1/17. Central retinal vein occlusion due to herpes zoster as the initial presenting sign in a patient with acquired immunodeficiency syndrome (AIDS).Central retinal vein occlusion (CRVO) due to herpes zoster has rarely been reported. Varicella zoster virus is a common opportunistic infection in patients with AIDS. This case report is about a 40-year-old man with herpes zoster ophthalmicus and central retinal vein occlusion of the right eye who is hiv-positive. Although the lesion resolved following treatment with intravenous acyclovir and oral steroid, the patient subsequently developed florid disc neovascularization and vitreous hemorrhage. The paper highlights CRVO as the initial presentation in an AIDS patient with herpes zoster ophthalmicus.- - - - - - - - - - ranking = 1keywords = neovascularization (Clic here for more details about this article) |
2/17. Optic disc swelling in an adolescent with insulin dependent diabetes mellitus.A 14-year-old Ukrainian girl with uncontrolled insulin dependent diabetes developed bilateral optic disc swelling when diabetic treatment was instituted. There was no retinal ischaemia. The disc swelling resolved completely over 8 months without specific ocular therapy. Disc swelling in juvenile diabetics must be differentiated from disc neovascularization. These patients may develop retinal ischaemia and neovascularization after the disc changes resolve.- - - - - - - - - - ranking = 2keywords = neovascularization (Clic here for more details about this article) |
3/17. Occlusive retinal arteriolitis with neovascularization.A 34-year-old white woman who had used oral contraceptives for six years showed an occlusive bilateral retinal arteriolitis that resulted in a branch arteriolar occlusion in the right eye and retinal neovascularization. Three years later, we observed active arteriolitis in the left eye with successive occlusion of several branch arterioles. The disease has shown spontaneous remissions and exacerbations. An extensive medical evaluation revealed only old pulmonary granulomatous disease and an elevated sedimentation rate in association with exacerbations of the arteriolitis.- - - - - - - - - - ranking = 5keywords = neovascularization (Clic here for more details about this article) |
4/17. Infantile case of occlusive microvascular retinopathy after bone marrow transplantation.BACKGROUND: A variety of anterior and posterior segment ocular complications following bone marrow transplantation (BMT) have been well documented in adults and children, but retinal complications after BMT in infants have rarely been reported. CASE: A 6-month-old male infant developed occlusive microvascular retinopathy after BMT to treat acute lymphocytic leukemia. OBSERVATIONS: Four months after the transplantation, retinal edema, hemorrhage, soft exudates, and neovascularization were found in the posterior pole fundus of the right eye and in the peripheral fundus of the left eye. After oral prednisolone was administered, the retinal lesions regressed and cicatrices with chorioretinal atrophy and fibrous tissue formed. CONCLUSIONS: Neovascularization following occlusive microvascular retinopathy after BMT in infant eyes responds well to oral prednisolone. The visual prognosis depends on the foveal involvement of the retinopathy.- - - - - - - - - - ranking = 1keywords = neovascularization (Clic here for more details about this article) |
5/17. Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration.PURPOSE: To report the short-term safety, biologic effect, and a possible mechanism of action of intravitreal bevacizumab in patients with neovascular age-related macular degeneration (AMD). DESIGN: Interventional, consecutive, retrospective case series. PARTICIPANTS: Eighty-one eyes of 79 patients with subfoveal neovascular AMD. methods: patients received intravitreal bevacizumab (1.25 mg) on a monthly basis until macular edema, subretinal fluid (SRF), and/or pigment epithelial detachment (PED) resolved. Ophthalmic evaluations included nonstandardized Snellen visual acuity (VA), complete ophthalmic examination, fluorescein angiography, and optical coherence tomography (OCT). MAIN OUTCOME MEASURES: Assessments of safety, changes in Snellen VA, OCT retinal thickness, and angiographic lesion characteristics were performed. RESULTS: No significant ocular or systemic side effects were observed. Most patients (55%) had a reduction of >10% of baseline retinal thickness at 1 week after the injection. At 4 weeks after injection, 30 of 81 eyes demonstrated complete resolution of retinal edema, SRF, and PEDs. Of the 51 eyes with 8 weeks' follow-up, 25 had complete resolution of retinal thickening, SRF, and PEDs. At 1, 4, 8,and 12 weeks, the mean retinal thickness of the central 1 mm was decreased by 61, 92, 89, and 67 mum, respectively (P<0.0001 for 1, 4, and 8 weeks and P<0.01 for 12 weeks). At 4 and 8 weeks, mean VA improved from 20/200 to 20/125 (P<0.0001). Median vision improved from 20/200 to 20/80(-) at 4 weeks and from 20/200 to 20/80 at 8 weeks. CONCLUSIONS: Short-term results suggest that intravitreal bevacizumab (1.25 mg) is well tolerated and associated with improvement in VA, decreased retinal thickness by OCT, and reduction in angiographic leakage in most patients, the majority of whom had previous treatment with photodynamic therapy and/or pegaptanib. Further evaluation of intravitreal bevacizumab for the treatment of choroidal neovascularization is warranted.- - - - - - - - - - ranking = 1keywords = neovascularization (Clic here for more details about this article) |
6/17. Subretinal neovascularization in anterior ischemic optic neuropathy.A 66-year-old man with typical anterior ischemic optic neuropathy in one eye suffered from edema of the optic disc without functional changes in the fellow eye. However, 7 months later, a reduction in visual acuity, a change in the visual field and a worsening of the contrast-sensitivity curve demonstrated the development of typical anterior ischemic optic neuropathy in this eye as well. After another 6-month period, in addition to these changes, an extensive subretinal neovascular membrane developed in the papillomacular area, which further reduced the patient's visual acuity and required treatment with laser photocoagulation. To our knowledge, this is the first case report of the occurrence of a subretinal neovascular membrane as a complication of anterior ischemic optic neuropathy.- - - - - - - - - - ranking = 4keywords = neovascularization (Clic here for more details about this article) |
7/17. Peripapillary subretinal neovascularization in peripheral uveitis.A 29-year-old white female with peripheral uveitis developed bilateral disc edema and unilateral peripapillary subretinal neovascularization which was successfully treated with argon laser photocoagulation. To our knowledge, this is the first reported case of peripapillary subretinal neovascularization complicating the course of peripheral uveitis.- - - - - - - - - - ranking = 6keywords = neovascularization (Clic here for more details about this article) |
8/17. Acute anterior ischemic optic neuropathy in birdshot retinochoroidopathy.Visual loss in birdshot retinochoroidopathy has been reported to be produced by cystoid macular edema, optic atrophy, epiretinal macular membranes and subretinal neovascularization. We present a patient with this syndrome in whom the visual loss was due to an acute anterior ischemic optic neuropathy. The possible common pathogenesis of both diseases is discussed.- - - - - - - - - - ranking = 1keywords = neovascularization (Clic here for more details about this article) |
9/17. Subretinal neovascularization and papilledema associated with pseudotumor cerebri.A 31-year-old man, on routine ocular examination, was found to have bilateral papilledema. Neurologic evaluation confirmed elevated cerebrospinal pressure with no mass lesion and a diagnosis of pseudotumor cerebri was made. A tiny subretinal hemorrhage adjacent to the right optic disk was found to be secondary to subretinal neovascularization. Over the course of several months, the papilledema resolved. However, the neovascular membrane extended further toward the fovea and was subsequently obliterated with argon laser photocoagulation.- - - - - - - - - - ranking = 5keywords = neovascularization (Clic here for more details about this article) |
10/17. review of diseases of the optic nerve, optic tract, and visual cortex: 1975-76.The ophthalmic literature dealing with diseases of the optic nerve, the optic tracts, and the visual cortex was reviewed for the period November 1975 through November 1976. Twenty-nine papers on topics of interest to optometrists were abstracted. The main areas of interest include: papilledema and optic atrophy (with ophthalmoscopic signs of both optic atrophy and papilledema); giant-cell arteritis; papillitis; interesting malformations of the face, palate, and orbital position that occur in conjunction with microphthalmus, situs inversus, and hypoplasia and aplasia of the optic nerve; the proposed association of myopia with unusual eyebrows; myelinated nerve fibers at the nerve head; pigment anomalies; the continuing discussion of nerve-head blood supply; an unexpected cause for nerve-head neovascularization; the importance of the swinging-flashlight test in the diagnosis of glaucoma; an unusual type of glaucomatous cupping; doubts about the peripapillary "halo" as a sign of glaucoma; new uses for old field tests; and new methods of ocular photography.- - - - - - - - - - ranking = 1keywords = neovascularization (Clic here for more details about this article) |
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