1/59. Persistent pneumatoceles associated with systemic leukocyte abnormalities.Three patients with leucocyte related immune deficiency developed pneumatoceles during acute bacterial pneumonia. A fourth patient with chronic granulomatous disease of childhood developed persistent lung cysts following pulmonary abscesses. The pneumatoceles persisted without significant change for one year to five years. In 25 immunologically normal patients, pneumatoceles that were associated with acute bacterial pneumonia resolved in 3 weeks to 11 months. Perhaps alterations in leukocytic function and in local inflammatory response result in fibrotic cellular reaction and sequestration of parenchymal air collections, precluding their resorption.- - - - - - - - - - ranking = 1keywords = pneumonia (Clic here for more details about this article) |
2/59. Spontaneous tension pneumopericardium complicating staphylococcal pneumonia.The authors describe a patient with spontaneous pneumopericardium complicating staphylococcal pneumonia and empyema that resulted in cardiac tamponade. Spontaneous pneumopericardium is an unusual disorder. The causes and clinical findings of pneumopericardium are reviewed, as are the radiographic features that differentiate this condition from pneumomediastinum. Early recognition of pneumopericardium is important, because emergent pericardiocentesis may be required if there is clinical evidence of tamponade.- - - - - - - - - - ranking = 25246.794359976keywords = staphylococcal pneumonia, pneumonia (Clic here for more details about this article) |
3/59. Moderate-dose intravenous immunoglobulin treatment of Job's syndrome. Case report.Job's syndrome (or hyperimmunoglobulinemia E syndrome) is a rare genetic disease characterized by skin eczema, pyogenic "cold" abscesses, sinopulmonary recidivous infections and high IgE plasma concentrations. Job's syndrome treatment is not satisfactory and cases studied are still limited. To describe the effects of IVIG therapy in a 37-year-old woman with hyper IgE syndrome and pneumonia. We measured IgE serum by immuno-fluorometric test and neutrophil chemotaxis by migration in a Boyden chamber before and after IVIG therapy. A moderate dose of IVIG resolved the clinical-radiological signs of the S. aureus bronchopneumonia and improved cytologic and biohumoral parameters. Intravenous immunoglobulins represent a useful treatment for acute pneumonia in Job's syndrome.- - - - - - - - - - ranking = 1.5keywords = pneumonia (Clic here for more details about this article) |
4/59. Primary staphylococcal infection and toxic shock syndrome diagnosed by polymerase chain reaction.Primary staphylococcal pneumonia complicated with toxic shock syndrome (TSS) is relatively uncommon in children. Staphylococcus aureus exotoxins are thought to function as superantigens, and seem to promote disease manifestations. The identification of staphylococcal toxin genes by polymerase chain reaction (PCR) offers a specific and rapid diagnostic method for TSS. We describe a 7-year-old child with TSS resulting from staphylococcal pneumonia. S. aureus enterotoxins A and B were detected in the sputum of this patient by PCR.- - - - - - - - - - ranking = 10098.71774399keywords = staphylococcal pneumonia, pneumonia (Clic here for more details about this article) |
5/59. breast milk transmission of a Panton-Valentine leukocidin-producing Staphylococcus aureus strain causing infantile pneumonia.We report on a 38-day-old infant who developed pleuropneumonia due to a Staphylococcus aureus strain responsible for familial furunculosis, which was acquired by maternal breast-feeding. All isolates from the infant and parents were genetically related by randomly amplified polymorphic dna analysis and produced Panton-Valentine leukocidin.- - - - - - - - - - ranking = 2.5keywords = pneumonia (Clic here for more details about this article) |
6/59. Treatment of acrodermatitis continua of Hallopeau with oral propylthiouracil and methotrexate.A 71-year-old man with acrodermatitis continua of Hallopeau was treated successfully with a combination of oral propylthiouracil and methotrexate. After 14 weeks, he developed acute pancytopenia, an uncommon idiosyncratic side-effect of propylthiouracil, and presented with a life-threatening methicillin-resistant Staphylococcus aureus pneumonia. This illustrates the potential value and associated risks of propylthiouracil in the management of this difficult condition.- - - - - - - - - - ranking = 0.5keywords = pneumonia (Clic here for more details about this article) |
7/59. Chronic plasma cell pneumonia in a patient with long-standing hiv infection.Chronic bibasilar alveolar infiltrates existed for more than 2 years in a 25-year-old woman infected with hiv for more than a decade. Bronchoscopically, there were copious, purulent secretions that grew methicillin-resistant staphylococcus aureus (MRSA). Transbronchial biopsy specimens demonstrated plasma cell interstitial pneumonia (PCIP). Focal, transient radiographic improvement occurred after antistaphylococcal antimicrobial therapy. With recurrent and progressive symptoms, sustained clinical and radiographic improvement did not occur until corticosteroid therapy was instituted with tuberculosis chemoprophylaxis. Persistent antigenic stimulation in immunosuppressed patients causes PCIP. In this instance, the stimulus is MRSA. The previous model and support for this theory is pneumocystis carinii. There is good experimental reason for a plasma cell response in persons infected with hiv. To our knowledge, this is the first case of chronic plasma cell interstitial pneumonia caused by indolent MRSA infection.- - - - - - - - - - ranking = 3keywords = pneumonia (Clic here for more details about this article) |
8/59. Intrafamilial spread of highly virulent staphylococcus aureus strains carrying the gene for Panton-Valentine leukocidin.Necrotizing pneumonia caused by Staphylococcus aureus carrying the gene for Panton-Valentine leukocidin is a newly described disease entity. We report 2 cases with intrafamilial spread.- - - - - - - - - - ranking = 0.5keywords = pneumonia (Clic here for more details about this article) |
9/59. life-threatening hemoptysis in adults with community-acquired pneumonia due to Panton-Valentine leukocidin-secreting Staphylococcus aureus.Three new consecutive cases of life-threatening hemoptysis in adults with community-acquired pneumonia due to Panton-Valentine leukocidin-secreting Staphylococcus aureus are presented, focusing on the particular clinical presentation of this new entity. Between December 1999 and March 2001, three adults aged from 23 to 67 years were admitted to our respiratory intensive care unit for massive hemoptysis and septic shock associated with community-acquired Staphylococcus aureus pneumonia. Isolates were sent to the Centre National de Reference des Toxemies Staphylococciques in Lyon, france, where they were found to secrete Panton-Valentive leukocidin. The clinical course was similar in the three patients, with massive hemoptysis and septic shock necessitating mechanical ventilation. Two patients died rapidly; necropsy showed pulmonary vascular necrosis in one of them. The third patient recovered after appropriate antibiotic therapy. Leukocidin/neutrophil interactions in the pulmonary vasculature may cause severe hemoptysis in patients with community-acquired Staphylococcus aureus pneumonia secreting Panton-Valentine leukocidin. adult patients with massive hemoptysis and suspected community-acquired pneumonia should receive antibiotic regimens covering Staphylococcus aureus.- - - - - - - - - - ranking = 4keywords = pneumonia (Clic here for more details about this article) |
10/59. Prosthesis endocarditis: treatment of a case occurring five years after a Rastelli-Ross operation.A severe staphylococcal septicemia originating from an unknown focus occurred in a 17-year-old patient who had undergone a Rastelli-Ross operation 5 years earlier. The clinical course was complicated by extensive bilateral pneumonia, diffuse intravascular coagulation, and glomerulonephritis. After 4 weeks of intensive conservative treatment, including a daily regimen of 16 Gm. of cloxacillin, the patient was operated upon for a rapidly progressive false aneurysm, which had resulted from dehiscence of the anastomosis between the prosthesis and ventricle. The excised prosthesis proved to be sterile. The postoperative course was uneventful. cloxacillin treatment was continued for 6 months, initially parenterally and later orally. After discontinuation of therapy, no signs of infection have occurred. Right-sided intracardiac or intravascular prosthetic material may be particularly susceptible to infections originating from the body surface.- - - - - - - - - - ranking = 0.5keywords = pneumonia (Clic here for more details about this article) |
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