1/31. prurigo pigmentosa: a misdiagnosed dermatitis in sicily.prurigo pigmentosa is a papular pruriginous eruption that leaves a marble-like pigmentation. The majority of cases have been found in japan. Three new female. Sicilian patients with prurigo pigmentosa were studied. All of them had previously been diagnosed as having different types of dermatitis. The administration of minocycline, at a dosage of 100 mg/day for 1 month, induced the disappearance of the papular eruption and pruritus in two patients, with an improvement of the gross reticular pigmentation. The third showed no modifications of the clinical picture after 2 months of minocycline treatment, but her condition significantly improved after 1 month of treatment with diaminodiphenylsulfone, 100 mg/day. These observations allow us to suggest that prurigo pigmentosa might be relatively frequent but misdiagnosed in the Sicilian population.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
2/31. Dermatosis in a child with kwashiorkor secondary to food aversion.kwashiorkor is a common affliction of children worldwide. It occurs less often in developed countries, but has been reported under a variety of circumstances, including poverty, neurologic disease, and malabsorption. Because of its rare occurrence in the united states and because the affected child has an edematous rather than wasted appearance, physicians often do not consider it as a diagnostic entity. This article describes a case of kwashiorkor in a child with food aversion that manifested as "flaky paint dermatitis." Our discussion will attempt to delineate underlying conditions that may predispose to kwashiorkor. In addition, biochemical and cellular etiologic factors that may be linked with classical and nonclassical skin findings of kwashiorkor are considered. Finally, we present a differential diagnosis for any child with a generalized eczematous or desquamative rash. Our aim is to increase the ability of health care providers to identify and treat children with kwashiorkor in a timely manner.- - - - - - - - - - ranking = 0.2keywords = dermatitis (Clic here for more details about this article) |
3/31. keratosis lichenoides chronica: marked response to calcipotriol ointment.keratosis lichenoides chronica (KCL) is a rare dermatosis characterized by a distinctive seborrheic dermatitis-like facial eruption, together with violaceous, papular, and nodular lesions on the extremities and trunk, typically arranged in a linear and reticulate pattern. KLC is resistant to therapy, although spontaneous remission has been reported. We describe a 35-year-old woman with KLC who had the typical features of widespread violaceous, reticulate, and striae-like eruptions with a prominent keratotic component over a nine-year period and who responded well to treatment with calcipotriol ointment. The immunohistochemical profiles are presented in addition to typical histopathologic features.- - - - - - - - - - ranking = 0.2keywords = dermatitis (Clic here for more details about this article) |
4/31. An ultrastructural study of pigmented purpuric dermatitis with special reference to fibrous long-spacing collagen.A case of pigmented purpuric dermatitis (PPD) in a Japanese man aged 59 years is reported with an interesting ultrastructural finding. Clinically, the lesions, which consisted of telangiectatic puncta and pigmentation, were irregular in shape and occurred predominantly on the lower legs without pruritus. Histologically, lymphocytic perivascular infiltrates and extravasation of red blood cells were observed in the papillary dermis. Ultrastructurally, endothelial cells with ovoid nuclei showed swelling and the lumen of the capillary became narrowed. Several banded structures, so-called fibrous long-spacing collagen (FLSC), were observed in the cytoplasm. They were spindle shaped, about 5 microm in length, and showed crossbands of 300-nm-wide intervals with fine intraperiodic bands. These structures were not observed in dermal connective tissue and fibroblasts. These results suggested that FLSC was synthesized in endothelial cells rather than being phagocytosed by endothelial cells, which might be helpful in investigating the etiology of PPD.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
5/31. Lichen aureus.Lichen aureus is a localized variant of pigmented purpuric dermatitis (PPD) and is rarely reported. A case of lichen aureus in a 28-year-old woman and a 13-year-old boy are presented. biopsy results revealed the characteristic pattern of lichen aureus, including diffuse deposition of hemosiderin and dermal infiltrate of lymphocytes and histiocytes, some of which had Birbeck granules in the cytoplasm. The former case is unusual for its zosteriform distribution and localization (lower abdomen).- - - - - - - - - - ranking = 0.2keywords = dermatitis (Clic here for more details about this article) |
6/31. Monoclonal rearrangement of the T cell receptor gamma-chain in lichenoid pigmented purpuric dermatitis of gougerot-blum responding to topical corticosteroid therapy.Lichenoid pigmented purpuric dermatitis of Gougerot-Blum belongs to a group of closely related disorders which are termed pigmented purpuric dermatoses. It clinically manifests itself with grouped lichenoid papules in association with purpuric lesions. We report a case of lichenoid pigmented purpuric dermatitis of Gougerot-Blum with a heavy band-like CD4-positive lymphocytic infiltrate and clonal rearrangements of the gamma-chain of the T cell receptors as detected by polymerase chain reaction/denaturing gradient gel electrophoresis. Monoclonal expansion of T cells in combination with certain histological features of mycosis fungoides (MF) might support a biological relationship between lichenoid pigmented purpuric dermatitis of Gougerot-Blum and MF. However, prompt clinical response to topical steroid therapy supports the benign clinical nature of our case.- - - - - - - - - - ranking = 1.4keywords = dermatitis (Clic here for more details about this article) |
7/31. Chronic actinic dermatitis with vitiligo-like depigmentation.This report describes two patients suffering from severe chronic actinic dermatitis. Unusual widespread vitiligo-like depigmentation occurred during the course of the disease. The progression of these lesions was triggered by the chronic actinic dermatitis. Loss of pigment and complete absence of tyrosinase positive melanocytes were found in depigmented skin of both cases. Immunohistological investigation of the inflammatory infiltrate in case 2 revealed a predominance of CD-8 positive cytotoxic/-suppressor lymphocytes. Analysing the adjacent pigmented epidermis of progressive depigmenting lesions a dense exocytosis of CD-8 T-cells was notable. This distribution suggests cytotoxic destruction of melanocytes as the cause for the vitiligo-like depigmentation.- - - - - - - - - - ranking = 1.2keywords = dermatitis (Clic here for more details about this article) |
8/31. Pigmented purpuric stomatitis.The pigmented purpuric dermatoses are a group of disorders in which there is chronic capillaritis, with pigmented purpuric lesions predominantly on the lower limbs. We report a case with chronic oral lesions that had histologic features most in keeping with the purpuric lichenoid dermatitis of Gougerot and Blum syndrome.- - - - - - - - - - ranking = 0.2keywords = dermatitis (Clic here for more details about this article) |
9/31. Fatal intra-alveolar hemorrhage after rituximab in a patient with non-Hodgkin lymphoma.A 65-year-old male developed progressive dry cough and digital clubbing after starting rituximab-CHOP chemotherapy for non-Hodgkin lymphoma. A lung biopsy showed loose non-necrotic granulomas in a background of mild fibrosis and rare eosinophils, compatible with a drug-induced hypersensitivity pneumonia. Associated manifestations of this hypersensitivity reaction were a high eosinophil count, elevated serum levels of immunoglobulin e, and a skin rash consistent with pigmented purpuric dermatitis (Schamberg disease). Corticosteroids were marginally efficacious in treating this reaction. Few similar reactions have since been described, 2 of them ultimately fatal, but none was associated with pulmonary hemorrhage. A 2.5:1 ratio between the interstitial alveolar T4/T8 lymphocytes in our case is similar to the findings in methotrexate-induced pneumonitis and farmer lung disease. This report documents the serologic and immunohistologic findings associated with a pulmonary interstitial reaction to rituximab. A review of the pertinent literature is provided. The possible pathogenetic mechanisms, including the role of cytokines, cytotoxic t-lymphocytes and CD 20 positive T-cells in relation to the administration of rituximab are discussed.- - - - - - - - - - ranking = 0.2keywords = dermatitis (Clic here for more details about this article) |
10/31. incontinentia pigmenti achromians (Ito) in a West African.incontinentia pigmenti achromian is a very rare cutaneous disorder of pigmentation which has been reported from japan, the united states of America, the Caribbean countries, mexico and india. A case with coarse hair and associated with atopic dermatitis in a West African girl is presented in this brief report. The case, to the authors' knowledge, is the first documented in africa.- - - - - - - - - - ranking = 0.2keywords = dermatitis (Clic here for more details about this article) |
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