1/214. Axillary metastases of an occult primary carcinoma of the breast-discovered only by 99mTc-tetrofosmin scintigraphy.Recent reports consider 99mTc-tetrofosmin scintigraphy to be a powerful new diagnostic tool for discriminating malignant from benign breast disease. We report on a woman suffering from histologically confirmed axillary metastases of a primary unknown, occult carcinoma, whose origin was suspected within the breast. All the diagnostic procedures performed to discover any lesion failed or were inconclusive. The primary cancer was clearly visualized, however, in the right breast by means of 99mTc-tetrofosmin scintigraphy. Conclusion. We suggest that 99mTc-tetrofosmin scintigraphy is a powerful method to detect breast cancer, especially when other diagnostic imaging procedures are inconclusive.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
2/214. Diffuse metastatic infiltration of a carcinoma into skeletal muscle.Skeletal muscle is one of the most unusual sites of metastasis from any malignancy. We report a patient with rapidly progressive contractures due to metastatic infiltration of a carcinoma of unknown origin into the skeletal muscle. This 61-year-old man presented with a 1-month history of rapidly evolving, painful restriction of mobility of his right arm and his legs. Computed tomography showed diffuse metastatic nodules in all muscles, particularly in the hip abductors. Muscle biopsy revealed extensive infiltration of the muscle with carcinoma cells.- - - - - - - - - - ranking = 1.2keywords = carcinoma (Clic here for more details about this article) |
3/214. chylothorax, chylopericardium and lymphoedema--the presenting features of signet-ring cell carcinoma.This report describes a patient with chylous pleural and pericardial effusions in conjunction with severe lymphoedema resembling elephantiasis. The chylous effusions and generalized lymphoedema were associated with a signet-ring cell carcinoma.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
4/214. Cervical metastasis of occult papillary thyroid carcinoma associated with epidermoid carcinoma of the larynx.An occult, laterocervical papillary thyroid carcinoma tissue was found in a functional neck dissection for larynx cancer. The patient was a 76-year-old man with a history of smoking and alcohol ingestion who presented with a supraglottic carcinoma of the larynx located at the laryngeal surface of the epiglottis, left aryepiglottic fold, band and left ventricle with extension to the left vocal cord. light microscopy showed a lymph node with a fibrous stroma with lymphoid follicles that presented a total substitution of the parenchyma by a papillary thyroid carcinoma. Although examination of the thyroid gland by seriated sections did not reveal any neoplasm, we argue that the papillary thyroid tissue is metastatic.- - - - - - - - - - ranking = 2.2keywords = carcinoma (Clic here for more details about this article) |
5/214. pancreaticoduodenectomy for metastatic tumors to the periampullary region.Although operative resection of metastatic lesions to the liver, lung, and brain has proved to be useful, only recently have there been a few reports of pancreaticoduodenectomies in selected cases of metastases to the periampullary region. In this report we present four cases of proven metastatic disease to the periampullary region in which the lesions were treated by pancreaticoduodenectomy. Metastatic tumors corresponded to a melanoma of unknown primary site, choriocarcinoma, high-grade liposarcoma of the leg, and a small cell cancer of the lung. All four patients survived the operation and had no major complications. Two patients died of recurrence of their tumors, 6 and 63 months, respectively, after operation; the other two patients are alive 21 and 12 months, respectively, after operation. It can be inferred from this small but documented experience, as well as a review of the literature, that pancreaticoduodenectomy for metastatic disease can be considered in selected patients, as long as this operation is performed by experienced surgeons who have achieved minimal or no morbidity and mortality with it.- - - - - - - - - - ranking = 0.2keywords = carcinoma (Clic here for more details about this article) |
6/214. Metastatic adenocarcinoma masquerading as basal pontine tuberculoma.Tuberculous infection of the central nervous system is common in hong kong. A 39-year-old woman presented with isolated right sixth nerve palsy which was non-progressive for 10 months. Neuro-imaging revealed a right pontine lesion. cerebrospinal fluid (CSF) examination showed lymphocytic meningitis with negative bacteriological and cytological studies. Empirical antituberculous drugs with initial corticosteroid resulted in improved CSF parameters. A diagnosis of cerebral tuberculoma complicated by meningitis was made. She subsequently deteriorated clinically and radiologically. Despite a number of clinical features which were atypical of leptomeningeal metastasis, adenosquamous carcinoma was found on biopsy. Her relatively indolent clinical course might be due to the initial corticosteroid treatment. This report illustrates the importance of early tissue diagnosis in uncertain cases of chronic lymphocytic meningitis.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
7/214. Diagnostic value of anti-alpha FP antibody levels in a metastatic germ cell tumor of unknown primary site.BACKGROUND: A 21 year old man with a metastatic germ cell tumor of unknown primary not responding to chemotherapy was scheduled to have a blind bilateral orchiectomy to eradicate the possible primary site although palpation and ultrasonography of the testicles had always been normal. METHOD: The patient underwent a radioimmunoscintigraphy with Anti-alpha FP antibody scan (AFP-Scan). RESULTS: On the basis of the scintigraphic results the patient underwent a left orchiectomy and additionally removal of the lymph node metastases. histology revealed the presence of an in situ carcinoma in the left testis and a mixed tumor present in the abdominal lymph node metastases. Fluorescent in situ hybridization on tumor cells did not show any abnormalities related to chromosome 12, a finding connected with the somatic type of germ cell tumors. CONCLUSION: Anti-alpha FP antibody scan was helpful in detecting the primary site and saving the life of the patient without resulting in hypogonadism.- - - - - - - - - - ranking = 0.2keywords = carcinoma (Clic here for more details about this article) |
8/214. Bilateral cerebellopontine metastases in a patient with an unknown primary.We report the case history of a patient who presented with symptoms and signs suggestive of a left cerebellopontine tumour. He underwent an exploratory posterior fossa craniotomy, which revealed metastatic adenocarcinoma. Despite intensive investigation, a primary site was not located and the patient received cranial irradiation. The patient re-presented 2 years later with further symptoms from a metastasis in the right cerebellopontine angle. He refused further intervention.- - - - - - - - - - ranking = 0.2keywords = carcinoma (Clic here for more details about this article) |
9/214. Acrometastasis in renal cell carcinoma.Acrometastasis is rare and may occur as the primary manifestation of an occult malignant tumor. Clinically, it may mimic benign osteoarthritic diseases, thus resulting in misdiagnosis and improper treatment. We describe a patient with renal cell carcinoma that presented itself as a case of chronic osteomyelitis after trauma to a finger. Such a lesion presents diagnostic challenges to both clinicians and histopathologists.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
10/214. Metastatic cancer presenting as TMD. A case report.The dentist's responsibility in managing patients should include the awareness that not every pain in the face is due to a toothache or a temporomandibular disorder (TMD). This paper reviews the case of a 66-year-old patient who presented to the dental office with a chief complaint of unilateral jaw pain. The symptoms seemed consistent with TMD. Two years prior, the patient had undergone successful removal of a cancerous prostate and had remained under urologist care with a favorable prognosis. Subsequent imaging studies confirmed that the facial pain was due to multiple metastatic lesions to areas including the zygoma, infratemporal fossa, maxilla and brain. However, these metastatic lesions were not of prostate origin, but rather were from a squamous cell carcinoma originating in a primary site other than the prostate.- - - - - - - - - - ranking = 0.2keywords = carcinoma (Clic here for more details about this article) |
| | Next -> |