1/9. Tuberculous otitis media in a four-month-old infant.tuberculosis of the middle ear is currently a rare disease but still occurs and may cause permanent hearing loss. A four-month-old infant with chronic left-ear drainage was diagnosed with tuberculous otitis media by biopsy examination and PPD positivity without BCG. He was treated successfully with antituberculous therapy. tuberculosis should be considered in the differential diagnosis of chronic ear infection, especially in young infants.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/9. otitis media as a sign of Wegener's granulomatosis in childhood.Wegener's granulomatosis (WG) is a rare disease among paediatric patients. Chronic otitis media with or without facial nerve dysfunction is a known manifestation of the disease among adults. A case of a 15-year-old boy with WG, whose initial symptoms were acute otitis media and facial nerve paralysis, is presented. The otorhinolaryngological manifestations, as well as diagnostic and current treatment modalities in paediatric patients with WG, are discussed.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
3/9. Tuberculous otitis media: a difficult diagnosis and report of four cases.Tuberculous otitis media is a rare disease. Due to the condition's rarity and its usually indolent course, the diagnosis is often delayed. This can lead to irreversible complications, such as permanent hearing loss or facial nerve paralysis. tuberculosis of the middle ear cleft, as this disease's first presentation, is indeed very rare. Surgery may be carried out prior to diagnosis occasionally, i.e., middle ear exploration for chronic middle ear disease. We present four cases of tuberculous otitis media which occurred as the first presentation of the disease. The patients did not present with the classic symptoms of middle ear tuberculosis. The diagnosis was based on the histology following middle ear exploration for chronic middle ear disease. None of the patients presented any other systemic involvement. We present a review of this disease's clinical symptoms and the diagnostic tests available.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
4/9. Blastomycotic cranial osteomyelitis.This is the second case report of a temporal bone osteomyelitis caused by blastomyces dermatitidis, which presented as a chronic serous otitis media. The presenting serous otitis media was refractory to conventional medical and surgical management and progressed to a temporal bone osteomyelitis prior to diagnosis. B. dermatitidis is a rare fungal pathogen that causes a systemic pyogranulomatous disease that primarily manifests itself in the skin, bones, pulmonary, and genitourinary systems. If left untreated it is associated with a high rate of mortality. The otologic presentation of this rare disease is emphasized, while the clinical and therapeutic features are reviewed.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
5/9. Middle and posterior fossa aspergilloma.BACKGROUND: Aspergilloma of the brain is a rare disease. Among its varied presentations, a solitary intracranial mass is very uncommon. A preoperative diagnosis of it is very difficult, but a perioperative squash smear/frozen section can identify the pathology. Because of its rarity in immunocompetent patients and the difficulty in preoperative diagnosis, we have illustrated this case and its presentation and management. methods: A 27-year-old man presented with an h/o right-sided weakness along with headache and ear discharge. A computed tomographic (CT) scan showed a large irregular, space-occupying lesion in the middle and posterior cranial fossa. He had a mastoidectomy done 3 years before for chronic suppurative otitis media. After a symptom-free interval of 1 year, he was investigated for severe earache on the same side. A CT scan at that time showed a space occupying mass in the right temporal bone and right inferior temporal lobe. A biopsy and histopathology of the lesion revealed a chronic granulomatous mass. He was started on antituberculous drugs and was on it for 7 months at the time of presentation. RESULTS: He underwent a suboccipital craniectomy and total excision of the mass. Postoperatively, his consciousness improved but began to deteriorate on the third postoperative day. A repeat CT scan showed hydrocephalus and total removal of the mass. An external ventricular drain was put and he was ventilated, but he died on the fourth postoperative day. Histopathology report came as aspergilloma. CONCLUSION: This report highlights the rare presentation of aspergilloma in an immunocompetent patient. It emphasizes the importance of suspecting this disease in such patients and the role of intraoperative squash smear preparations or frozen section in the diagnosis as routine diagnostic procedures that will help in early pharmacotherapeutic interventions in adjunct to surgery.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
6/9. tuberculosis of the middle ear in an infant.tuberculosis of the middle ear is currently a rare disease. As most physicians are unfamiliar with the typical presenting features, the diagnosis is made too late, with resulting complications, such as irreversible hearing loss and facial nerve paralysis. A case report and review of the literature are presented, emphasizing that tuberculosis should be considered in the differential diagnosis of chronic ear infection.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
7/9. tuberculosis of the middle ear: review of the literature with an instructive case report.tuberculosis of the middle ear is currently a rare disease in developed countries but one that still occurs and typically causes significant morbidity manifested by profound and permanent hearing loss. diagnosis is difficult since most physicians are unfamiliar with the typical presenting features; in addition, special cultural and pathologic studies are required for diagnosis. A case report and review of the literature are presented to delineate typical clinical, epidemiologic, and laboratory features of tuberculous otitis media and associated tuberculous disease. A diagnostic and therapeutic plan is outlined that would allow early therapy and preservation of hearing.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
8/9. Cerebral aspergillosis in immunologically competent patients.aspergillosis of the central nervous system is a rare disease, especially if the patient's immune system is not compromised. The authors report three cases of cerebral aspergillosis in the immunocompetent state: a rhinocerebral form in a diabetic patient, a direct extension from chronic aspergillus otitis media, and a postoperative aspergillus brain abscess after brain tumor surgery. In spite of the poor prognosis of cerebral aspergillosis, two of the patients survived. The pathogenesis, predisposing factors, radiologic findings including magnetic resonance image, and the outcome are presented. The pertinent literature of cerebral aspergillosis is also reviewed.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
9/9. Tuberculous otitis media--a case report.tuberculosis of the middle ear is a rare disease. Due to a change in the typical clinical signs in recent years and the fact that the index of suspicion is low, there is frequently a considerable delay prior to diagnosis. This can lead to irreversible complications. A case of tuberculous otitis media is reported, re-emphasising the fact that this entity must be considered in the differential diagnosis of persistent suppurative otitis media.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |