1/6. osteoblastoma in lumbar vertebral body.We report a young man with low back pain suspected to have a disc protrusion. Imaging suggested a tumour of the dorsal portion of the fifth lumbar vertebral body. Operation suggested a giant-cell tumour and subsequent histology showed an osteoblastoma. All typical imaging features of osteoblastoma are demonstrated in this rather uncommon location. Contrast-enhancing bone-marrow oedema on MRI, with mild enhancement of the tumour, together with the CT appearances were the clues to the diagnosis.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/6. osteoblastoma of the patella: case report.A 34-year-old man came to our clinic because of left knee pain and mild swelling. Local tenderness over the peripatellar area was observed during physical examination. The range of motion of the knee was full. The radiographic presentation of the patella revealed an osteolytic lesion with a thin sclerotic rim without evidence of extra-articular involvement. The computed tomography revealed an upper pole intraosseous lesion. Intralesional curettage and allogeneic bone grafting were carried out. The pathologic examination demonstrated primitive osteoblasts, with osteoid features and many giant cells. A diagnosis of the osteoblastoma was made. Following surgery, the patient regained full range of motion and was pain-free. Complete healing of the lesion without evidence of recurrence was noted in follow-up radiographs 2 years postoperatively.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
3/6. An unusual presentation of giant cell tumour (osteoclastoma).The number of well-documented true giant cell tumours arising in any of the craniofacial bones is small, but they do exist. A 19 year old female, Ms. KS, presented with complain of progressive enlargement of facial bones especially jaw bones, then orbit symmetrically since the age of 7. There was bilateral gross enlargement of mandible, maxilla, orbital walls, causing displacement of eye medially and upwards. The visual acuity of both eyes were 6/36 and 6/18 with best correction. Extra ocular movements were restricted because of bony growth and conjunctiva over inferior fornix were keratinized due to exposure. Fine needle aspiration (FNAC) from the side of bony growth showed plenty of osteoclasts with multinucleated giant cells. The level of serum alkaline phosphatase were highly increased. She underwent orbitotomy and a part of tissue was sent for biopsy which revealed multiples of mononucleargiant cells and tumour cells.- - - - - - - - - - ranking = 7keywords = giant (Clic here for more details about this article) |
4/6. Fine needle aspiration diagnosis of aggressive giant cell tumor of bone. A case report.giant cell tumors of bone are neoplasms with potential local and systemic aggressiveness. A case of giant cell tumor with radiologic and histologic features suggestive of locally aggressive behavior is reported. Cytologic material was obtained by fine needle aspiration from an intraosseous tumor that destroyed the cortex and from the invaded, adjacent soft tissues. The smears from the osseous aspirate showed the typical cytologic features of giant cell tumor, whereas the invaded tissues had a prominent loss of cohesiveness between mononucleate and giant cells. In addition, mitotic figures in the mononucleate component were noticeable. The differential diagnosis based on clinical and cytologic findings is discussed.- - - - - - - - - - ranking = 7keywords = giant (Clic here for more details about this article) |
5/6. Partial ablation of benign osteoblastoma: a case report.osteoblastoma is a rare bone tumor involving spine, long bones and infrequently skull, especially with sinus localization. The orbital localization of the neoplasia may cause axial or paraxial exophthalmus, vertical diplopia, pulsatile orbital pain, soft tissue swelling with skin erythema. In addition the osteoblastoma may cause an optic nerve compression, with optic disc edema up to optic nerve atrophy. We describe a case of giant benign osteoblastoma with frontal occurrence and orbital involvement with optic nerve compression. Surgery was performed in order to obtain the partial ablation of the neoplasia. After a 4-year follow-up there was no evidence of recurrence.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
6/6. Giant osteoblastoma of temporal bone. Case report.Benign osteoblastoma is an uncommon bone tumor accounting for approximately 1% of all bone tumors. There are only 35 cases of skull osteoblastoma reported in the literature. We describe the case of a 23 year old male with a giant osteoblastoma of temporal bone submitted to a total removal of the tumor after an effective embolization of all external carotid branches. The authors discuss diagnostic and management aspects of this uncommon skull tumor.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |