1/31. Vasculitic neuropathy in a patient with inactive treated lepromatous leprosy.A 46 year old Asian male with previously treated lepromatous leprosy developed a stepwise multifocal sensory disturbance 25 years later. neurophysiology demonstrated marked deterioration from previous studies. sural nerve biopsy disclosed a vasculitic process superimposed on inactive lepromatous leprosy. Immunocytochemical stains for mycobacterial antigen showed deposits within nerve and vessel walls. A delayed vasculitic neuropathy precipitated by persisting mycobacterial antigen is proposed.- - - - - - - - - - ranking = 1keywords = leprosy, lepromatous (Clic here for more details about this article) |
2/31. Neural leprosy--a case report.Neural leprosy is rare. This is a report of a 63-year-old Indian man who had long standing multiple peripheral neuropathy. The slit skin smear for acid-fast bacilli of mycobacterium leprae was positive. The skin and nerve biopsies were normal. He was treated with rifampicin, dapsone and clofazimine.- - - - - - - - - - ranking = 0.68413529815842keywords = leprosy (Clic here for more details about this article) |
3/31. Three cases of pure neuritic (PN) leprosy at detection in which skin lesions became visible during their course.Pure neuritic leprosy (PN leprosy) is a type of leprosy with nerve involvement, but without obvious skin lesions. It is not uncommon in the south of bangladesh, but its nature is less recognized than that in other types of leprosy. male is dominant on its occurrence with higher disability grading. The histopathological study shows that the entire spectrum can be observed in nerves of PN leprosy. There was no relation among clinical parameters, such as the number and distribution of affected nerves, the immune response and its histopathology. Therefore the treatment of PN leprosy is not well-established at field level. Out of 1,741 newly detected cases by Dhanjuri leprosy Project--Khulna Branch (PIME Sisters) in Khulna, the south of bangladesh from 1994 to 1998, 141, or 8.10% were diagnosed as PN leprosy. 6 cases out of 1,741, or 0.34% were canceled afterwards because of wrong diagnosis, of which one misdiagnosed as PN leprosy. Three cases out of 140 of primary neuritic leprosy proved to have obvious skin lesions some time after their treatment started. The details of the three cases are described in this paper.- - - - - - - - - - ranking = 1.7787517752119keywords = leprosy (Clic here for more details about this article) |
4/31. A case of isolated tuberculoid leprosy of antebrachial medial cutaneous nerve.leprosy is an infectious disease of prevalence still high in endemic areas in brazil. The neurological presentation depends on the involved nerve and is usually associated with skin lesions and the formation of multiple abscesses. We present a case of isolated tuberculoid leprosy, discuss the occurrence, the differential diagnosis and the treatment of this rare presentation and reaffirm the importance of considering leprosy in the differential diagnosis of patients with polyneuropathy or nerve enlargement with no skin lesions.- - - - - - - - - - ranking = 0.8209623577901keywords = leprosy (Clic here for more details about this article) |
5/31. leprosy in a backpacker.leprosy is the most common cause of peripheral neuropathy in the developing world. It is not expected to be acquired by visitors traveling through these countries. We present a backpacker who contracted leprosy during brief stays in endemic countries.- - - - - - - - - - ranking = 0.13682705963168keywords = leprosy (Clic here for more details about this article) |
6/31. Pure neural leprosy presenting with multiple nerve abscesses.A 22-year-old male student presented to us with patchy sensory loss over the dorsum of right foot of 6 months' duration and swelling over the left index finger of 2 months' duration. Subsequently, a week later, he developed a painful swelling over the left forehead and right leg. On examination, tender soft, fluctuant subcutaneous saccular swellings were seen varying in size from 2x2 cm to 5x5 cm over the left supratrochlear, left radial cutaneous nerve, left digital nerve, right superficial peroneal nerve and left saphenous nerve. The nerves were tender and thickened above and below these cold swellings (cold nerve abscesses). Nerve biopsy of the left radial cutaneous nerve showed granulomatous infiltrate of epithelioid cells, lymphocytes and caseation necrosis of nerve. No bacilli were demonstrated with acid-fast stain. On the basis of the above findings, a diagnosis of pure neuritic leprosy (BT spectrum) in type 1 lepra reaction with multiple nerve abscesses was made. We present this case of pure neuritic leprosy exhibiting multiple nerve abscesses, for its rarity.- - - - - - - - - - ranking = 0.8209623577901keywords = leprosy (Clic here for more details about this article) |
7/31. Progressive systemic sclerosis (scleroderma). First case report in a Nigerian.The first case of progressive systemic sclerosis in a Nigerian is described. In addition to the typical features of the disease, the case shows affection of the peripheral nerves, a very rare complication. The latter led to a mistaken diagnosis of leprosy. The reasons for the rarity of this disorder in the indigenous Africans and its differentiating features from leprosy are discussed.- - - - - - - - - - ranking = 0.27365411926337keywords = leprosy (Clic here for more details about this article) |
8/31. Nerve abscess in lepromatous leprosy. A case report and a discussion of pathogenesis.An instance of nerve abscesses developing in a patient with lepromatous leprosy is reported. The pathogenesis of nerve abscess in lepromatous leprosy is briefly discussed. It appears that such abscesses may develop (i) from an ENL lesion in the nerve during ENL reaction, (ii) because of exacerbation of existing lepromatous lesion, (iii) arise as an "exacerbation nodule", (iv) due to quiet necrosis in a lepromatous granuloma, or (v) it may be iatrogenic.- - - - - - - - - - ranking = 1.05967921407keywords = leprosy, lepromatous (Clic here for more details about this article) |
9/31. Multiple mononeuropathy in lymphomatoid granulomatosis: similarity to leprosy.Multiple mononeuropathy and anesthetic granulomatous skin lesions were the first manifestations of lymphomatoid granulomatosis in a young woman. The skin lesions resembled those of leprosy. lymphomatoid granulomatosis is related to midline granulomas and other idiopathic granulomatous angiitic lesions.- - - - - - - - - - ranking = 0.68413529815842keywords = leprosy (Clic here for more details about this article) |
10/31. Giant nerve abscesses in leprosy.Two leprosy patients with neuritis caused by giant abscesses involving almost the entire ulnar nerve are described. One patient, who also had skin lesions, was diagnosed histopathologically as having borderline tuberculoid leprosy both on skin and nerve biopsy, and the other, with only nerve involvement, belonged to the pure neuritic group. The lepromin test was strongly positive (with a vesicular reaction in one patient) and lymphocyte transformation to mycobacterium leprae antigen was raised. These lesions can be easily mistaken for a peripheral nerve tumour in places where leprosy is uncommon. A brief account of the management of nerve abscess in leprosy is given.- - - - - - - - - - ranking = 1.0946164770535keywords = leprosy (Clic here for more details about this article) |
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