Cases reported "Osteochondroma"

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1/3. Radiation-induced osteochondroma of the T4 vertebra causing spinal cord compression.

    A case of a radiation-induced osteochondroma arising from the vertebral body of T4 in an 18-year-old man is reported. The patient presented with a history of progressive left lower extremity weakness. At 7 years of age, he had undergone resection of a cerebellar medulloblastoma and received adjunctive craniospinal irradiation and systemic chemotherapy. Both CT and MR imaging revealed an extradural mass contiguous with the posteroinferior endplate of the T4 vertebral body. This case indicates that radiation-induced osteochondroma should be considered in the differential diagnosis of patients with symptoms of myelopathy or nerve root compression and a history of radiation therapy involving the spine in childhood.
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2/3. Radiation-induced osteochondroma in the lumbar spine.

    A case of a radiation-induced osteochondroma occurring in the posterior elements of the L3 vertebra in a 29-year-old woman is reported. At age 16 months, the patient was treated for an abdominal neuroblastoma. There were also radiation changes affecting the spine, ribs, and ilium. The lesion was excised "en bloc" and a spinal fusion performed. This is the third reported case of such a lesion occurring in the lumbar spine consequent to radiation therapy. The extremely long, latent period between radiation treatment and diagnosis of secondary tumor should be noted.
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3/3. Malignant degeneration of radiation-induced osteochondroma.

    A case of low-grade chondrosarcoma of the pelvis arising from a previous post-radiation osteochondroma is reported.
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