Cases reported "Myxoma"

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1/20. Treatment of life-threatening huge atrial myxoma: report of two cases.

    We herein report two patients with left atrial myxoma who needed an emergency operation. Case 1 was a 48-year-old woman who was injured in a traffic accident and underwent an operation for a right leg fracture. Just after the operation she developed cardiac and respiratory arrest with complaints of chest pain. She was successfully resuscitated and diagnosed to have a left atrial myxoma by echocardiography. Emergency surgery was performed and a giant left atrial myxoma was thus removed from the atrial septum. Case 2 was a 54-year-old housewife who was transferred to our department under the diagnosis of a left atrial myxoma by echocardiography. She complained of dyspnea and chest discomfort. By angiography, the tumor was seen to be partially incarcerated at the diastolic phase. A huge myxoma was removed from the atrial septum which was secured by a patch closure. Cardiac echocardiography can help rule out left atrial myxoma if it is highly suspected. As early surgical mortality is low and the long-term results are good, we strongly believe that patients with cardiac myxoma should be operated on as early as possible, once a diagnosis is made.
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2/20. A survivor of near sudden death caused by giant left atrial myxoma.

    Sudden hemodynamic collapse occurred in a 20-year-old man after an Emergency Department visit with a complaint of dizziness and chest discomfort. A left atrial myxoma was demonstrated by echocardiography. resuscitation procedures followed by surgical repair resulted in an excellent outcome. Although sudden death is a serious manifestation of cardiac myxoma, reports of survivors of near sudden death caused by this tumor have been rare.
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3/20. Giant cardiac myxoma with malignant transformed glandular structures.

    A case of a right-sided giant cardiac myxoma with malignant transformation of glandular structures causing systemic metastases is described. Plain chest radiography and computed tomography localized the tumor within the heart. Exact depiction of the origin of the tumor using subtracted 2D-projection MR angiography is documented. Radiologic findings and differential diagnosis of this unique tumor are discussed.
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4/20. myxoma mix-up. A case report.

    We present a 63-year-old lady who had atrial myxoma. The diagnostic difficulties distinguishing this from giant cell arteritis are highlighted. In particular, both conditions caused choroidal and retinal infarcts, anterior ischaemic optic neuropathy, with raised acute phase reactants. The authors stress the importance of continued ophthalmoscopy as the fundal changes become more apparent.
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5/20. Giant-cell-rich myxoma of right atrium. An ultrastructural analysis.

    myxoma is the commonest primary tumor of the heart, arising more frequently in the left than the right atrium. Here, we report a case of right atrial myxoma, arising close to the entry of the inferior vena cava, which is rich in multinucleated giant cells. No glandular elements were identified. Ultrastructural analysis of the giant cells was carried out, which revealed these giant cells to be of similar morphology as the mononuclear cells, suggesting their formation by fusion of individual tumor cells. Immunostain for vimentin and desmin showed positivity in the giant cells as well as cells with single nucleus, further confirming these observations.
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6/20. Unusually large left atrial myxoma presenting with severe mitral valve obstruction symptoms.

    A 13-year-old girl with the complaint of severe mitral valve obstruction symptoms was diagnosed as having an unusually large left atrial tumor by echocardiography. The giant mass was surgically removed and the postoperative course was uneventful. Histologic examination confirmed the mass was a benign atrial myxoma.
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7/20. Coronary artery aneurysms mimicking cardiac tumor.

    AIMS: To discuss the diagnosis of giant coronary aneurysms. methods AND RESULTS: We describe three patients in whom initial echocardiographic findings suggested cardiac tumors in the right atrium. Additional examination proved the tumor-like structures to be giant atherosclerotic coronary aneurysms of either the right coronary artery or its saphenous vein coronary bypass graft. CONCLUSION: Giant coronary aneurysms are an important differential diagnosis for cardiac tumors.
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8/20. Giant left atrial myxoma in a patient with mitral insufficiency: case report.

    We describe a 57-year-old female patient with left atrial giant myxoma and peroperative defined mitral insufficiency who underwent surgery with a diagnosis of a left atrial myxoma without accompanying mitral insufficiency. Although no clinical findings of mitral insufficiency were noticed preoperatively, after myxoma resection moderate mitral insufficiency was observed during surgery. Mitral insufficiency was repaired with annuloplasty. The patient recovered without complication.
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9/20. Multiple cerebral aneurysms as delayed complication of left cardiac myxoma: a case report and review.

    Left cardiac myxoma and also consecutive embolization into the brain is well documented, whereas the association of myxomas with multiple fusiform cerebral aneurysms is rare. We analyze 33 previously reported patients and present a case of a 43-year-old woman with multiple cerebral infarctions 2 years after resection of a recurrent myxoma in the left atrium. cerebral angiography displayed multiple fusiform aneurysms of several cerebral arteries, including a giant aneurysm of the basilar artery. serum level of interleukin-6 (IL-6) was highly elevated. The clinical, radiological and pathological features of these aneurysms are summarized. The pathogenesis, including the role of IL-6 in the formation of myxomatous aneurysms, is discussed.
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10/20. Giant paraovarian myxoma.

    We present an extremely rare case of a successfully operated giant (6700 g) paraovarian myxoma and uterus myomatosus in a 49-year-old woman. Preoperative examination (biochemical investigations, ultrasound and computed tomography scan) and perioperative findings did not identify a malignant tumor so that total abdominal hysterectomy/bilateral salpingo-oophorectomy and tumorectomy was chosen to treat the patient. Histologically, the tumor was clearly differentiated from the surrounding tissue. In solid regions there were spindle-shaped cells arranged in sheaves and within the profuse, well-vascularized myxomatous stroma there were star-shaped cells. Immunohistochemical analysis showed that tumor cells were positive to vimentin and smooth muscle actin. Electron microscopic analysis showed that tumor cells had ultrastructural characteristics that corresponded to cells in fibroma and thecoma in a profuse intercellular matrix, which confirmed the result of light microscopy.
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