Cases reported "Periodontal Diseases"

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1/27. Burkitt-like lymphoma presenting as a periodontal disease in AIDS patients: a report of two cases.

    Burkitt-like lymphoma of the oral cavity is relatively uncommon in patients with acquired immunodeficiency syndrome (AIDS). The lesion usually appears as a solitary ulcerated mass with rapid onset. Some may present initially as gingival inflammation which delays final diagnosis and treatment. This report describes the presentations of multifocal intraoral Burkitt-like lymphoma in two Thai heterosexual men with AIDS. The clinical features and the radiographic findings in both cases mimicked a periodontal disease, showing extensive widening of the periodontal ligament space and loss of lamina dura in all segments of the molar teeth. The patients eventually died 5 and 14 months after they were diagnosed with hiv infection.
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ranking = 1
keywords = periodontal ligament, ligament
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2/27. Enamel matrix derivative for periodontal reconstructive surgery: technique and clinical and histologic case report.

    This paper describes a step-by-step technique for the application of Emdogain, a new enamel matrix derivative (EMD) graft material, for periodontal reconstructive surgery. A case report is presented with a 1-year follow-up. The rationale for use and advantages and disadvantages of EMD are discussed. An additional human histologic case report demonstrates that the formation of new bone, cementum, and periodontal ligament is possible following the use of EMD.
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ranking = 1
keywords = periodontal ligament, ligament
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3/27. The relationship between peripheral levels of leukocytes and neutrophils and periodontal disease status in a patient with congenital neutropenia.

    BACKGROUND: Congenital neutropenia is characterized by an almost total absence of neutrophils and increased susceptibility to infection. oral manifestations include ulcerations of mucous membranes, acute gingival inflammation with focal necrosis, and rapid loss of attachment. Treatment with recombinant human granulocyte colony-stimulating factor (rhG-CSF) increases neutrophil numbers and ameliorates the periodontal status. methods: We report the treatment of a 22-year-old male with congenital neutropenia (Kostman syndrome), referred to us due to periodontal disease, and the effect of treatment on peripheral neutropenia. diagnosis of neutropenia was made at year 1; at age 15, the patient started to receive injections of rhG-CSF, reducing the occurrence of infection and improving neutrophil count, although levels remained below normal. The patient underwent extraction of a molar at age 8; scaling, root planing, and modified Widman flaps at age 9; and oral hygiene maintenance every 2 to 3 months from age 18 to 21. At age 23, he initiated treatment at our periodontal clinic. The patient's gingiva was severely inflamed, and the dentition was covered with plaque and calculus. Attachment loss was advanced, all teeth were mobile, and bone loss was approximately 75% in most sites. Neutrophil counts were below normal, but other hematologic parameters were normal. Scaling and root planing were performed and the patient received antibiotics and chlorhexidine rinses twice each day for 2 weeks. Extracoronal splinting was performed, fluoride varnish was used to desensitize cervical areas, and tooth FDI #46 was restored. root planing and deplaquing were repeated, and the patient received subgingival chlorhexidine irrigation 13 times over one year. Assessments were made on presentation, after the initial treatment, and at 1 and 2 years post-treatment. RESULTS: Mean probing depth was reduced posttreatment with a further reduction during the maintenance period. This was correlated with an increase in attachment levels. Total white blood cells increased, due in part to an increase in neutrophils, reaching normal levels. CONCLUSIONS: This report demonstrates for the first time that periodontal therapy, resulting in decreased bacterial load, may result in restoration of normal levels of circulating neutrophils in individuals with congenital neutropenia under treatment with rhG-CSF. The results also suggest that periodontal pathogens may be associated with depressed neutrophil levels, even when patients receive treatment for neutropenia.
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ranking = 9.7805404222833E-5
keywords = membrane
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4/27. Defect morphology: effects on regenerative predictability and membrane selection.

    In clinical experience, guided tissue regeneration has been associated with complications, which include membrane exposure. The maintenance of a stable blood clot under the membrane is key to a successful regenerative outcome. This requires adequate membrane stabilization, tension-free suturing, and maintenance of a good vascular supply to the defect. Careful selection of defects after a thorough periodontal evaluation and modification of surgical techniques from those used for conventional resective procedures can lead to predictable outcomes for guided tissue regeneration.
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ranking = 0.00068463782955983
keywords = membrane
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5/27. Periodontal healing in humans using anorganic bovine bone and bovine peritoneum-derived collagen membrane: a clinical and histologic case report.

    The authors report the clinical and histologic data on the healing of a severe periodontal lesion obtained in a one-walled intrabony defect using anorganic bovine bone under a bovine peritoneum-derived collagen membrane. Eight months after surgery, a bone-like tissue replaced the lost tissues. A biopsy of this tissue was carried out. In the part of the specimen closer to the residual bony wall of the original defect, anorganic bone particles (ABP) appeared to be surrounded by a layer of newly formed bone; its osteocyte lacunae were colonized by osteocytes from the host, and actively secreting osteoblasts were observed in many microscopic fields. No resorption phenomena were observed in the ABP Newly formed cementum with actively secreting cementoblasts was present on the tooth surface, and well-oriented fibers inserting in both newly formed cementum and bone were observed. In an area far from residual bone, all ABP did not appear to be surrounded by newly formed bone. Osteocytic lacunae appeared not to be colonized by cells, and ABP was surrounded by dense connective tissue without osteoblasts near the grafted particles. A very limited amount of newly formed bone, without relations with ABP, was observed close to the root surface. From a clinical point of view, anorganic bone in association with a collagen membrane can be effective in the treatment of bony defects characterized by an unfavorable architecture. From a histologic point of view, the clinical appearance of bone regeneration is not always confirmed in the part of the defect far from the bony walls.
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ranking = 0.000586832425337
keywords = membrane
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6/27. Treatment of an osseous lesion associated with a severe palato-radicular groove: a case report.

    This is a case report that describes the management of a severe periodontal defect associated with a palato-radicular (palato-gingival) groove affecting the maxillary right lateral incisor of a 50 year-old male. The patient presented with pain, gingival swelling, and a 10 mm periodontal pocket on the distopalatal aspect of the right maxillary lateral incisor. The defect was initially treated by scaling and root planing. Several days later a flap was elevated, the osseous defect was debrided, and odontoplasty was performed to eliminate the groove. The root surface was treated with citric acid for 3 minutes, the osseous defect was filled with non-porous hydroxyapatite, a periodontal membrane was placed, and the flap was readapted to the tooth. postoperative care included systemic (minocycline) and local (chlorhexidine) antimicrobial therapy. The membrane was removed 6 weeks postoperatively and 14 months postoperatively the gingiva appeared healthy; radiographs suggested substantial resolution of the osseous defect and about 7 mm of probing attachment gain was recorded. Further studies are necessary to determine which of the several modes of therapy used to treat this lesion are necessary for success.
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ranking = 0.00019561080844567
keywords = membrane
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7/27. Healing of human suprabony lesions treated with guided tissue regeneration and coronally anchored flaps. case reports.

    Teflon membranes were interposed between soft tissue flaps and roots in 4 human suprabony lesions affecting the mandibular incisor teeth in 1 volunteer patient. 4 suprabony lesions affecting the mandibular incisor teeth were used as comparisons in a 2nd patient. All roots were debrided using ultrasonic and manual instruments and the most apical positioned calculus/site on the facial surface was notched. Flaps were sutured as coronally as possible using orthodontic brackets as anchors. Tissue blocks were removed 2 to 3 months after procedures and the facial aspects of all teeth were examined histologically. New attachment in the form of new "cementum with functionally oriented fibers" was seen within the calculus notch in 3 out of 4 membrane-treated sites and immediately apical to the notch at 1 site. The 4 comparison sites showed no evidence of new attachment within or adjacent to the notch. Rather, the gingival margins were located apical to the notch. Our observations suggest that guided tissue regeneration techniques improved coronal attachment responses in human suprabony lesions within the sample described.
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ranking = 0.00019561080844567
keywords = membrane
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8/27. guided tissue regeneration: observations from five treated cases.

    In this clinical investigation, a biodegradable collagen material was used in membrane and paste form to assess its suitability for use in guided tissue regeneration after surgery. A variety of healing responses in only the soft tissues were noted, ranging from gross necrosis to enhanced healing. The problems and limitations of regeneration procedures are discussed to explain the reasons for the observed healing of the tissues.
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ranking = 9.7805404222833E-5
keywords = membrane
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9/27. Oxidized cellulose mesh used as a biodegradable barrier membrane in the technique of guided tissue regeneration. A case report.

    In this case study oxidized cellulose mesh was shown to have potential for use as a biodegradable barrier membrane for regenerative procedures in furcation areas and interdental infrabony defects. The material was customized so as to protrude coronally to the soft tissue flaps and interdentally after surgery. The material resorbed and normal healing took place with crevicular depths less than 2 mm by 1 month postoperatively. By 6 months postoperatively, 2 of the sites showed crevice depths of 3 mm. Initially there was negligible recession, except in one site, but by 6 months after surgery some resistant to probing. It is, therefore, concluded that this material may have the potential for use as a biodegradable membrane in the technique of guided tissue regeneration.
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ranking = 0.000586832425337
keywords = membrane
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10/27. Human histologic responses to guided tissue regenerative techniques in intrabony lesions. case reports on 9 sites.

    9 sites of 8 teeth in 5 adults with severe periodontitis were treated by open surgical debridement followed by placement of 1 of 2 Teflon barrier membranes. Teeth were notched at both gingival margins and deepest visible calculus on the root. Barrier membranes were placed apical to alveolar crest and coronal to gingival notch. Flaps were sutured coronally and patients were placed on 1.2% chlorohexodine gluconate twice daily for 2 weeks, post-surgery. Subsequent to suture removal, patients returned for frequent plaque control until block removal. In order to observe early healing responses, 6 sites were harvested 5 to 8 weeks after surgical treatment. 3 additional sites were removed 14, 22 and 30 weeks respectively after surgical treatment. Histologically, new cementum was seen in a linear direction along root surfaces in 6 out of 9 sites (length of cementum = 0.5 to 1.7 mm). 3 sites showed no evidence of new attachment. At sites of cementogenesis, functionally-oriented fibers were inserted. The osseous seams opposite the new attachment often demonstrated osteogenesis. Regenerative responses were seen with both types of teflon membranes and were present as early as 5 weeks after surgery.
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ranking = 0.0002934162126685
keywords = membrane
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