1/2. Severe hyperphosphatemia and hypocalcemic tetany after oral laxative administration in a 3-month-old infant.A 3-month-old infant presented to the pediatric emergency department with respiratory distress and tetany after ingestion of a phosphate-containing oral laxative. The initial phosphorus level was 38.3 mg/dL. With aggressive fluid resuscitation and intravenous calcium administration, the infant completely recovered. Although the risks of phosphate-containing enemas are well described, life-threatening hyperphosphatemia can also result from administration of phosphate-containing oral laxatives. Aggressive fluid hydration is the mainstay of treatment. Intravenous calcium administration may be necessary to avoid hemodynamic collapse despite the theoretical possibility of metastatic calcifications. physicians should be alerted to the possibility of phosphate toxicity and hypocalcemic tetany in young children when treated with over-the-counter laxatives. caregivers should be advised not to administer over-the-counter laxatives to infants without physician supervision.- - - - - - - - - - ranking = 1keywords = tetany (Clic here for more details about this article) |
2/2. Oral Fleet Phospho-Soda laxative-induced hyperphosphatemia and hypocalcemic tetany in an adult: report of a case.PURPOSE: This study was undertaken to report an adverse outcome of the routine use of Fleets Phospho-Soda for bowel cleansing and to review the available literature. METHOD: Report of a case and review of the literature is presented. RESULT: Administration of Fleets Phospho-Soda for bowel preparation in an adult resulted in hyperphosphatemia and hypocalcemic tetany. review of the literature shows this to be the first such report. Further evaluation suggests a role for partial bowel obstruction and renal failure in this complication. CONCLUSION: Although Fleet Phospho-Soda solution continues to be a safe bowel preparation, caution should be used in adults with bowel obstruction and renal failure.- - - - - - - - - - ranking = 0.83333333333333keywords = tetany (Clic here for more details about this article) |