1/8. Acute idiopathic thrombocytopenic purpura in childhood: a case report.Acute thrombocytopenic purpura is the most common of thrombocytopenias of the childhood. Clinical features include petechial lesions on oral mucosa, gingival bleeding and occasionally hemorrhage. A case of acute thrombocytopenic purpura is presented.- - - - - - - - - - ranking = 1keywords = thrombocytopenic, purpura (Clic here for more details about this article) |
2/8. Dentoalveolar trauma in a patient with chronic idiopathic thrombocytopenic purpura: a case report.A case is presented of a 13-year-old boy with chronic idiopathic thrombocytopenic purpura (ITP) who sustained traumatic labial luxation of both lower central incisors, with partial alveolar fracture resulting in displacement of the labial alveolar plate. Intravenous immunoglobulin (Fleibogamma, 1 g/kg body weight x 2 days) was administered, resulting in the patient's platelet count rising from 15,000/mm3 to 70,000/mm3. Under general anesthesia, the displaced lower labial alveolus and luxated teeth were repositioned and splinted 2 days following trauma. Healing was uneventful. Subsequently, both lower central incisors became nonvital and were endodontically treated. The dental treatment of this patient with ITP is discussed in terms of emergency management, and subsequent care.- - - - - - - - - - ranking = 0.83333333333333keywords = thrombocytopenic, purpura (Clic here for more details about this article) |
3/8. Management of bleeding in a multi-transfused patient with positive HLA class I alloantibodies and thrombocytopenia associated with platelet dysfunction refractory to transfusion of cross-matched platelets.thrombocytopenia is a common condition in the critical care setting. Repetitive platelet transfusion might lead to formation of alloantibodies. HLA class I and human platelet antigen antibodies can lead to transfusion-refractory thrombocytopenia. Transfusion of cross-matched platelets often is effective in these patients. We report on the successful use of recombinant activated factor vii in an acute bleeding situation in a multi-transfused patient presenting with positive HLA class I alloantibody status and thrombocytopenia associated with platelet dysfunction refractory to even transfusion of cross-matched platelets. The 41-year-old female patient developed HLA class I antibodies during former episodes of massive transfusion. Her former medical history was empty concerning hemorrhagic events. During this specific bleeding episode the patient suffered from intractable profuse bleeding from the nasopharynx and oral cavity. Global coagulation tests were within the normal range. Platelet dysfunction was confirmed by PFA100. Initially the patient responded well to Desmopressin infusion, but after 36 h she became thrombocytopenic and refractory to even transfusion of cross-matched platelets. Recombinant activated factor vii was chosen as the last resort. Two identical boli of 160 microg/kg NovoSeven each were injected via a central line within an interval of 3 h. After the first injection bleeding was significantly reduced and vasopressor support discontinued. After the second bolus bleeding completely ceased and did not reoccur. We did not observe any side effects. The pluripotent hemostatic agent recombinant activated factor vii might be a new option in the treatment of hemorrhagic episodes in patients presenting with this rare disorder, especially when the patient is refractory to cross-matched platelets or matched platelets are not available.- - - - - - - - - - ranking = 0.12210213947446keywords = thrombocytopenic (Clic here for more details about this article) |
4/8. Mega-dose intravenous methylprednisone for the treatment of onyalai: a case report.Onyalai, a peculiar manifestation of idiopathic thrombocytopenic purpura characterized by a haemorrhagic bullae of the oral mucosa and lips, was diagnosed in a 1.5-month-old Turkish boy. He was treated with mega-dose intravenous methylprednisolone (30 mg/kg for 3 days) with prompt platelet response and improvement of oral mucosal findings.- - - - - - - - - - ranking = 0.16666666666667keywords = thrombocytopenic, purpura (Clic here for more details about this article) |
5/8. Dental considerations in the treatment of wiskott-aldrich syndrome: report of case.This disease is characterized by cutaneous eczema (usually beginning on the face), thrombocytopenic purpura, and an increased susceptibility to infection due to an immunologic defect. oral manifestations include gingival bleeding and palatal petechiae. Hyperplastic gingiva may now be expected as a complication of cyclosporine A therapy.- - - - - - - - - - ranking = 0.16666666666667keywords = thrombocytopenic, purpura (Clic here for more details about this article) |
6/8. Thrombocytopenic purpura secondary to quinidine hypersensitivity.A case of quinidine-induced thrombocytopenic purpura is reported. The patient had been previously sensitized and developed oral bleeding. On repeated ingestion of the drug, he developed classic oral manifestations of the hemorrhagic disease and sought dental treatment. Identification and withdrawal of the drug reversed the clinical and hematologic symptoms.- - - - - - - - - - ranking = 0.34492477543548keywords = thrombocytopenic, purpura (Clic here for more details about this article) |
7/8. Acute idiopathic thrombocytopenic purpura.A 35-year-old man had hemorrhagic bullae of the buccal and sublingual mucosa as the first sign of acute idiopathic thrombocytopenic purpura. Twenty-four hours later the more typical cutaneous manifestations of petechiae of the lower extremities were present. Although it is unusual for the initial symptoms of this disease to be limited to the oral region, the physician and dentist should be keenly aware of the clinical appearance described in this article, as it may be the only clue of an underlying systemic disease.- - - - - - - - - - ranking = 0.83333333333333keywords = thrombocytopenic, purpura (Clic here for more details about this article) |
8/8. Acute idiopathic thrombocytopaenic purpura in childhood: report of a case presenting in general dental practice.Acute idiopathic thrombocytopaenic purpura is the most common of the thrombocytopaenias of childhood. Clinically it is associated with petechiae, mucocutaneous bleeding and occasionally haemorrhage into tissues. The oral mucosa is frequently involved. This paper describes a case presenting in general dental practice.- - - - - - - - - - ranking = 0.22282263596102keywords = purpura (Clic here for more details about this article) |