1/37. Catastrophic arterial reactivity during primary antiphospholipid syndrome--a case report.Arterial reactivity leading to acute thrombosis at the site of a needle stick injury has never been described during antiphospholipid syndrome. The authors report a case characterized by a succession of thrombotic events occurring during or immediately after arterial angiographies or arterial surgery, in which catastrophic arterial reactivity can be strongly suspected. In this particular patient, it can be postulated that damage to the endothelial cells of the vessels injured during manipulation may have precipitated or aggravated the preexisting susceptibility to thrombosis.- - - - - - - - - - ranking = 1keywords = injury (Clic here for more details about this article) |
2/37. Transient detection of plasma hiv-1 rna during postexposure prophylaxis.Transient plasma human immunodeficiency virus (HIV) copies were detected by nucleic-acid sequence-based amplification during combination antiretroviral prophylaxis in a healthcare worker who reported a percutaneous injury from a stylet and who remained HIV-antibody-negative. An HIV-specific T-helper response, assessed by interleukin-2 production, was observed when tested at 13 months following the exposure.- - - - - - - - - - ranking = 1keywords = injury (Clic here for more details about this article) |
3/37. Potential role of famciclovir for prevention of herpetic whitlow in the health care setting.Oral famciclovir was initiated in a health care worker immediately after an accidental percutaneous injury involving a needle freshly removed from a patient's herpes labialis vesicles. In follow-up, the health care worker remained seronegative for herpes simplex I and II antibodies (IgG and IgM) and did not develop herpetic whitlow, supporting the potential role of famciclovir in the prevention of herpetic whitlow in a health care setting.- - - - - - - - - - ranking = 1keywords = injury (Clic here for more details about this article) |
4/37. Lack of seroconversion in a health care worker after polymerase chain reaction-documented acute hepatitis c resulting from a needlestick injury.We present a case of documented acute hepatitis c that occurred in a health care worker who sustained a needlestick injury while caring for an individual who was infected with both hepatitis c virus (HCV) and human immunodeficiency virus (HIV). According to the findings of third-generation serological assays performed during a follow-up of >1 year, the health care worker, who was treated with interferon-alpha (during weeks 2-6) and ribavirin (during weeks 5-9), did not develop antibodies against HCV, in spite of documentation of an HCV-specific T cell response.- - - - - - - - - - ranking = 5keywords = injury (Clic here for more details about this article) |
5/37. spinal cord injury caused by direct damage by local anaesthetic infiltration needle.We describe a case of spinal cord injury caused by direct trauma from a local anaesthetic infiltration needle. During local anaesthetic infiltration before placement of an epidural catheter, the patient suddenly rolled over onto her back, causing the infiltrating needle to advance all the way to its hub. She immediately showed signs of spinal cord injury, confirmed by MRI scan. However, her neurological status gradually improved, and on discharge she was able to walk, with a sensory deficit localized to her left foot.- - - - - - - - - - ranking = 6keywords = injury (Clic here for more details about this article) |
6/37. Seroconversion to hiv-1 following a needlestick injury despite combination post-exposure prophylaxis.post-exposure prophylaxis with antiretroviral drugs for at-risk needlestick injuries has become routine practice and is usually empirical. With increasing numbers of treatment-experienced patients, the choice of antiretroviral may need to be individually tailored. infection can still occur despite attempts to optimize the drug combination used.- - - - - - - - - - ranking = 4keywords = injury (Clic here for more details about this article) |
7/37. Acute ureteral obstruction following transvaginal oocyte retrieval for IVF.Transvaginal, ultrasound-guided oocyte retrieval has become the gold standard for IVF therapy. Despite a low reported complication rate, here a case is reported of acute ureteral obstruction following seemingly uncomplicated oocyte retrieval. Prompt diagnosis and ureteral stenting led to rapid patient recovery with no long-term urinary tract sequelae. Ureteral injury needs to be included in the differential diagnosis of a patient presenting with pelvic/abdominal pain following oocyte retrieval.- - - - - - - - - - ranking = 1keywords = injury (Clic here for more details about this article) |
8/37. Needlestick transmission of hepatitis c.hepatitis c virus (HCV) transmission following a needlestick is an important threat to health care workers. We present the case of a 29-year-old medical intern who sustained a needlestick injury from a source patient known to be infected with both human immunodeficiency virus and HCV. The case patient subsequently developed acute HCV infection. The optimal strategy for diagnosing HCV infection after occupational exposures has not been defined. At a minimum, HCV antibody and alanine aminotransferase testing should be done within several days of exposure (to assess if the health care worker is already infected with HCV) and 6 months after percutaneous, mucosal, or nonintact skin exposure to blood or infectious body fluids from an HCV-infected patient. Currently, it is not possible to prevent HCV infection after exposure. However, recent data suggest that early treatment of acute HCV infection with interferon alpha may be highly effective in preventing chronic HCV infection. These data underscore the importance of identifying persons with acute HCV infection and promptly referring them to experienced clinicians who can provide updated counseling and treatment.- - - - - - - - - - ranking = 1keywords = injury (Clic here for more details about this article) |
9/37. Transmission of drug-resistant HIV after an occupational exposure despite postexposure prophylaxis with a combination drug regimen.We documented a case of occupational human immunodeficiency virus (HIV) despite postexposure prophylaxis (PEP) with a combination drug regimen after percutaneous injury with a needle from a sharps disposal container in the hospital room of an HIV-infected patient. This failure of PEP with a combination drug regimen may have been related to antiretroviral drug resistance, other factors, or both. This case highlights the importance of preventing injury to prevent occupational transmission of HIV.- - - - - - - - - - ranking = 2keywords = injury (Clic here for more details about this article) |
10/37. Molecular investigation of two possible cases of accidental hiv-1 transmission in south africa.hiv-1 sequences from two possible transmission cases in south africa were examined for evidence of genetic linkage. hiv-1-seropositive blood samples were obtained from a donor and recipient within 8 months following a blood transfusion and from a healthcare worker and her patient within 10 months following a needle-stick injury. A 700-bp region in env and 550-bp region in gag were analyzed. All sequences were phylogenetically associated with hiv-1 subtype C, the predominant hiv-1 subtype in south africa. The nucleotide sequences from the blood transfusion case grouped together significantly with a bootstrap value of 100%. These samples were 98% and 100% identical in the predicted amino acid sequences of env and gag, respectively. In contrast, sequences from the needle-stick case showed only 67% and 80% amino acid identity in env and gag, respectively, and were separated on a phylogenetic tree. Molecular analysis suggested that HIV transmission occurred in the blood transfusion case but not in the case of the needle-stick injury. These data emphasize the need for molecular investigation of epidemiologically linked cases of HIV transmission.- - - - - - - - - - ranking = 2keywords = injury (Clic here for more details about this article) |
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