1/3. Amyloid vascular disease and contracted kidneys--report of a case with review of literature.A case of systemic amyloidosis associated with bronchiectasis is presented. At necropsy, contracted kidneys and centrilobular necrosis of the liver were observed. Systemic blood vessels had heavy deposition of amyloid, and the possibility of visceral ischemia and the development of contracted kidneys due to amyloid vascular disease as a pathogenetic relationship, was discussed against the background of a review of the literature.- - - - - - - - - - ranking = 1keywords = vascular disease (Clic here for more details about this article) |
2/3. Acquired renal cysts and multiple renal cell and urothelial tumors.This paper reports two cases of acquired renal cysts and multiple renal cell tumors in end-stage kidneys with a discussion of the pathogenesis of these lesions. The first patient had been on maintenance dialysis for approximately three years when he was found to have multiple renal cysts and renal cell tumors. He subsequently developed multifocal urothelial carcinomas of the lower urinary tract. The second patient had progressive renal failure due to hypertensive vascular disease when he underwent left nephrectomy because of multiple renal cysts and renal cell carcinoma. He later developed terminal renal failure and was maintained on chronic dialysis. He expired three years later. At autopsy, the right kidney also demonstrated multiple cysts and renal cell tumors.- - - - - - - - - - ranking = 0.2keywords = vascular disease (Clic here for more details about this article) |
3/3. Accelerated hypertension and nephroangiosclerosis associated with antiphospholipid syndrome. Report of two cases and review of the literature.We describe two patients with the primary antiphospholipid syndrome who presented with severe hypertension. Renal biopsy specimen provided histologic evidence of intra-renal vascular disease with intravascular microthrombosis and nephrosclerosis, without feature of proliferative glomerulopathy. Accelerated hypertension and nephroangiosclerosis might indeed be one of the complications associated with anticardiolipin antibodies. The mechanism responsible might be the interaction of anticardiolipin antibodies, platelets and endothelial cell leading to microthrombi formation and increased local mitogenic activity that attract and stimulate neighbouring smooth muscle cell and fibroblast proliferation.- - - - - - - - - - ranking = 0.2keywords = vascular disease (Clic here for more details about this article) |