1/121. Palatal lymphoepitheliomas and a review of head and neck lymphoepitheliomas.AIM: Lymphoepithelioma is principally a tumour of the nasopharynx with only sporadic cases arising elsewhere in the head and neck. We describe the clinical and imaging features of a group of rare lymphoepitheliomas related to the palate. patients AND methods: Four patients with lymphoepithelioma of the palate are described. In each case we retrospectively reviewed the clinical records, laboratory results, and imaging which consisted of computed tomography (CT) and ultrasound in all four cases and magnetic resonance imaging (MRI) in two patients. RESULTS: All four patients were ethnic Chinese (non-smokers, non-drinkers). All cases were Epstein-Barr virus (EBV) related. Tumour was related to the palate in two cases and extended into the nasal cavity in one patient. The fourth patient had a tumour in the floor of the nasal cavity with invasion of the palate on biopsy but not imaging. Cervical lymphadenopathy was seen in two cases, and the nasopharynx was normal in all the four patients. CONCLUSION: Lymphoepitheliomas occur in the region of the palate, where they are also EBV related in southern Chinese. Compared with the keratinizing squamous cell carcinomas, patients with lymphoepitheliomas have a better prognosis and these tumours are not tobacco or alcohol related. They should not be misdiagnosed as metastatic nasopharyngeal carcinoma (NPC), particularly since the nasopharynx is invariably normal on imaging and adequate nasopharyngeal biopsy is negative for malignancy.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
2/121. Acinic cell carcinoma of the palate: case report and immunohistochemical observation.We report a rare case of acinic cell carcinoma of the palate in a 63-year-old Japanese woman. Clinical examination demonstrated a firm, mobile mass without regional lymph-adenopathy. Histopathologically, the tumor was composed of large, polyhedral or round cells with basophilic granular cytoplasm (serous acinar-like cells) and reticular or clear cytoplasmic cells. These tumor cells were positive for the periodic acid-schiff reaction, but negative for alcian blue. The tumor nests were separated by thin vascular tissue and incompletely encapsulated. Immunohistochemically, the tumor cells exhibited positive reactivity for alpha-amylase, lactoferrin, secretory component, S100 protein, and epithelial membrane antigen, but were negative for actin, glial fibrillary acidic protein, keratin, and carcinoembryonic antigen. These results suggest that this tumor is well differentiated into serous acinar cells and that the reticular and clear cytoplasmic cells are a modified form of these cells.- - - - - - - - - - ranking = 2.5keywords = carcinoma (Clic here for more details about this article) |
3/121. dental caries after radiotherapy of the oral regions.Five cases of dental caries after radiation therapy of the oral regions for treatment of carcinomas are presented. The differences in clinical appearance and behavior between radiation caries and ordinary smooth-surface dental caries are described. The role of salivary gland irradiation and the resultant xerostomia in the development of these lesions is discussed. Some explanations are offered as to how these lesions develop in the light of current knowledge concerning plaque and the development of dental caries. Several measures that may be taken to reduce the incidence and severity of these lesions are suggested.- - - - - - - - - - ranking = 0.5keywords = carcinoma (Clic here for more details about this article) |
4/121. Management of a mucoepidermoid carcinoma of the palate. Report of a case.A case of mucoepidermoid carcinoma of the palate is presented, with emphasis on surgical treatment and postoperative care. It is thought that many oronasal communications may be prevented by the use of palatal splints relined with appropriate soft-tissue conditioners at frequent intervals.- - - - - - - - - - ranking = 2.5keywords = carcinoma (Clic here for more details about this article) |
5/121. Intraoral papillary cystadenoma lymphomatosum.The literature related to intraoral papillary cystadenoma lymphomatosum is critically reviewed and the reported cases analyzed to determine the average age, sex, and race of patients, and the site distribution of this curious lesion. Two new cases are reported. The histogenesis and differential diagnosis from cystadenocarcinoma are briefly discussed.- - - - - - - - - - ranking = 0.5keywords = carcinoma (Clic here for more details about this article) |
6/121. Necrotizing sialometaplasia.Three cases of necrotizing sialometaplasia of minor salivary glands are presented. Clinically and pathologically, this nonneoplastic lesion of the palate can be easily mistaken for carcinoma. The main histologic features are localized infarction of minor salivary glands and extensive squamous metaplasia with retention of the lobular architecture of the involved glands. The possible etiologic factors are discussed.- - - - - - - - - - ranking = 0.5keywords = carcinoma (Clic here for more details about this article) |
7/121. Primary malignant melanoma of the hard palate.A case of malignant melanoma of the oral cavity is presented. The very high frequency of squamous cell carcinoma of the palate in Visakhapatnam, india, is compared to the rarity of malignant melanoma, even though pigmentation of the oral cavity is quite common in this geographical region.- - - - - - - - - - ranking = 0.5keywords = carcinoma (Clic here for more details about this article) |
8/121. Basal cell adenocarcinoma of the palate with squamous metaplasia.Basal cell adenocarcinoma is a rare salivary gland tumour, especially in minor glands. The clinical, histological, and immunohistochemical features of a case involving the palate are described. Formalin fixed, paraffin embedded sections of the tumour were examined in haematoxylin and eosin (H&E) sections and also using immunostaining for cytokeratins 7, 8, 13, 14, 18, 19, vimentin, muscle specific actin (HHF35), and laminin. H&E sections showed that the tumour was composed mainly of basaloid cells and a striking feature was the presence of squamous metaplasia. Neural invasion was also conspicuous. Immunohistochemical reactions indicated that cytokeratin 14 was expressed by all tumour cells and vimentin by all cells except those in the areas of squamous metaplasia. The remaining cytokeratins and actin were present in some of the tumour cells, while laminin showed discreet positivity around cell arrangements. The foci of squamous metaplasia and the immunohistochemical findings are helpful in distinguishing basal cell adenocarcinoma from other salivary gland tumours which show basaloid cells.- - - - - - - - - - ranking = 3keywords = carcinoma (Clic here for more details about this article) |
9/121. Polymorphous low-grade adenocarcinoma of the oral cavity.Polymorphous low-grade adenocarcinoma (PLGA) is a neoplasm arising most commonly within the minor salivary glands of the oral cavity. Not recognized as a distinct entity until 1983, PLGA was often misdiagnosed as adenoid cystic carcinoma or pleomorphic adenoma. PLGA is thought to be the second most common salivary gland tumor after mucoepidermoid carcinoma. Affecting individuals later in life, PLGA often presents as a firm, painless nodule that exhibits a locally aggressive, infiltrative pattern. Because of PLGA's slow growth rate and low rate of metastasis, differentiation from other disease entities is crucial for treatment modalities. The study presented here reviews three cases of PLGA, their treatment and follow-up.- - - - - - - - - - ranking = 3.5keywords = carcinoma (Clic here for more details about this article) |
10/121. Mucoepidermoid carcinoma of the palate in a child.Salivary gland tumors are rare in children but when they involve the minor salivary glands, there is an increased risk that they will be malignant. The clinical and histopathologic features of a palatal mucoepidermoid carcinoma in an 8 year-old boy are presented. Differentiating this entity from common reactive and benign neoplastic lesions is discussed in order to prevent a delay in diagnosis and the potential for mismanagement.- - - - - - - - - - ranking = 2.5keywords = carcinoma (Clic here for more details about this article) |
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