1/15. Juvenile hyaline fibromatosis complicated with oral squamous cell carcinoma: a case report.A 45-year-old woman was referred because of swelling of the palate, gingival hypertrophy, and multiple cutaneous tumors. She had many cutaneous tumors, which covered most of her body, and she also displayed contractures of the major joints. Maxillary and mandibular gingival hypertrophy, malposition of the teeth, and swelling of the hard palate were the oral findings. The histopathologic features of the cutaneous and gingival tumors were consistent with hyaline fibromatosis, and the swelling of the palate proved to be a squamous cell carcinoma. The carcinoma was treated with tegafur/uracil and seemed to respond to this therapy.- - - - - - - - - - ranking = 1keywords = gingiva (Clic here for more details about this article) |
2/15. Oral mucosal melanoma: a series of case reports.INTRODUCTION: Due to the rarity of oral malignant melanomas case reports are a necessary source of information. Ten new cases are reported with a minimum follow-up of 3 years. patients AND methods: patients were treated during a period of 10 years. Clinical, demographic and pathologic findings were examined. RESULTS: In 6 males (60%) and 4 females with a mean age of 64.3 years the tumour locations were: hard palate-maxillary gingiva (3 cases), maxillary gingiva (2), lower gingiva (2), tongue (2), hard/soft palate-buccal mucosa (1). Pre-existing melanotic pigmentation had been present in 4 patients. Four patients were in stage I, 5 in stage II, and 1 in stage III. Surgical excision was the primary treatment in 9 cases. Five patients underwent simultaneous neck dissections. All patients received radiation and multimode adjuvant therapies. After a 3-year follow-up 3 patients are still alive (50% (2/4) of those presenting in stage I and 20% (1/5) in stage II). CONCLUSIONS: Due to the rarity of oral melanoma, individual experience is limited. The poor prognosis and the different treatments reflect this situation.- - - - - - - - - - ranking = 1keywords = gingiva (Clic here for more details about this article) |
3/15. Malignant melanoma of the oral cavity--case reports and review of literature.melanoma is a malignant tumor of melanocytes or their precursor cells. It is the third most common skin cancer and is one of the most biologically unpredictable neoplasms. sunlight is an important etiological factor in cutaneous melanoma. Oral melanoma is relatively uncommon, exhibiting a definite predilection for palate and maxillary gingiva, and is twice as common in males as in females. We herewith report three cases of oral melanoma out of which two occurred on the palate and one in the maxillary gingiva. Their clinical presentations, histopathology and management are discussed.- - - - - - - - - - ranking = 0.66666666666667keywords = gingiva (Clic here for more details about this article) |
4/15. Myeloid sarcoma of the maxillary bone.Myeloid sarcoma (MS) is a malignant tumour of myeloblasts rarely occurring in the maxillary bone. The tumour may precede or be concurrent with leukaemic infiltration of the bone marrow or herald blastic transformation of a myelodysplastic syndrome or a chronic myeloproliferative disorder. Myeloid sarcoma is uncommon in the oral cavity, but it can involve the palate, gingiva, extraction socket, and cheek. Recognition and diagnosis of myeloid sarcoma involving the soft tissues of the oral cavity in an otherwise asymptomatic patient is important and mandates an appropriate haematological diagnostic workup. We herein report on a new case without any evidence of haematological disorders. We discuss the pathological diagnosis and the therapeutical approaches.- - - - - - - - - - ranking = 0.33333333333333keywords = gingiva (Clic here for more details about this article) |
5/15. Extensive papillomatosis of the palate exhibiting epithelial dysplasia and HPV 16 gene expression in a renal transplant recipient.We report a unique case of extensive papillomatosis of the palate in a renal transplant recipient. The condition resembled inflammatory papillary hyperplasia; it exhibited severe epithelial dysplasia and concurred with generalized gingival hyperplasia. We document and discuss the probable multifactorial etiology of the lesions, including evidence for human papillomavirus (HPV) type 16 expression, as detected by in situ reverse transcription polymerase chain reaction. This report illustrates the need for careful clinical investigation and follow-up of immunosuppressed individuals presenting with apparently benign, common oral lesions.- - - - - - - - - - ranking = 0.33333333333333keywords = gingiva (Clic here for more details about this article) |
6/15. Malignant schwannoma and melanoma occurring in the maxilla.A rare case of malignant melanoma of the hard palate following malignant schwannoma of the left maxilla in a 47-year-old woman is reported. Twenty-two months after surgical excision of malignant schwannoma with postoperative radiation and chemotherapy, malignant melanoma appeared with symptoms of gingival bleeding and swelling. Although the patient was treated by the partial maxillectomy with radical neck dissection and postoperative chemotherapy and adjuvant immunotherapy, she died of multiple distant metastases 9 months after the oral manifestation. A possible histological relationship of both tumors which are considered to be derived from the neural crest cells is also discussed.- - - - - - - - - - ranking = 0.33333333333333keywords = gingiva (Clic here for more details about this article) |
7/15. Kinky hair disease. Report of a case.A confirmed case of kinky hair disease is described. Findings include a defect in copper metabolism, peculiar facies, retrognathia, skeletal open-bite, generalized gingival enlargement, and skeletal radiographic abnormalities.- - - - - - - - - - ranking = 0.33333333333333keywords = gingiva (Clic here for more details about this article) |
8/15. Primary malignant melanoma of the mouth.This report described primary malignant melanoma of the maxilla in the region of the palate and gingiva, the two most common locations of oral melanoma. It fulfilled the three criteria for a primary lesion as described by Greene and others, that is, malignant melanoma was demonstrated in the oral mucosa by biopsy examination, intraepidermal activity was present, and melanoma was not present at any other site. Treatment consisted of partial maxillectomy and the immediate use of maxillofacial prosthetics to offer the patient the maximum comfort in early rehabilitation.- - - - - - - - - - ranking = 0.33333333333333keywords = gingiva (Clic here for more details about this article) |
9/15. Acquired dyskeratotic leukoplakia.A 36-year-old woman developed progressive dyskeratotic leukoplakia of the palate, lips, attached gingiva, and labial surfaces of the genitalia. On microscopic examination, clusters of dyskeratotic cells were found throughout the epithelium, except in the basal cell layer. The clinical and histologic differential diagnosis included candidiasis, oral hairy leukoplakia, lichen planus, condyloma acuminatum, Darier's disease, hereditary benign intraepithelial dyskeratosis, and white sponge nevus. Her clinical and histologic findings do not permit classification into any of these well-recognized entities.- - - - - - - - - - ranking = 0.33333333333333keywords = gingiva (Clic here for more details about this article) |
10/15. Progressive changes of Kaposi's sarcoma of the gingiva and palate. Case report in an AIDS patient.As the incidence of acquired immunodeficiency syndrome (AIDS) cases is rapidly increasing, it is expected that the oral lesions of Kaposi's sarcoma (KS) related to AIDS will be encountered more frequently. The progressive changes of KS of the gingiva and palate are described in an AIDS patient who has been monitored for 7 months. In the initial stage, the oral manifestations of KS can be confused with various other lesions. The histopathological appearance includes proliferating slit-like vascular channels and scattered macrophages containing numerous hyaline, eosinophilic granules. Rapid neoplastic proliferation seems to be related to cyclical episodes of impaired immunity.- - - - - - - - - - ranking = 1.6666666666667keywords = gingiva (Clic here for more details about this article) |
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