1/3. Primitive neuroectodermal tumors of the uterus: a report of four cases.Four cases of primitive neuroectodermal tumor (PNET) of the uterine corpus are reported, bringing the total number of reported PNETs in this site to seven. The four women were in their seventh decade of life and presented with abnormal vaginal bleeding and, in two cases, an enlarged uterus. The patients underwent total or subtotal abdominal hysterectomy and bilateral salpingo-oophorectomy and, in one patient, pelvic lymphadenectomy. Three patients received postoperative radiation therapy, chemotherapy, or both. Gross examination revealed fleshy polypoid masses filling the endometrial cavity and, in two cases, deeply invading the myometrium. Histologic, immunohistochemical, and, in two cases, ultrastructural examination revealed typical PNETs that exhibited variable degrees of neural, glial, ependymal, and medulloepithelial differentiation. Two PNETs were admixed with other neoplasms: in one case a grade I endometrial adenocarcinoma and in the other a low-grade endometrial stromal sarcoma. The prognosis of the tumors was related to their stage: two patients with stage I tumor were alive with no evidence of disease at 5 and 6 years, whereas two patients with stage III or IV tumor died of tumor at 6 and 12 months. Although it has been suggested that uterine PNETs may be derived from displaced germ cells or implanted fetal tissues, evidence provided by this study, including the advanced ages of the patients and an admixture with neoplasms of unquestioned mullerian origin, suggests a mullerian origin for these tumors in at least some cases.- - - - - - - - - - ranking = 1keywords = cavity (Clic here for more details about this article) |
2/3. Benign neurogenic tumors of the oral cavity.Neurogenic tumors are rare in the oral cavity, particularly so when malignant. Traumatic neuroma, although usually included with neurogenic tumors, is a reactive process rather than a true neoplasm. neurofibroma and schwannoma derive from nerve fibers, the perineurium, the endoneurium and the neurolemmomal cells. They present histological differences. The neurofibroma may present in solitary and generalized types; the latter also known as neurofibromatosis or von Recklinghausen's disease of the skin. We here report typical cases of benign neurogenic tumors of the oral cavity.- - - - - - - - - - ranking = 287.82424380296keywords = oral cavity, cavity (Clic here for more details about this article) |
3/3. Neural tumors of the oral cavity. A review of the spectrum of benign and malignant oral tumors of the oral cavity and jaws.The clinical and histologic features of benign and malignant neural tumors of the oral cavity and jaws are reviewed. Some rarer histologic variants are mentioned. Particular attention is paid to the two syndromes involving neural tumors of the oral cavity, namely, neurofibromatosis and multiple endocrine neoplasia III. A previously unreported case of the latter is presented.- - - - - - - - - - ranking = 479.70707300493keywords = oral cavity, cavity (Clic here for more details about this article) |