative in the cerebrospinal fluid. methylprednisolone was not sufficiently effective against this attack. The refractory sensory disturbance was improved by human interferon alpha (IFN-alpha). Natural killer cell activity, the helper T-cell/suppressor T-cell ratio and the kappa/lambda ratio of B-cells increased with clinical improvement. In this case, delayed-type hypersensitivity after VZV infection played a role in the occurrence of myelopathy and clinical improvement resulted from the immunosuppressive effects of IFN-alpha.- - - - - - - - - - ranking = 0.83333333333333keywords = herpes (Clic here for more details about this article) |
4/30. herpes zoster myelitis: MR appearance.The author describes a 71-year-old woman in whom cutaneous cervical herpes zoster was complicated by the development of cervical myelitis. T2-weighted MR showed two focal areas of hyperintensity in the cervical cord and suggested a slight enlargement at C2-C3 and C7.- - - - - - - - - - ranking = 0.16666666666667keywords = herpes (Clic here for more details about this article) |
5/30. Cervical myelitis from herpes simplex virus type 1.Although subacute ascending paralysis without sensory involvement is typically evocative of guillain-barre syndrome, it can alternatively be due to infection or inflammation of the spinal cord. We describe a 16-month-old female who presented with ascending flaccid paresis after an upper respiratory tract infection. She then developed signs of upper motor neuron involvement of the lower limbs associated with upper motor neuron involvement of the upper limbs. Motor nerve conduction and electromyographic studies of upper limbs demonstrated anterior horn cell involvement. neuroimaging was consistent with cervical myelitis, and cerebrospinal fluid polymerase chain reaction was positive for herpesvirus-1. Although association with the primary infection of the respiratory tract may be fortuitous, possible neurotropic or hematogenous spread of herpesvirus-1 to the cervical spinal cord cannot be excluded. She then developed signs of upper motor neuron involvement of the lower limbs associatred with lower motor neuron involvement of the upper limbs [corrected].- - - - - - - - - - ranking = 2.7249909383582keywords = herpes simplex, herpes, simplex (Clic here for more details about this article) |
6/30. Painful legs and moving toes syndrome associated with herpes zoster myelitis.A 75-year-old woman developed painful legs and moving toes syndrome (PLMT) 16 months after the onset of herpes zoster (HZ) myelitis. Although the scattered extensive lesions due to HZ myelitis were observed to be eccentric near the posterior horn on MRI, these changes had disappeared upon the development of PLMT. Combined median and tibial nerve somatosensory evoked potentials demonstrated abnormal findings only in the tibial nerve stimuli, suggesting that a severe alteration occurred in the somatosensory fibers coming selectively from the lower legs. These findings suggest plasticity in the ascending somatosensory pathway including the posterior horn cells, probably involving the interneuron networks, for the lower legs may underlie the development of PLMT associated with HZ myelitis.- - - - - - - - - - ranking = 0.83333333333333keywords = herpes (Clic here for more details about this article) |
7/30. Sacral myeloradiculitis complicating genital herpes in a hiv-infected patient.Myeloradiculitis is a rare neurological complication of herpes simplex type 2 (HSV-2) infection, frequently associated with a fatal outcome. Among patients with hiv infection, HSV-2 myeloradiculitis has occasionally been reported, always associated with advanced immunosuppression and AIDS. We report a patient with hiv infection but no history of previous opportunistic infections, who developed sacral myeloradiculitis immediately after an episode of genital herpes. Magnetic resonance imaging with gadolinium showed necrotizing myelitis in the conus medullaris and enhancement of sacral roots. cd4 lymphocyte count was 530/mm3. Other possible causes of myeloradiculitis in hiv-infected patients were appropriately excluded. acyclovir therapy resulted in partial clinical improvement. This report shows that myeloradiculitis as a complication of genital herpes may occur in the early stages of hiv infection and may have a favourable outcome with antiviral treatment.- - - - - - - - - - ranking = 1.5979144012562keywords = herpes simplex, herpes, simplex (Clic here for more details about this article) |
8/30. A case of herpes zoster myelitis: positive magnetic resonance imaging finding.A 33-year-old man developed a progressive myelopathy after a characteristic skin lesion of herpes zoster involving the right C3 and C4 dermatomes. The lesions were recognizable in the T2-weighted image of the magnetic resonance imaging (MRI) as increased signal intensities throughout the long segments of the spinal cord with maximal in the cervical portion, which was compatible with the pathological findings reported in autopsy studies.- - - - - - - - - - ranking = 0.83333333333333keywords = herpes (Clic here for more details about this article) |
9/30. Necrotizing myelopathy associated with malignancy caused by herpes simplex virus type 2: clinical report of two cases and literature review.Two cases of necrotizing myelopathy, one with lung carcinoma and the other with adult T cell leukemia (ATL), displayed flaccid paraplegia and sphincter dysfunction. Both cases did not show any direct neoplastic cell invasion of the spinal cord. Pathologically, diffuse and random necrosis was found in the spinal cord in both cases. In the case of ATL, small numbers of inclusion bodies in the nerve cell nuclei were demonstrated. Using polyclonal and also monoclonal antibodies, herpes simplex virus type 2 (HSV-2) was clearly demonstrated in the spinal cord in both cases. By electron microscopy, numerous herpes virus particles were observed in the spinal cord in both cases. The usefulness of electrophysiological studies should be emphasized in the differentiation of these cases from others which might also display flaccid paraplegia. The possibility of necrotizing myelopathy caused by HSV-2 should always be considered in the differential diagnosis of spinal cord diseases displaying flaccid paraplegia.- - - - - - - - - - ranking = 3.1562386729478keywords = herpes simplex, herpes, simplex (Clic here for more details about this article) |
10/30. Unusual manifestations of herpes zoster. A clinical and electrophysiological study.The literature on complicated herpes zoster is summarized in this paper. The case histories of 18 patients with herpes zoster are presented. Two patients had encephalitis, 2 had myelitis and the other 14 patients had various types of lower motor neurone disturbance. Both patients with encephalitis--one of who developed choreo-athetosis during the illness--recovered fully. Only 1 of the 2 patients with myelitis recovered fully; the other remains severely paraparetic and the reason for her incomplete recovery may be related to the presence of generalized arteriolar disease associated with seronegative rheumatoid disease. One patient developed a guillain-barre syndrome 3 weeks after the onset of herpes zoster. Recovery in the 15 patients with lower motor neurone involvement has been slow butcomplete--or almost complete--in all but 1, a patient with persistent facial weakness as part of the Ramsay Hunt syndrome and who also had weakness of one upper limb. Seven other patients had lower limb weakness. In 2 patients the weakness was confined to abdominal myotomes and 2 other patients had urinary retention. Electromyographic abnormalities were found in the muscles which were weak and frequently also in muscles which appeared strong. It is emphasized that neurological disturbances other than sensory abnormalities may be found in patients with herpes zoster. Motor complications of various types are not uncommon.- - - - - - - - - - ranking = 1.3333333333333keywords = herpes (Clic here for more details about this article) |
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