1/4. swine influenza virus infections. Transmission from ill pigs to humans at a wisconsin agricultural fair and subsequent probable person-to-person transmission.In September 1988, a previously healthy 32-year-old pregnant woman was hospitalized for pneumonia and died 8 days later. The only pathogen detected was an influenza virus antigenically related to the swine influenza virus (SIV). Four days before illness onset, the patient visited a county fair swine exhibition where there was widespread influenzalike illness among the swine. To detect other persons who were possibly infected by contact with the ill swine, we measured serum SIV hemagglutination-inhibition antibody titer in 25 swine exhibitors who were 9 to 19 years old. Nineteen (76%) had SIV hemagglutination-inhibition titers of 20 or greater. Antibody was undetectable in serum samples from 25 swine exhibitors from a neighboring county. Additional studies suggest that one to three health care personnel who had contact with the patient developed influenzalike illnesses with laboratory evidence of SIV infection. An outbreak of apparent SIV infection in swine resulted in multiple human infections, and, although no recognized community outbreak resulted, there was evidence of virus transmission from the patient to health care personnel.- - - - - - - - - - ranking = 1keywords = swine (Clic here for more details about this article) |
2/4. Fatal swine influenza pneumonia during late pregnancy.Serious morbidity or death from swine influenza infection is unusual in the immunocompetent host. We present a fatal case of pneumonia caused by this virus in a previously healthy 32-year-old woman during her third trimester of pregnancy, and review all published case reports of swine influenza in united states civilians. pregnancy may be a predisposing factor to fulminant infection with swine influenza virus.- - - - - - - - - - ranking = 1keywords = swine (Clic here for more details about this article) |
3/4. Sporadic occurrence of zoonotic swine influenza virus infections.Two infections by swine influenza virus, antigenically similar to A/new jersey/76 (H1N1) virus, were detected during community epidemics with other influenza viruses. The swinelike viruses were obtained during virological surveillance of acute respiratory illnesses, and the clinical symptoms of these two patients were similar to those caused by other respiratory viruses. Both patients reported contact with swine a few days before onset of illness, but in one case it was brief. Serological studies suggested that one patient may have transmitted the virus to his roommate, but spread into the community was not indicated.- - - - - - - - - - ranking = 1keywords = swine (Clic here for more details about this article) |
4/4. Lack of significant person-to-person spread of swine influenza-like virus following fatal infection in an immunocompromised child.In February 1982, a four-year-old nevada girl with acute lymphoblastic leukemia in remission was hospitalized with fulminant pneumonia and died eight days later at a hospital in california. An influenza virus was the only pathogen detected, and was present in both antemortem and postmortem specimens. The virus was closely related antigenically to A/new jersey/8/76 (H1N1) and had a genome very similar to a contemporary enzootic swine influenza virus. The patient had had no known contact with swine, and the source of infection could not be determined. Only five possible secondary cases could be detected by retrospective investigation of 62 contacts, and there was no evidence of spread to the general community. swine influenza viruses circulate among pigs in the united states annually, and it is likely that sporadic transmissions to humans will continue to be detected. Nevertheless, person-to-person spread under these circumstances appears to be limited.- - - - - - - - - - ranking = 0.85714285714286keywords = swine (Clic here for more details about this article) |