Cases reported "Palatal Neoplasms"

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1/281. Extranodal follicular dendritic cell sarcoma of the palate.

    Follicular dendritic cell tumors are uncommon and usually occur in lymph nodes. We report the case of a follicular dendritic cell tumor that occurred in the palate of a 14-year-old boy and manifested itself as a nodular mass. Histologically, the neoplasm consisted of spindle-shaped or oval-shaped cells with eosinophilic cytoplasms and nuclei with delicate, dispersed chromatin. The lesional cells were principally arranged in diffuse, fascicular patterns with vaguely whorled or storiform areas. Focal multinucleate tumor giant cells and lymphocytes were observed throughout the neoplasm. Immunohistochemically, tumor cells were positive for the follicular dendritic cell markers CD21, CD35, and CD23 and for S-100 protein, CD68, and muscle-specific actin. Tumor cells were negative for LCA, CD20, EMA, CK (AE1/AE3), HMB45, and CD34. lymphocytes were positive for LCA and CD45RO. Although follicular dendritic cell sarcoma is a very uncommon tumor, it should be included in the differential diagnosis of tumors in this location.
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2/281. Mixed-type liposarcoma of the oral cavity: a case with unusual features and a long survival.

    A case of mixed-type liposarcoma, which showed unusual dedifferentiation in the recurrence, is reported. The rapidly growing mass in the palate of a 60-year-old Japanese woman first revealed a combination of myxoid liposarcoma with features resembling storiform malignant fibrous histiocytoma. The recurrent neoplasm, showing an abrupt transition between myxoid and non-lipogenic parts, partially reverted to sclerosing well-differentiated liposarcoma. The patient died 10.1 years after the first operation.
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3/281. Antenatal sonographic diagnosis of epignathus at 15 weeks of pregnancy.

    Epignathus is a rare, benign, congenital teratoma of the hard palate. Most of these teratomas are unidirectional and protrude through the mouth. Hence, the prognosis depends on the size of the tumor and the degree of face distortion and airway obstruction that it causes. However, some epignathi protrude bidirectionally, involving and destroying the brain tissue, resulting in a poor prognosis. This report presents a case of ultrasonographic detection of a bidirectional epignathus at 15 weeks of pregnancy.
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4/281. Palatal lymphoepitheliomas and a review of head and neck lymphoepitheliomas.

    AIM: Lymphoepithelioma is principally a tumour of the nasopharynx with only sporadic cases arising elsewhere in the head and neck. We describe the clinical and imaging features of a group of rare lymphoepitheliomas related to the palate. patients AND methods: Four patients with lymphoepithelioma of the palate are described. In each case we retrospectively reviewed the clinical records, laboratory results, and imaging which consisted of computed tomography (CT) and ultrasound in all four cases and magnetic resonance imaging (MRI) in two patients. RESULTS: All four patients were ethnic Chinese (non-smokers, non-drinkers). All cases were Epstein-Barr virus (EBV) related. Tumour was related to the palate in two cases and extended into the nasal cavity in one patient. The fourth patient had a tumour in the floor of the nasal cavity with invasion of the palate on biopsy but not imaging. Cervical lymphadenopathy was seen in two cases, and the nasopharynx was normal in all the four patients. CONCLUSION: Lymphoepitheliomas occur in the region of the palate, where they are also EBV related in southern Chinese. Compared with the keratinizing squamous cell carcinomas, patients with lymphoepitheliomas have a better prognosis and these tumours are not tobacco or alcohol related. They should not be misdiagnosed as metastatic nasopharyngeal carcinoma (NPC), particularly since the nasopharynx is invariably normal on imaging and adequate nasopharyngeal biopsy is negative for malignancy.
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5/281. Sialadenoma papilliferum of the palate: case report and literature review.

    Sialadenoma papilliferum (SP) is a rare tumor of salivary gland ducts which bears a strong histologic resemblance to the more common syringocystadenoma papilliferum (SCAP). We report a case occurring on the palate of a 50-year-old man, and review the clinical and histologic features of this tumor. Because of the histologic similarities between these two tumors and squamous papillomas, polymerase chain reaction (PCR) for human papilloma virus (HPV) dna was performed on this tumor and on two cases of SCAP, with negative results. To our knowledge, this is the first case report of SP in the dermatopathology literature.
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6/281. Acinic cell carcinoma of the palate: case report and immunohistochemical observation.

    We report a rare case of acinic cell carcinoma of the palate in a 63-year-old Japanese woman. Clinical examination demonstrated a firm, mobile mass without regional lymph-adenopathy. Histopathologically, the tumor was composed of large, polyhedral or round cells with basophilic granular cytoplasm (serous acinar-like cells) and reticular or clear cytoplasmic cells. These tumor cells were positive for the periodic acid-schiff reaction, but negative for alcian blue. The tumor nests were separated by thin vascular tissue and incompletely encapsulated. Immunohistochemically, the tumor cells exhibited positive reactivity for alpha-amylase, lactoferrin, secretory component, S100 protein, and epithelial membrane antigen, but were negative for actin, glial fibrillary acidic protein, keratin, and carcinoembryonic antigen. These results suggest that this tumor is well differentiated into serous acinar cells and that the reticular and clear cytoplasmic cells are a modified form of these cells.
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7/281. Management of a mucoepidermoid carcinoma of the palate. Report of a case.

    A case of mucoepidermoid carcinoma of the palate is presented, with emphasis on surgical treatment and postoperative care. It is thought that many oronasal communications may be prevented by the use of palatal splints relined with appropriate soft-tissue conditioners at frequent intervals.
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8/281. Necrotizing sialometaplasia.

    Three cases of necrotizing sialometaplasia of minor salivary glands are presented. Clinically and pathologically, this nonneoplastic lesion of the palate can be easily mistaken for carcinoma. The main histologic features are localized infarction of minor salivary glands and extensive squamous metaplasia with retention of the lobular architecture of the involved glands. The possible etiologic factors are discussed.
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9/281. Blue nevus of the hard palate.

    The occurrence of a blue nevus of the hard palate in a 72-year-old man is reported. Of the 25 previously documented cases of blue nevus of the oral cavity, 19 were on the hard palate, three on the upper lip, and one each on the lower lip, buccal mucosa, and soft palate. Fourteen were in women and 11 were in men. All but five patients were younger than 50 years of age. The size of the asymptomatic, flat to somewhat elevated, blue-black lesion varied up to 5 mm except for one that was 10 mm in the greatest dimension. Most nevi were of unknown duration and were found incidentally during dental examination. The histogenesis of extracutaneous blue nevus is undetermined but derivation from melanogenic potential of Schwann or endoneurial cells or from stimulation of retained melanoblasts in the stroma developing into melanocytes and formation of blue nevus is possible.
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10/281. Primary malignant melanoma of the hard palate.

    A case of malignant melanoma of the oral cavity is presented. The very high frequency of squamous cell carcinoma of the palate in Visakhapatnam, india, is compared to the rarity of malignant melanoma, even though pigmentation of the oral cavity is quite common in this geographical region.
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