1/24. Acrokeratosis paraneoplastica (Bazex syndrome) with adenocarcinoma of the colon: report of a case and review of the literature.Acrokeratosis paraneoplastica is a rare disease and is uncommon even in patients with upper aerodigestive tract cancer. We report a 63-year-old man with a 1-month history of numerous pruritic lesions and vesicles on both feet. Although he had received local therapy, progressive dense scale formation involving both palms and both soles was found. colonoscopy was performed because of hematochezia, and it revealed an early colon cancer. After the resection of the cancer, the skin lesions began to fall off dramatically. To the best of our knowledge, there is no report of acrokeratosis paraneoplastica associated with colon cancer in the literature. This is the first case report of acrokeratosis paraneoplastica associated with early colon cancer.- - - - - - - - - - ranking = 1keywords = acrokeratosis (Clic here for more details about this article) |
2/24. Paraneoplastic skin manifestations of lung cancer.Two cases are reported illustrating a parallel course of extensive skin manifestations and lung cancer. The cases presented features of paraneoplastic acrokeratosis (Bazex's syndrome) and erythema gyratum repens though they did not completely correspond to these well-defined conditions. In both cases the cutaneous eruption appeared more than a year prior to the diagnosis of lung cancer, and the skin disease resolved completely within half a year following surgical removal of the cancer. The need is stressed for repeated cancer screens when a cutaneous marker of internal malignancy is suspected.- - - - - - - - - - ranking = 0.5keywords = acrokeratosis (Clic here for more details about this article) |
3/24. Bazex syndrome.Bazex syndrome is a paraneoplastic acrokeratosis appearing mostly at the same time as the underlying neoplasm. We report a typical case with a squamous cell carcinoma of the tongue and classical cutaneous symptoms disappearing with the treatment of the tumour.- - - - - - - - - - ranking = 0.5keywords = acrokeratosis (Clic here for more details about this article) |
4/24. Bullous lesions in Bazex syndrome and successful treatment with oral psoralen phototherapy.A 59-year-old man presented with a psoriasiform dermatitis with associated bullae and destructive nail dystrophy of the hands and feet. He had lost 10 kg weight over 6 months and a mass in the neck was noted. He was provisionally diagnosed with Bazex syndrome (acrokeratosis paraneoplastica) and subsequent investigations revealed a squamous cell carcinoma in the right piriform fossa. His skin lesions were treated with oral psoralen and ultraviolet A phototherapy and this cleared the cutaneous changes, but the nail changes have persisted at 18 months follow up.- - - - - - - - - - ranking = 0.5keywords = acrokeratosis (Clic here for more details about this article) |
5/24. Acrokeratosis paraneoplastica of Bazex.Bazex disease is one of the rarer cutaneous paraneoplastic syndromes. It is characterized by psoriasiform changes on the digits, and in some patients spread to the ears, nose and in later stages to the limbs and trunk. The associated malignancy is typically a squamous cell carcinoma of the upper aerodigestive tract. We review the literature regarding acrokeratosis paraneoplastica of Bazex and report three cases which illustrate both the typical and some of the less common changes that are seen in the condition.- - - - - - - - - - ranking = 0.5keywords = acrokeratosis (Clic here for more details about this article) |
6/24. Flexural Bazex syndrome associated with tonsillar adenocarcinoma.Bazex Syndrome (acrokeratosis paraneoplastica) is characterized by a psoriasiform skin eruption that favors acral sites and has been associated with underlying malignancy in all reported cases. Squamous cell carcinoma of the upper third of the respiratory system and upper third of the gastrointestinal tract and squamous cell carcinoma of unknown primary with cervical lymph node metastasis are the most commonly associated neoplasms. Here we report a case of flexural Bazex syndrome with tonsillar adenocarcinoma.- - - - - - - - - - ranking = 0.5keywords = acrokeratosis (Clic here for more details about this article) |
7/24. Bazex syndrome (paraneoplastic acrokeratosis).Bazex syndrome (paraneoplastic acrokeratosis) is characterized by the presence of hyperkeratotic lesions on the nose, ears, palms, and soles that appear in association with malignancies of the upper aerodigestive tract, most often a squamous cell carcinoma. We present a case of Bazex syndrome and provide a review of the literature.- - - - - - - - - - ranking = 2.5keywords = acrokeratosis (Clic here for more details about this article) |
8/24. Acrokeratosis paraneoplastica: Bazex syndrome.Bazex syndrome is a paraneoplastic dermatosis characterized by acral psoriasiform lesions associated with an underlying neoplasm. We present the case of a 64-year-old patient that was diagnosed with squamous cell lung carcinoma after being evaluated for lesions compatible with paraneoplastic acrokeratosis. With a high frequency Bazex syndrome is the earliest marker of an underlying subclinical neoplasm. An early suspicion is of the outmost importance in order to perform a prompt diagnosis of an underlying malignancy. We propose a diagnostic algorithm upon suspicion of acrokeratosis paraneoplastica and review the pathogenesis of this entity.- - - - - - - - - - ranking = 1keywords = acrokeratosis (Clic here for more details about this article) |
9/24. Acrokeratosis paraneoplastica (Bazex syndrome): case report and review of literature.Acrokeratosis paraneoplastica of Bazex is a rare syndrome. This condition is a distinct skin marker of supra-diaphragmatic neoplasia. This syndrome is important because the cutaneous findings preceed the onset of symptoms referable to the underlying neoplasm by several months in majority of the cases. We report here a case of a 63-year-old cachectic female who had classic psoriasiform lesions of acrokeratosis of Bazex with underlying bronchogenic carcinoma of the right lung.- - - - - - - - - - ranking = 0.5keywords = acrokeratosis (Clic here for more details about this article) |
10/24. Cutaneous paraneoplastic syndrome (acrokeratosis paraneoplastica) preceding squamous cell carcinoma of the glottic larynx.paraneoplastic syndromes that occur in the minority of cancer patients are the produced signs and symptoms at distant sites from the tumour or its metastases. These syndromes may occur due to the production of substances by tumoural lesions that directly or indirectly cause distant symptoms or depletion of normal substances or host response to the tumours. A paraneoplastic syndrome may be the first sign of a malignancy so its recognition may be critical for early cancer detection. Most of the paraneoplastic syndromes associated with head and neck tumours are endocrinologic or neurologic; dermatologic syndromes are less common. head and neck cancers also have occasionally been reported in association with paraneoplastic syndromes and to date there are only a few cases in the literature about the presence of a cutaneous paraneoplastic syndrome as the first manifestation of a laryngeal cancer, especially glottic larynx cancer. A wide variety of cutaneous syndromes are associated with malignancies and these syndromes may precede, follow, or be concurrent with the underlying malignancy. In this report we present a case with cutaneous syndrome of acrokeratosis paraneoplastica preceding squamous cell carcinoma of glottic larynx, and review the other cutaneous paraneoplastic syndromes reported in the literature.- - - - - - - - - - ranking = 2.5keywords = acrokeratosis (Clic here for more details about this article) |
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