1/5. Limited infection upon human exposure to a recombinant raccoon pox vaccine vector.A laboratory accident resulted in human exposure to a recombinant raccoon poxvirus (RCN) developed as a vaccine vector for antigens of yersinia pestis for protection of wild rodents (and other animals) against plague. Within 9 days, the patient developed a small blister that healed within 4 weeks. Raccoon poxvirus was cultured from the lesion, and the patient developed antibody to plague antigen (F1) and RCN. This is the first documented case of human exposure to RCN.- - - - - - - - - - ranking = 1keywords = wild (Clic here for more details about this article) |
2/5. Human bubonic plague transmitted by a domestic cat scratch.Bubonic plague was transmitted to a 10-year-old girl in oregon by a scratch wound inflicted by a domestic cat. The cat probably was infected by contact with infected wild rodents or their fleas. yersinia pestis was identified in Diamanus montanus fleas collected from an abandoned burrow near the patient's home. Domestic cats may infect humans with Y pestis by inoculation from a scratch.- - - - - - - - - - ranking = 1keywords = wild (Clic here for more details about this article) |
3/5. Peripatetic plague.Cases of plague continue to occur in various parts of the world, including the western united states, where plague is endemic among the wild rodent population. In 1980, a case of plague acquired in new mexico and hospitalized in nebraska illustrated the problem of plague occurring in persons traveling from the state in which they become infected to another state. Nine cases of plague in travelers were identified among the 166 cases of plague reported in the united states from 1950 to 1980. physicians should be aware of natural plague foci in the western united states and should obtain a travel history from patients with an illness clinically compatible with plague.- - - - - - - - - - ranking = 1keywords = wild (Clic here for more details about this article) |
4/5. An overview of plague in the united states and a report of investigations of two human cases in Kern county, california, 1995.plague was confirmed in the united states from nine western states during 1995. Evidence of yersinia pestis infection was identified in 28 species of wild or domestic mammals. Thirteen of the plague positive species were wild rodents; 15 were predators/carnivores. yersinia pestis was isolated from eight species of fleas. Seven confirmed cases of human plague were reported in 1995 (new mexico 3; california 2; arizona and oregon 1 each). Five of the seven cases were bubonic; one was septicemic and one a fatal pneumonic case. Months of onset ranged from March through August. In california, during 1995, plague was recorded from 15 of the 58 counties. Over 1,500 animals were tested, of which 208 were plague positive. These included 144 rodents and 64 predators/carnivores. Two confirmed human cases (one bubonic and one fatal pneumonic) occurred, both in Kern County. Case No. 1 was reported from the town of Tehachapi. The patient, a 23 year-old male resident, died following a diagnosis of plague pneumonia. The patient's source of plague infection could not be determined precisely. Field investigations revealed an extensive plague epizootic surrounding Tehachapi, an area of approximately 500-600 square miles (800-970 square kilometers). Case No. 2 was a 57 year-old female diagnosed with bubonic plague; she was placed on an antibiotic regimen and subsequently recovered. The patient lives approximately 20 miles (32 km) north of Tehachapi. Field investigations revealed evidence of a plague epizootic in the vicinity of the victim's residence and adjacent areas. overall results of the joint field investigations throughout the entire Kern county area revealed a high rate of plague positive animals. Of the numerous samples submitted, 48 non-human samples were plague positive.- - - - - - - - - - ranking = 2keywords = wild (Clic here for more details about this article) |
5/5. Bubonic plague from exposure to a rabbit: a documented case, and a review of rabbit-associated plague cases in the united states.A 62-year-old woman developed bubonic plague with an epitrochlear bubo one to two days after skinning two cottontail rabbits. The implicated rabbits were later recovered from the patient's freezer, and yersinia pestis was isolated from marrows of both rabbits. Although human plague cases in the united states have occasionally been traced to exposure to wild rabbits, this is the first documentation of plague infection in the actual rabbits to which the patient was exposed. All reported cases of rabbit-associated plague in the united states were then reviewed. Eight cases were characterized by direct exposure to rabbit tissues. Seven of the eight cases occurred in adult males who had hunted rabbits during winter months in plague-endemic areas. These patients had upper extremity buboes, and the case-fatality ration for the group was 50%. Three other cases in which rabbit exposure was indirect or its role less clear, were also analyzed.- - - - - - - - - - ranking = 1keywords = wild (Clic here for more details about this article) |