1/8. Uterine leiomyofibroma associated with mesodermal mixed tumour. Case report.It was reported a case of a 55-year-old woman with giant uterine polylobated leiomyofibromatosis with an albescent-reddish fluctuating nodule, of a mesodermal heterologous mixed tumour aspect. The origin of these sarcomas from mullerian pluripotent mesenchymal cells is discussed. The particularity of this case is underlined by the association of two distinct types of benign and malignant tumours.- - - - - - - - - - ranking = 1keywords = mixed tumour (Clic here for more details about this article) |
2/8. Mixed tumours of the lung: a report of three cases.Three patients with mixed tumours of the lung are presented. The difficulties making a histological diagnosis are stressed and the value of extensive examination of large amounts of tissue, and electron microscopy is emphasized.- - - - - - - - - - ranking = 0.2keywords = mixed tumour (Clic here for more details about this article) |
3/8. Malignant transformation of a benign cutaneous mixed tumour.Whilst benign cutaneous mixed tumour is common, malignant cutaneous mixed tumour is rare. There are only eleven accepted cases of the malignant counterpart in the literature. In none was there residual benign tumour tissue present to suggest that they arose from malignant transformation of the benign tumour. We report a very rare case of a malignant transformation of a benign cutaneous mixed tumour in an eighty-four year old female. Other unusual features in this case included considerable involvement of bone in the primary lesion and the histological picture of extreme pleomorphism and active mitoses, not seen in other reported cases of the malignant tumour.- - - - - - - - - - ranking = 1.4keywords = mixed tumour (Clic here for more details about this article) |
4/8. Embryonic carcinosarcoma (mixed tumour) of the pineal gland.The present paper reports on a pineal gland tumour in an 8-year-old male child. Microscopic examination revealed a carcinomatous and a sarcomatous component. The aspect was characteristic of mixed embryonic carcino-sarcoma described in germ cell layer tumours of the gonads and kidney (Wilms' tumour). Ultrastructurally, the mixed character of the tumour was confirmed and also more differentiated elements were found differing from the appearances described in germ cell layer tumours. On the basis of the morphological examination it is concluded that at least in a proportion of the malignant mixed tumours of the pineal gland, their origin is to be found in the local neural elements and not the extraneural ones.- - - - - - - - - - ranking = 1keywords = mixed tumour (Clic here for more details about this article) |
5/8. Unusual tumours of the lung.Unusual lung tumors are not simply pathological curiosities. They demonstrate features of major significance in diagnosis, treatment, and prognosis. Six of these tumours are discussed: (1) carcinosarcoma is rarely found in the lung. The histogenis of the lesion is unclear and the prognosis is poor. (2) Only three cases of pleomorphic adenoma have previously been described. Differentiation from other "mixed tumours" of the lung is essential. (3) A rare case of bronchial adenoma producing ectopic ACTH is described. Early recognition of these polypeptide hormone-secreting tumours is stressed. (4) Oat cell carcinoma with the myasthenic (Eaton-Lambert) syndrome shows the clinical features which should permit early tumour diagnosis. The hazards of muscle relaxants must be recognized. (5) Prostatic carcinoma with endobronchial metastases is is discussed. The importance of localization of the primary tumour is emphasized. (6) An example of double primary carcinoma is presented. The rarity of this finding may be related to the poor prognosis of patients with bronchogenesis carcinoma.- - - - - - - - - - ranking = 0.2keywords = mixed tumour (Clic here for more details about this article) |
6/8. Is sclerosing hemangioma of lung an alveolar mixed tumour?A case of a peripheral lung tumour histologically categorized as a sclerosing hemangioma of the lung is presented. Ultrastructurally, the tumour is composed of a mixture of epithelial and mesenchymal elements in varying stages of differentiation. Type II pneumocytes are identified as one epithelial component, while primitive mesenchymal cells with a tendency to develop into pericytes are the predominant mesenchymal component. The tumour appears to differentiate along the line of the pulmonary alveolar septa, and should be designated as a 'pulmonary alveolar mixed tumour'.- - - - - - - - - - ranking = 1keywords = mixed tumour (Clic here for more details about this article) |
7/8. Tumours of the Moll's glands.Four cases of tumours arising from Moll's glands, two benign mixed tumours of the skin (chondroid syringomas) and two adenocarcinomas, are reported. Three of the patients were over 40 years old. Contrary to the common assumption that malignant Moll's gland tumours are of low-grade malignancy, the two adenocarcinomas described here were highly malignant. Despite vigorous treatment, including orbital exenteration and lymph node resection, one was rapidly fatal and the other recurred with extensive involvement of the paranasal sinuses.- - - - - - - - - - ranking = 0.2keywords = mixed tumour (Clic here for more details about this article) |
8/8. Malignant germ cell tumours in two siblings.Familial germ cell tumours are well recognised in kinship with gonadal dysgenesis, but their occurrence in siblings with normal chromosomes is rare. We report two sisters who presented within a 4 month period with malignant ovarian germ cell tumours; one a dysgerminoma and the other a mixed tumour with marked choriocarcinomatous elements. Both children had a normal female constitutional karyotype and normal phenotype.- - - - - - - - - - ranking = 0.2keywords = mixed tumour (Clic here for more details about this article) |