1/14. Squamous cell carcinoma in chronic ulcerative lesions: a case report and literature review.A case report and literature review are presented involving a fatal case of squamous cell carcinoma of the lower extremity. The unique aspects of this patient include the young age at presentation (35 years old), and the association with both a burn scar (Marjolin's) ulcer and a draining osteomyelitis fistulus tract. Epidemiologic data for Marjolin's ulcers as well as squamous cell carcinoma associated with draining sinus tracts of osteomyelitis are reviewed, in addition to the recommended management of such patients. The case presented is a reminder of the need to maintain a high index of suspicion for malignant transformation within ulcerative lesions.- - - - - - - - - - ranking = 1keywords = carcinoma, squamous cell (Clic here for more details about this article) |
2/14. Burn scar sarcoma.Malignancies developing in burn scars have been known for a long time and are generally epidermoid carcinomas although a few sarcoma cases have been reported. A case of fibrosarcoma developing in the burn scar was presented in this report and the literature reviewed.- - - - - - - - - - ranking = 0.1304661993225keywords = carcinoma (Clic here for more details about this article) |
3/14. Acute squamous cell carcinoma arising within a recent burn scar in a 14-year-old boy.We have described the case of a 14-year-old boy who developed an acute squamous cell carcinoma within a healed burn scar 6 weeks after thermal injury. This is a rare condition necessitating early excision and histopathologic confirmation of clearance. The authors recommend early skin grafting of deep partial- and full-thickness burns to prevent future malignant transformation and a low index of suspicion of any nodules or ulceration appearing within a healed burn.- - - - - - - - - - ranking = 1.195338006775keywords = carcinoma, squamous cell (Clic here for more details about this article) |
4/14. Marjolin's ulcer on the nose.Malignancies in scars are generally known as Marjolin's ulcer. The majority of these arise from burn injuries. Although Marjolin's ulcer consists of all kinds of skin cancer, squamous cell carcinoma is the main cancer type reported in the literature. The pathogenesis of this tumor is due to chronic irritation of the effected area and mostly involves the extremities and scalp area. This report presents an unusually located and rare type of Marjolin's ulcer: on the nose and baso-squamotic in type. A 54-year-old man, 33 years after burn, presented with an unhealed ulcer on his nose which had been present for 2 years. The case was managed by tumor excision and a naso-labial transposition flap. To our knowledge, this is the first report of Marjolin's ulcer developing on post-burned skin of the nose.- - - - - - - - - - ranking = 0.239067601355keywords = carcinoma, squamous cell (Clic here for more details about this article) |
5/14. Aggressive squamous cell carcinoma originating as a Marjolin's ulcer.BACKGROUND: Marjolin's ulcer is an epidermoid carcinoma arising in a scar or chronic wound and can have an aggressive course. OBJECTIVE: To present a case of squamous cell carcinoma arising in a burn scar with resulting metastases and to discuss Marjolin's ulcer. RESULTS: The patient continued to have further metastatic disease despite aggressive surgical treatment. CONCLUSION: In following patients with chronic ulcers and wounds, it is important to evaluate any changes immediately with biopsies and further imaging studies if indicated in order to treat effectively. Even aggressive surgical intervention will sometimes be inadequate in treating these tumors.- - - - - - - - - - ranking = 1.3258042060975keywords = carcinoma, squamous cell (Clic here for more details about this article) |
6/14. dermatofibrosarcoma protuberans arising from a burn scar of the axilla.It is well-known that the development of a malignant tumor in a chronic burn scar is one of the long-term complications of a severe burn. Most of these tumors are squamous cell carcinomas, and sarcomas are much rarely seen in chronic burn scars. In the previous literature, 24 cases of burn scar sarcomas were reported. The authors report the second case of dermatofibrosarcoma protuberans arising in a chronic, severe burn scar. A 68-year-old woman with a reddish tumor in the right axilla was referred to the authors' hospital. The patient had sustained severe burns in the right axilla, upper arm, and trunk at the age of 6 years. A biopsy specimen revealed dermatofibrosarcoma protuberans. There was no evidence of distant metastasis. The tumor was excised widely to include the surrounding burn scar. Two years after the operation, there was no evidence of tumor recurrence. As surgeons, we should recognize the possibility of the occurrence of various malignant tumors including sarcomas on burn scars.- - - - - - - - - - ranking = 0.239067601355keywords = carcinoma, squamous cell (Clic here for more details about this article) |
7/14. Combat injury with chronic osteomyelitis complicated by squamous cell carcinoma.Penetrating injuries of the extremity are common in combat. The patient described in this paper sustained such an injury in vietnam. He exhibited the frequent complication of chronic osteomyelitis and eventually the rare complication of squamous cell carcinoma.- - - - - - - - - - ranking = 1.195338006775keywords = carcinoma, squamous cell (Clic here for more details about this article) |
8/14. Metastatic adenocarcinoma in a recent burn scar.Neoplastic lesions arising in recent burn scars are apparently quite rare and we could find no report of such an occurrence in the literature. Nevertheless we recently treated a patient with a metastatic adenocarcinoma from the lung in a 3-month-old burn scar.- - - - - - - - - - ranking = 0.65233099661249keywords = carcinoma (Clic here for more details about this article) |
9/14. Malignant change in dermatitis artefacta.dermatitis artefacta is a chronic skin lesion produced by self-trauma. Avoidance of further trauma, topical steroids and psychological therapy all play a part in the treatment of such lesions. Unresolved lesions may become large and disfiguring and subject to infection. We report a case of one such lesion in an elderly woman who persistently excoriated a cholecystectomy scar over 40 years. Malignant transformation occurred in a manner analogous to the neoplastic change observed in other types of chronic ulcer (Marjolin's ulcer). The squamous cell carcinoma presented with widespread metastases from which the patient eventually died. Recent literature concerning Marjolin's ulcers is reviewed and it is noted that this is the first reported case of death caused by malignant change in dermatitis artefacta.- - - - - - - - - - ranking = 0.239067601355keywords = carcinoma, squamous cell (Clic here for more details about this article) |
10/14. Marjolin's ulcer of the foot caused by nonburn trauma.Marjolin's ulcers are malignancies that arise from previously traumatized, chronically inflamed, or scarred skin. We report a case of squamous cell carcinoma arising in a foot wound 42 years after the time of injury. The historical background, epidemiology, pathophysiology, diagnosis, treatment, and prognosis of Marjolin's ulcer are reviewed. diagnosis is best accomplished by punch biopsy or excision of suggestive lesions. Wide local excision is required and amputation may be necessary to achieve an adequate margin. Regional lymph node dissection should be done if regional nodes are palpable. Elective lymph node dissection is controversial but should be considered if the tumor is poorly differentiated. lymph node metastases and high tumor grade indicate a poor prognosis. Clinicians should be diligent in the long-term surveillance of all significant scars or areas of chronic inflammation.- - - - - - - - - - ranking = 0.239067601355keywords = carcinoma, squamous cell (Clic here for more details about this article) |
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