1/24. Cervical sympathetic chain schwannomas masquerading as carotid body tumors.Cervical sympathetic chain (CSC) schwannoma is a rare neurogenic tumor that can mimic a carotid body tumor (CBT). Two male patients aged 33 and 49 years old were referred for a cervical mass thought to be a CBT. Both patients were found to have an asymptomatic, pulsatile, nontender mass located at the level of the angle of the mandible. Both patients were neurologically asymptomatic and cranial nerves were normal. Both patients underwent neck exploration and resection of the mass involving the CSC. Postoperatively, a Horner's syndrome was present. Histopathology confirmed both tumors to be schwannomas of the CSC. At follow-up, both patients are asymptomatic with no recurrence. The main imaging criterion to differentiate a CBT from a CSC schwannoma is the lack of hypervascularity of the latter. Malignant transformation is extremely rare. Tumor excision gives excellent results with no local recurrence. Horner's syndrome is an expected postoperative complication.- - - - - - - - - - ranking = 1keywords = schwannoma (Clic here for more details about this article) |
2/24. Ancient schwannoma masquerading as a thyroid mass.Schwannomas are benign, encapsulated nerve sheath cell neoplasms. Cervical sympathetic chain (CSC) schwannomas are rare, with less than 50 cited cases in the literature. CSC schwannomas may mimic a number of parapharyngeal masses. We report a rare variant, "ancient" schwannoma, which presented cytologically and radiologically as a thyroid mass. This is the first report of a CSC schwannoma mimicking a thyroid mass and the first report of an ancient schwannoma of the CSC.- - - - - - - - - - ranking = 1.2857142857143keywords = schwannoma (Clic here for more details about this article) |
3/24. Sacrococcygeal ganglioneuroma.Ganglioneuromas are benign slow-growing masses that can be treated with complete surgical extirpation without any adjuvant therapy. Such lesions involving the sacrococcygeal region are exceedingly rare. The authors present the case of a 70-year-old woman with a sacrococcygeal ganglioneuroma treated by total en bloc resection. This patient also had a previous coccygeal fracture. To the authors' knowledge, there are no other reports of ganglioneuroma in association with a history of trauma.- - - - - - - - - - ranking = 0.19951360089963keywords = neuroma (Clic here for more details about this article) |
4/24. An unusual presentation of a rare nerve cell tumour.We present a rare case of a schwannoma in a pre/para-aortic position resembling a thrombosed saccular abdominal aortic aneurysm.- - - - - - - - - - ranking = 0.14285714285714keywords = schwannoma (Clic here for more details about this article) |
5/24. ganglioneuroma : primary tumor or maturation of a suspected neuroblastoma?ganglioneuroma is a benign neurogenic tumor. These tumors are originating from neuroepithelium along sympathetic ganglia. Main localization is the mediastinum in children older than 10 years. An association with malignant neuroblastoma is rarely observed and it still remains a topic under current discussion. We describe the clinical course of a 17 year-old female patient with a large presacral mass causing amenorrhoea and weight loss. Eleven years before presentation, an incidental urine test showed an elevation of vanillylmandelic acid (VMA) and homovanillic acid (HMA) and a neuroblastoma was suspected. However, further investigations showed no tumor and the test results turned out to be normal within 1 year. Now, a malignant neurogenic tumor was again suspected, but a CT-guided biopsy revealed a benign tumor. The mass was originating from the left sacral nerve roots. A tumor resection via a dorsal approach was performed. Final histology showed a differentiated ganglioneuroma. This is, to our knowledge, the first report describing a patient with elevated VMA/HMA and suspected neuroblastoma who developed a ganglioneuroma 11 years later. The association of ganglioneuroma and neuroblastoma and the abnormal urine tests pointing toward a neuroblastoma 11 years ago remains unclear and the possible answers are discussed in our report.- - - - - - - - - - ranking = 0.22801554388529keywords = neuroma (Clic here for more details about this article) |
6/24. Digital pacinian corpuscle neuroma eroding bone: a case report.A case of digital pacinian corpuscle neuroma leading to erosive changes in the adjacent proximal phalanx is reported. Characteristics and previous reports of this relatively uncommon hand tumor are discussed.- - - - - - - - - - ranking = 0.14250971492831keywords = neuroma (Clic here for more details about this article) |
7/24. Occurrence of both neurofibromatoses 1 and 2 in the same individual with a rapidly progressive course.We describe a family in which the father had neurofibromatosis-1 and the mother neurofibromatosis-2. Their son presented at the age of 8 years with bilateral acoustic neuromas, meningioma, and numerous neurofibromas. We believe that the occurrence of the genes responsible for both forms of neurofibromatosis in the same patient had a synergistic effect on the early rapid growth of neurofibromatoses 1 and 2 neoplasms.- - - - - - - - - - ranking = 0.028501942985661keywords = neuroma (Clic here for more details about this article) |
8/24. Schwannomatosis. An unusual variant of neurofibromatosis or a distinct clinical entity?Multiple schwannomas have frequently been seen in patients with neurofibromatosis. Recently, the association of multiple cutaneous schwannomas, central nervous system tumors, and various neurologic deficits has been described in Japanese patients as a condition called schwannomatosis. We describe the first non-Japanese cases of schwannomatosis and compare and contrast this unusual condition with the well-known variants of neurofibromatosis. We conclude that the features of schwannomatosis are distinct and define a condition that does not fit into the current classification scheme of neurofibromatosis. The occurrence of multiple cutaneous schwannomas in the absence of cardinal features of neurofibromatosis may indicate the presence of central nervous system tumors or various neurologic deficits.- - - - - - - - - - ranking = 0.85714285714286keywords = schwannoma (Clic here for more details about this article) |
9/24. Two epithelioid malignant schwannomas in a patient with neurofibromatosis. Cytology, histology and dna-flow-cytometry.Cytological, histological and dna-ploidy findings of 2 epithelioid malignant schwannomas arising in a patient with von Recklinghausen's neurofibromatosis are described. In both primary tumors, i.e. in the thigh and in the thoracic wall, origin from a neurofibromatous nerve could be established. Within 2 years after the manifestation of the first malignant tumor the patient died of widely metastasized disease. dna-flow cytometry of several neurofibromas revealed diploid stemlines, but both malignant primary tumors and a lung metastasis appeared to be aneuploid. Presumably, the primary tumors also contained cell populations with a diploid stem line.- - - - - - - - - - ranking = 0.71428571428571keywords = schwannoma (Clic here for more details about this article) |
10/24. Quantitative study of radioiodinated metaiodobenzylguanidine uptake in children with neuroblastoma: correlation with tumor histopathology.Six children with neuroblastoma and one with ganglioneuroma received [125I] metaiodobenzylguanidine (MIBG) before major surgery. Uptake of [125I]MIBG in the excised tissues was measured by scintillation counting, and the material was submitted for histopathology. The ranges of uptake of [125I]MIBG, expressed as percent of the injected dose per gram of tissue, were as follows: for neuroblastoma 0.0013-0.071, for ganglioneuroma 0.0017-0.0028, and for non-neoplastic control tissues 0.0002-0.011. The quantitative uptake of [125I]MIBG by neuroblastoma varied between different patients and between different parts of individual tumors. The more undifferentiated tumors took up more [125I]MIBG and may be more likely to respond to targeted radiotherapy with MIBG.- - - - - - - - - - ranking = 0.057003885971323keywords = neuroma (Clic here for more details about this article) |
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