1/31. Eruptive vellus hair cyst in a patient with pachyonychia congenita.pachyonychia congenita is characterized by symmetrical nail dystrophy, palmoplantar keratoderma, oral leukokeratosis, and follicular hyperkeratosis. In addition to these features, multiple cutaneous cysts of various kinds have been described. We report a case of pachyonychia congenita associated with eruptive vellus hair cyst.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
2/31. A case of erythema elevatum diutinum associated with B-cell lymphoma: a rare distribution involving palms, soles and nails.We report a case of erythema elevatum diutinum (EED) in association with malignant B-cell lymphoma. A 62-year-old man developed EED with an unusual distribution involving the palms, soles and nails. Treatment with dapsone was effective for his skin and nails until he developed generalized lymphadenopathy which turned out to be malignant lymphoma. Many haematological diseases, e.g. IgA paraproteinaemia and myeloma, have been reported in association with EED, but not malignant lymphoma. Even though it may just be a coincidence, we would like to add malignant lymphoma as one of the diseases associated with EED because the activity of EED and malignant lymphoma fluctuated in parallel.- - - - - - - - - - ranking = 5keywords = palm (Clic here for more details about this article) |
3/31. Eruptive vellus hair cyst and epidermoid cyst in a patient with pachyonychia congenita.We report the first case of pachyonychia congenita (PC) associated with both eruptive vellus hair cyst (EVHC) and epidermoid cyst. The patient is a 12-year-old Japanese girl who presented with two natal teeth at birth. She had thickening and discoloration of the fingernails and toenails, plantar hyperkeratosis, palmar-plantar hyperhidrosis and multiple cutaneous cysts. Histologic examination revealed EVHC and epidermoid cyst.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
4/31. skin and nail changes in children with sickle cell anemia receiving hydroxyurea therapy.skin and nail changes from long-term hydroxyurea therapy are reported in adults. skin and nail changes, including nail hyperpigmentation, longitudinal bands, and hyperpigmentation of the palms and other skin surfaces, developed in 7 children with sickle cell anemia after 6 to 16 weeks of hydroxyurea therapy. Cutaneous and nail changes may occur in children receiving hydroxyurea.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
5/31. The definition of trichophyton rubrum syndrome.Although chronic widespread dermatophyte infection is reported widely in the literature, neither a uniform nomenclature, nor even a clear definition of this syndrome have been established so far. Thus, we suggest trichophyton rubrum syndrome (TRS) for denomination and define the following obligatory clinical and mycological criteria for TRS. (A) skin lesions at the following four sites: (1) feet, often involving soles; (2) hands, often involving palms; (3) nails; and (4) at least one lesion in another location than (1) (2) or (3), except for groins. (B) Positive microscopic analyses of potassium hydroxide preparations of skin scrapings in all four locations. (C) Identification of trichophyton rubrum by cell culture at three of the four locations at least. For diagnosis of TRS the criteria (A) and (B) and (C) have to be fulfilled. This standardization is a prerequisite for further investigations of underlying mechanisms of this disease. The typical clinical pattern of TRS is illustrated by the presentation of two paradigmatic cases.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
6/31. A novel connexin 30 mutation in Clouston syndrome.Clouston syndrome (hidrotic ectodermal dysplasia) is an autosomal dominant ectodermal dysplasia characterized by alopecia, palmoplantar hyperkeratosis, and nail dystrophy. Recently, mutations in the GJB6 gene encoding the gap junction protein connexin 30 have been shown to cause this disorder. To date, all mutations have involved two codons: G11R and A88V. Here, we report a novel mutation V37E within the first transmembrane domain of connexin 30 in a spontaneous case of Clouston syndrome. The mutation was detected in genomic dna, confirmed in reverse transcription polymerase chain reaction products, and was excluded from 100 ethnically matched control individuals by restriction enzyme analysis.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
7/31. Dermatopathia pigmentosa reticularis: a report of a family demonstrating autosomal dominant inheritance.Dermatopathia pigmentosa reticularis is a rare heritable disorder consisting of a triad of cutaneous findings including reticulate hyperpigmentation, noncicatricial alopecia, and onychodystrophy. In addition to this triad, other variable features of dermatopathia pigmentosa reticularis have been described, including adermatoglyphia, hypohidrosis or hyperhidrosis, and palmoplantar hyperkeratosis. Only 10 cases have been described in the world literature to date, and no clear inheritance pattern has been demonstrated. We present a patient with the classic features of the dermatopathia pigmentosa reticularis triad, along with adermatoglyphia, hypohidrosis, and punctate hyperkeratosis of the palms and soles. A family pedigree demonstrates the autosomal dominant inheritance of dermatopathia pigmentosa reticularis.- - - - - - - - - - ranking = 2keywords = palm (Clic here for more details about this article) |
8/31. Acral hyperpigmented macules and longitudinal melanonychia in AIDS patients.Two patients with AIDS are described who developed acral hyperpigmented macules of the fingers, palms and soles, buccal mucosa and genitalia, associated with longitudinal melanonychia. These pigmentary changes seemed to be independent of zidovudine and were associated in one with diffuse melanoderma and elevated levels of alpha-msh. Histological and ultrastructural studies showed an increase of the dendrites and pigmentation of the melanocytes and few melanosomes in the keratinocytes.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
9/31. Vertically growing ectopic nail.A 64-year-old Japanese woman with an ectopic nail at the palmar tip of the left middle finger is reported. Interestingly, the nail grew vertically to a line horizontal to the surface epidermis. Atypically, it appeared at 60 years of age with no prior injury or trauma to explain inoculation of a nail matrix into the regional skin. Roentgenographically, there were no abnormal findings such as Y-shaped bifurcation of the distal phalanx of the affected finger. There are conflicting opinions concerning whether or not a proximal nail fold is critical for the nail to grow outward instead of upward. Although the present case had a wide proximal nail fold, it did not seem to play its role of compressing and assisting the nail plate to grow outward. Hence, it may be that the absence of a proper nail bed, rather than the absence of a proximal nail fold, promotes upward growth of a nail plate instead of outward growth.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
10/31. Unilateral linear psoriasis with palmoplantar, nail, and scalp involvement.Linear psoriasis is a rare entity. It is commonly confused clinically and histopathologically with verrucous epidermal nevus. We report a child who had linear psoriasis in a unilateral distribution with palmoplantar, nail, and scalp involvement.- - - - - - - - - - ranking = 5keywords = palm (Clic here for more details about this article) |
| | Next -> |