1/6. "White dots on the placenta and red dots on the baby": congential cutaneous candidiasis--a rare disease of the neonate.Cutaneous congenital candidiasis (CCC) is a very rare disease of the term or premature infant consisting of a generalized rash at or shortly after birth usually without other signs or symptoms. The presence of white microabscesses on the placenta and umbilical cord of an infant with such a rash must suggest the diagnosis of CCC, which is always secondary to candida chorioamnionitis but may pass unrecognized. Despite the high prevalence of vulvo-vaginitis in pregnant women, candida chorioamnionitis is rare and CCC remains apparently extremely rare with just some hundred cases described. However, as the condition is essentially benign and self-limited, underdiagnosis is likely. As occasional systemic spread of candida infection is described and maternal complications may arise, diagnosis and a close follow-up or treatment is of importance. We present two cases of CCC, stressing the importance of sharing clinical findings between obstetrician and neonatologist for the diagnosis and subsequent management.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/6. Congenital pulmonary tuberculosis associated with maternal cerebral tuberculosis--florida, 2002.In 2002, congenital tuberculosis (TB), a rare disease with nonspecific signs and symptoms, was diagnosed in an infant in florida. If untreated, congenital TB is fatal, which underscores the importance of suspecting congenital TB in newborns and infants who are at risk and who have unexplained febrile illnesses. This report summarizes the investigation of the case in florida. health-care practitioners should administer a tuberculin skin test to women who have risks for mycobacterium tuberculosis infection and treat those who have latent TB infection (LTBI) to prevent maternal and congenital TB disease.- - - - - - - - - - ranking = 0.2keywords = rare disease (Clic here for more details about this article) |
3/6. Nocardial tubo-ovarian abscess in a pregnant woman: a rare case report.Nocardiosis is a rare disease associated with significant morbidity and mortality in immunocompromised patients. We report on a 32-year-old pregnant woman with nocardiosis, which may be the third reported case in which no risk factor for the infection (other than the pregnancy itself) could be found. pregnancy was complicated by the formation of a tubo-ovarian nocardia abscess, resulting in abortion. Lapartomy with trimethopprim-sulfamethoxazole led to complete cure of the patient at the end of the fifth month. This case emphasizes the difficulty in the diagnosis and treatment of a nocardial infection during pregnancy.- - - - - - - - - - ranking = 0.2keywords = rare disease (Clic here for more details about this article) |
4/6. Parenteral and oral acyclovir for management of varicella pneumonia in pregnancy: a case report with review of literature.Varicella pneumonia is a relatively rare disease in the reproductive-aged woman, but has a reported 41 percent maternal mortality rate in pregnancy. Seventeen cases managed with intraveneous acyclovir are reviewed. We report successful management with the unpublished addition of oral acyclovir to complete antiviral therapy on an outpatient basis.- - - - - - - - - - ranking = 0.2keywords = rare disease (Clic here for more details about this article) |
5/6. Fetal immune response following maternal diphtheria during early pregnancy.A pregnant Sudanese woman contracted pharyngeal diphtheria during the first trimester of gestation. She had a severe diphtheritic toxaemia and paralysis of all four limbs but made a full recovery from these manifestations. pregnancy, apart from vaginal bleeding, was not interrupted. At term she was delivered of a female baby who was physically normal but had a very high level of IgA in cord blood. Diphtheria in adults is a rare disease and the occurrence of diphtheria in a pregnant woman has not, as yet, been reported. Accordingly it is not known how fetal growth and development progress in the presence of diphtheria toxin in the maternal circulation. Similarly the effects on fetal immune responses of an acute maternal infection like diphtheria occurring in early pregnancy are not known.- - - - - - - - - - ranking = 0.2keywords = rare disease (Clic here for more details about this article) |
6/6. Meliodosis.During the five-month wet season of 1977-1978 in Northern queensland, six patients with bacteriologically proven melioidosis were successfully treated at the Townsville General Hospital, The clinical course and management of each case and laboratory findings are described. Factors which predisposed them to infection with pseudomonas pseudomallei were diabetes mellitus, cancer, alcoholism, malnutrition, trauma, and pregnancy. Successful treatment of melioidosis relied on prompt laboratory diagnosis and appropriate chemotherapy together with surgical drainage of abscesses and management of concomitant diseases. The incidence of melioidosis in Northern queensland has increased to the extent that it can no longer be considered a rare disease in this area. Because of increased internal and international travel, and displacement of refugees from endemic areas of Southeast asia, physicians and microbiologists must maintain a high index of suspicion of melioidosis when dealing with patients after geographic exposure, as it is probable that, in the future, this disease witll be encountered more frequently in non-endemic areas.- - - - - - - - - - ranking = 0.2keywords = rare disease (Clic here for more details about this article) |