1/10. Lichen simplex chronicus of the eyelid.Lichen simplex chronicus is a common dermatosis that rarely affects the eyelids. We report the clinical and pathologic features in the case of a middle-aged man who had lichen simplex chronicus of both lower eyelids. The clinical features suggested the presence of basal cell carcinoma.- - - - - - - - - - ranking = 1keywords = simplex (Clic here for more details about this article) |
2/10. strongyloides stercoralis infection presenting as generalized prurigo nodularis and lichen simplex chronicus.strongyloides stercoralis is a parasitic nematode that develops an autoinfective life cycle within the gastrointestinal tract of its human host. The infection produces peripheral eosinophilia and cutaneous eruptions, as well as gastrointestinal or respiratory symptoms. Detection of S stercoralis is difficult through stool examination, but may be demonstrated by ELISA for IgG antibody against the parasite. We describe a patient with chronic S stercoralis infection initially presenting with generalized prurigo nodularis and lichen simplex chronicus.- - - - - - - - - - ranking = 0.83333333333333keywords = simplex (Clic here for more details about this article) |
3/10. lupus vulgaris mimicking lichen simplex chronicus.Cutaneous tuberculosis is not an uncommon entity but it often remains undiagnosed and is inappropriately treated due to its varied presentation. We present a 42-year-old male with lupus vulgaris in the perianal area, who was treated as lichen simplex chronicus with steroids for two years. With four drug antitubercular treatment, the patient had a dramatic response. The case is being reported because in this hiv era with the resurgence of tuberculosis, not only will there be an increase in incidence but also more involvement of atypical sites.- - - - - - - - - - ranking = 0.83333333333333keywords = simplex (Clic here for more details about this article) |
4/10. Unilateral, circumscribed, chronic dermatitis of the papillary-areolar complex: case report and review of the literature.Lichen simplex chronicus is a well-described, common pruritic disorder resulting from repeated rubbing and scratching. Typically, only one site is involved. When this site involves the papillary-areolar complex of one breast, the condition is termed unilateral, circumscribed, chronic dermatitis of the papillary-areolar complex. A patient with this uncommon condition is herein reported, and the literature, including a discussion of the differential diagnosis, is reviewed. An aggressive approach to the work-up of such a patient is recommended, to ensure accurate diagnosis and initiation of appropriate therapy.- - - - - - - - - - ranking = 0.16666666666667keywords = simplex (Clic here for more details about this article) |
5/10. Unusual case presentation of lichen simplex chronicus, Hodgkin's lymphoma, and nonpuerperal hyperprolactinemia-galactorrhea.OBJECTIVE: To report the association of nonpuerperal galactorrhea and severe pruritus with clinical stage IIB Hodgkin's lymphoma. methods: We present a detailed history, findings on physical examination, laboratory data, and results of diagnostic imaging in a 25-year-old woman. A review of the related literature and speculations about possible etiologic factors for this association are provided. RESULTS: Dermatologic evaluation of the patient revealed lichen simplex chronicus with multiple excoriations on the anterior chest area and lower extremities. High serum prolactin concentrations and easily expressible galactorrhea were present. magnetic resonance imaging of the sella with 1-mm cuts, however, revealed a normal pituitary gland. Computed tomography showed multiple enlarged mediastinal lymph nodes, and a left supraclavicular lymph node biopsy revealed the presence of reed-sternberg cells and lymphocyte alterations consistent with the diagnosis of Hodgkin's lymphoma. After one cycle of chemotherapy for management of the lymphoma, parallel reductions in serum prolactin concentrations and galactorrhea were noted. CONCLUSION: Possible causes for this syndrome include afferent mammary nerve stimulation resulting from scratching of pruritic skin and cytokine-induced hypersecretion of prolactin attributable to the lymphoma. Although uncommon, this syndrome may serve as an important harbinger of developing Hodgkin's lymphoma, and its disappearance may signify a therapeutic response.- - - - - - - - - - ranking = 0.83333333333333keywords = simplex (Clic here for more details about this article) |
6/10. The simplex (differentiated) variant of vulvar intraepithelial neoplasia.BACKGROUND: The simplex (differentiated) variant of vulvar intraepithelial neoplasia is rarely reported. It is regarded as more likely than "classic" carcinoma in situ to be associated with invasion and can be easily mistaken for benign lesions. OBJECTIVE: The objective was to present a case of simplex variant of vulvar intraepithelial neoplasia in a 67-year-old woman that was initially misdiagnosed as lichen simplex chronicus. methods: A case report is reported and the literature is reviewed. RESULTS: Surgical excision with a free margin of 5 mm was performed and no evidence of recurrence was noted during the follow-up period of 6 months. CONCLUSION: The simplex vulvar intraepithelial neoplasia is an easily overlooked premalignant disease, and it can be cured with surgical treatment if diagnosed correctly and early.- - - - - - - - - - ranking = 1.3333333333333keywords = simplex (Clic here for more details about this article) |
7/10. Allergic contact dermatitis from hair dye and development of lichen simplex chronicus.Those who dye their hair frequently manifest allergic contact dermatitis (ACD) from p-phenylenediamine (PPD)-containing hair dye. PPD is known to be the most frequent sensitizer in hair dye, but there has been no documentation of this sensitizer having a role in chronic dermatologic conditions. Our department experienced a case of a 62-year-old woman with lichen simplex chronicus (LSC), who complained of aggravation after hair dyeing and made such an association. We conducted a prospective and retrospective study to further evaluate the clinical associations between the two. In our prospective study, patch testing was performed in selected patients who regularly carried out hair dyeing and also had clinical manifestations of LSC. Also a retrospective examination was conducted in cases where patch testing had been performed with PPD in the past for suspected ACD and further selected cases with concurrent LSC and/or other neurodermatitis. 11 and 14 patients in our prospective and retrospective study, respectively, presented with both LSC and positive findings to PPD. 5 (45.5%) and 4 (28.6%) patients in our prospective and retrospective study showed clinical relevance from clinical improvement after stopping use and rechallenge. We report several cases of patients diagnosed as having LSC and/or prurigo nodularis who showed clinical improvement after discontinuing the use of hair dye. The suggestion can therefore be made that hair dye could be a possible aetiologic agent causing LSC in those using hair dyes.- - - - - - - - - - ranking = 0.83333333333333keywords = simplex (Clic here for more details about this article) |
8/10. Lichen simplex chronicus as the initial manifestation of intramedullary neoplasm and syringomyelia.Neurogenic causes of pruritus and a rash are uncommon. We report a patient with dermatomal pruritus and a rash who had a cervicothoracic syrinx and a thoracic spinal cord tumor. We believe the syrinx interrupted fibers subserving itch, resulting in dermatomal pruritus with secondary scratching and a rash.- - - - - - - - - - ranking = 0.66666666666667keywords = simplex (Clic here for more details about this article) |
9/10. Lichen simplex chronicus during lithium treatment.A patient who was taking lithium developed an intensely pruritic lesion that remitted after lithium discontinuation and recurred with readministration. The condition was successfully treated with local steroid application, which permitted continuation of lithium maintenance.- - - - - - - - - - ranking = 0.66666666666667keywords = simplex (Clic here for more details about this article) |
10/10. Localized cutaneous amyloidosis simulating lichen simplex chronicus.We report a case of localized cutaneous amyloidosis in a 42-year-old Japanese woman. skin lesions were confined to the nuchal area, and the clinical appearance resembled that of lichen simplex chronicus. Our experience with this case indicates that, in cases presenting with persistent skin lesions simulating lichen simplex chronicus, amyloid should be specifically looked for in biopsy material.- - - - - - - - - - ranking = 1keywords = simplex (Clic here for more details about this article) |
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