1/22. The management of patients with the kasabach-merritt syndrome.The kasabach-merritt syndrome comprises consumption coagulation associated with giant haemangioma. A case is reported of disseminated intravascular coagulation complicating dental extraction in a 36-year-old male with this syndrome. The pre-operative management with anticoagulant therapy is discussed and the relevant literature reviewed.- - - - - - - - - - ranking = 1keywords = intravascular coagulation, coagulation, intravascular (Clic here for more details about this article) |
2/22. disseminated intravascular coagulation and fibrinolysis as a cause of postextraction hemorrhage. Report of a case.Presented is a case in which severe, prolonged hemorrhage, subsequent to simple dental extractions in an 85-year-old Negro man, was due to disseminated intravascular coagulation, with secondary fibrinolysis resulting from metastatic adenocarcinoma of the prostate gland. The difficulty and delay in diagnosis, selection of proper therapeutic regimen, and complications encountered during treatment are discussed.- - - - - - - - - - ranking = 4.2962999355321keywords = intravascular coagulation, coagulation, intravascular (Clic here for more details about this article) |
3/22. quinine induced coagulopathy--a near fatal experience.A 67 year old man presented to his local dentist for restorative treatment. He stated he was fit and well and denied taking any medications. When he was given an inferior alveolar nerve block, excessive bleeding was noted at the injection site and the dentist advised the patient see an oral and maxillofacial surgeon. An appointment was made for the patient but he did not attend. Three days later, he presented with evidence of massive deep haemorrhage to the point of airway compromise. He underwent hospital admission, early intubation, intensive care for nine days and hospitalization for six weeks. The cause of his bleeding was a severe thrombocytopoaenia, induced by chronic ingestion of quinine. He was self-medicating with this to relieve muscular cramps. Despite this experience, the patient continued to deny that quinine was the cause of his problem and that he had failed in his obligations to advise the dentist of his drug history. dentists need to be alert to the risk that patients may not reveal their true medical history. There are, however, obligations on the dentist to ensure the accuracy of information the patient gives and to ensure that patients whom they believe are at risk follow their advice. Teamwork and skillful airway management prevented this patient's demise.- - - - - - - - - - ranking = 0.87155116592428keywords = coagulopathy (Clic here for more details about this article) |
4/22. Infra red coagulation for bleeding mucosal telangiectasia.The technique of infra red coagulation is well suited to the destruction of superficial blood vessels in the skin and/or mucosal surfaces. A method is described here for the destruction of resistant bleeding telangiectasia of the palate and lip in Osler-Weber-Rendu syndrome.- - - - - - - - - - ranking = 0.70370006446786keywords = coagulation (Clic here for more details about this article) |
5/22. Occult hemophilia: prolonged bleeding follows extraction.A 51-year-old man had delayed and recurrent bleeding after tooth extractions. Occult hemophilia b was discovered. This case emphasizes the importance of evaluating patients for an underlying coagulopathy when bleeding greater than expected occurs. In this case, the patient had no personal or family history of bleeding.- - - - - - - - - - ranking = 0.21788779148107keywords = coagulopathy (Clic here for more details about this article) |
6/22. Disseminated intravascular coagulopathy: manifestations after a routine dental extraction.Clinical signs and symptoms of acute disseminated intravascular coagulopathy (DIC) include bleeding from body orifices, such as the nose, mouth, or ear, bleeding from an intravenous (IV) site, areas of ecchymosis, or blood in the urine or stool. The underlying disease triggering DIC usually determines the clinical presentation. However, patients with chronic DIC (compensated DIC) may possess subclinical signs and symptoms, and the bleeding disorder may only be identified through laboratory findings. In this compensated form, the triggering factor is exposed slowly and in small amounts (seen in malignancies and vasculitis), allowing replenishing of the augmented factors by the liver, adequate reticuloendothelial clearance of fibrin degradation products, and increased production of platelets, which prevent secondary fibrinolysis and the signs of bleeding. 1,4 We report a case of an 82-year-old male who presented to the emergency room 24 hours after a routine dental extraction with bleeding from the tooth socket, severe hypotension, and presence of ecchymosis on his chest. Clinical and radiographic exam revealed multiple thoracic and abdominal aortic aneurysms, as well as infrarenal and iliac aneurysms, continuous oral hemorrhage, and a unique presentation rarely documented in the literature: a bleeding tooth socket as the initial clinical sign and presentation of DIC.- - - - - - - - - - ranking = 1.3859311891801keywords = coagulopathy, intravascular (Clic here for more details about this article) |
7/22. Management of bleeding in a multi-transfused patient with positive HLA class I alloantibodies and thrombocytopenia associated with platelet dysfunction refractory to transfusion of cross-matched platelets.thrombocytopenia is a common condition in the critical care setting. Repetitive platelet transfusion might lead to formation of alloantibodies. HLA class I and human platelet antigen antibodies can lead to transfusion-refractory thrombocytopenia. Transfusion of cross-matched platelets often is effective in these patients. We report on the successful use of recombinant activated factor VII in an acute bleeding situation in a multi-transfused patient presenting with positive HLA class I alloantibody status and thrombocytopenia associated with platelet dysfunction refractory to even transfusion of cross-matched platelets. The 41-year-old female patient developed HLA class I antibodies during former episodes of massive transfusion. Her former medical history was empty concerning hemorrhagic events. During this specific bleeding episode the patient suffered from intractable profuse bleeding from the nasopharynx and oral cavity. Global coagulation tests were within the normal range. Platelet dysfunction was confirmed by PFA100. Initially the patient responded well to Desmopressin infusion, but after 36 h she became thrombocytopenic and refractory to even transfusion of cross-matched platelets. Recombinant activated factor VII was chosen as the last resort. Two identical boli of 160 microg/kg NovoSeven each were injected via a central line within an interval of 3 h. After the first injection bleeding was significantly reduced and vasopressor support discontinued. After the second bolus bleeding completely ceased and did not reoccur. We did not observe any side effects. The pluripotent hemostatic agent recombinant activated factor VII might be a new option in the treatment of hemorrhagic episodes in patients presenting with this rare disorder, especially when the patient is refractory to cross-matched platelets or matched platelets are not available.- - - - - - - - - - ranking = 0.14074001289357keywords = coagulation (Clic here for more details about this article) |
8/22. factor xi deficiency disclosed following haemorrhage related to a dental extraction. Brief review and case report.factor xi deficiency is a relatively common hereditary coagulation disorder manifested generally as diffuse oozing from a surgical site. dentists may be the first to discover this deficiency and other coagulopathies after simple tooth extraction. A case is reported which illustrates a typical presentation of this disorder. The need for haematological examination and special dental care is discussed.- - - - - - - - - - ranking = 0.14074001289357keywords = coagulation (Clic here for more details about this article) |
9/22. Spontaneous postpartum factor viii inhibitor development with bleeding into the face and neck.The coagulopathy caused by factor viii inhibitor development can cause life-threatening bleeding that may be difficult to manage. Control of the bleeding, medically and surgically, and normalization of factor viii and inhibitor levels are the goals of treatment; several modes of therapy are available. A case of spontaneous post-partum development of factor viii inhibitors was presented and discussed.- - - - - - - - - - ranking = 0.21788779148107keywords = coagulopathy (Clic here for more details about this article) |
10/22. Upper airway obstruction secondary to warfarin-induced sublingual hematoma.Sublingual hematoma is a rare but potentially fatal complication of oral warfarin sodium. Less than ten cases are reported in the English-language literature with only two of these appearing in the otolaryngologic literature. Spontaneous bleeding into the sublingual and submaxillary spaces creates a "pseudo-Ludwig's" phenomenon with elevation of the tongue and floor of mouth and subsequent airway compromise. Two new cases, along with a review of the literature are presented. Management is directed at prompt control of the airway and reversal of the coagulopathy. Sore throat is a uniform, early complaint that should be taken seriously in any patient receiving oral anticoagulation therapy.- - - - - - - - - - ranking = 0.35862780437464keywords = coagulopathy, coagulation (Clic here for more details about this article) |
| | Next -> |