1/14. Fetal cataract in congenital toxoplasmosis.We report a case of the prenatal diagnosis of fetal cataract due to congenital toxoplasmosis. To the best of our knowledge, this is the first report of such a case. We discuss the long-term ocular sequelae of the condition and how they should affect prenatal counselling.- - - - - - - - - - ranking = 1keywords = toxoplasmosis, ocular (Clic here for more details about this article) |
2/14. toxoplasmosis. Are cats really the source?BACKGROUND: toxoplasmosis is a zoonotic infection caused by the parasite toxoplasma gondii. It would appear to be one of the commonest human infections, but is usually asymptomatic. It is only problematic if the patient is pregnant or immunosuppressed. OBJECTIVE: To discuss the epidemiology, clinical features, diagnosis, treatment and prevention of toxoplasmosis. DISCUSSION: cats have long been blamed for playing a major role as the reservoir of this infection. To some extent, this is true, although contact with infected raw meat is probably a more important cause of human infection in many countries. Direct contact with pet cats is also a less common risk factor for infection than ingestion of the oocyst from faecally contaminated hands (often via soil).- - - - - - - - - - ranking = 0.19999604061903keywords = toxoplasmosis (Clic here for more details about this article) |
3/14. Primary toxoplasma gondii infection in a pregnant human immunodeficiency virus-infected woman.We report a 36-year-old hiv-infected woman who developed primary toxoplasma gondii infection during pregnancy that was treated with spiramycin and antiretroviral drugs. There was no vertical transmission of toxoplasmosis and hiv.- - - - - - - - - - ranking = 0.19999604061903keywords = toxoplasmosis (Clic here for more details about this article) |
4/14. toxoplasmosis transmitted to a newborn from the mother infected 20 years earlier.PURPOSE: To present a case of congenital toxoplasmosis in a newborn whose mother had a 20-year history of a chorioretinal macular scar and positive serology for toxoplasmosis. DESIGN/methods: Case report. SETTING/RESULTS: A 38-year-old woman who had been treated for ocular toxoplasmosis 20 years earlier delivered a newborn who presented with a focal necrotizing retinochoroiditis characteristic of toxoplasmosis, as well as positive immunoglobulin (Ig) G and M serology for toxoplasmosis. The workup was negative for other entities. CONCLUSION: This case suggests that women with old retinal scars due to toxoplasmosis and long-standing IgG antibodies to toxoplasmosis are also at risk of transmitting this disease to the fetus.- - - - - - - - - - ranking = 1.543744916434keywords = toxoplasmosis, ocular toxoplasmosis, ocular (Clic here for more details about this article) |
5/14. Vertical transmission of toxoplasmosis from a chronically infected immunocompetent woman.We report the vertical transmission of congenital toxoplasmosis from a chronically infected immunocompetent woman to her child. On the background of published knowledge in this field, vertical transmission must have developed after maternal reinfection or reactivation of the preexisting disease.- - - - - - - - - - ranking = 0.99998020309514keywords = toxoplasmosis (Clic here for more details about this article) |
6/14. Severe neonatal toxoplasmosis after third trimester maternal infection.We report an unusual case of neonatal toxoplasmosis. After a late third trimester maternal infection, the infant developed severe disseminated intravascular coagulopathy with thrombocytopenia, hepatitis, jaundice and severe pneumonitis. Clinicians that manage infants with severe unexplained systemic disease should consider the possibility of congenital toxoplasmosis.- - - - - - - - - - ranking = 1.1999762437142keywords = toxoplasmosis (Clic here for more details about this article) |
7/14. Granulomatous villitis formed by inflammatory cells with maternal origin: a rare manifestation type of placental toxoplasmosis.We present a case of placental toxoplasmosis with granulomatous villitis. The patient was a 26-year-old gravida 1 female with the findings of intrauterine death at 16th week of gestation. The pregnancy was terminated. Pathological examination revealed an autolysed fetus and a placenta with necrotizing granulomas within the villous stroma. Encysted toxoplasma gondii was rarely observed within the granulomas and serologic examination of the mother confirmed acute toxoplasmosis. A fluorocein in situ hybridization examination, using sex chromosome probes, revealed that the villous granulomas were formed by inflammatory cells, originated from the maternal immune system. In conclusion, T. gondii should be taken into consideration as a rare cause of placental granulomatous inflammation. To the best of our knowledge, this is the first case of granulomatous villitis due to toxoplasmosis, in which formation by maternal inflammatory cells has been demonstrated.- - - - - - - - - - ranking = 1.3999722843332keywords = toxoplasmosis (Clic here for more details about this article) |
8/14. brain metastasis of alveolar echinococcosis in a hyperendemic focus of echinococcus multilocularis infection.An unusual female case, with alveolar echinococcosis (AE) disseminated from the primary hepatic lesion to the brain by metastasis formation, was retrospectively identified during a community survey in Ningxia Hui Autonomous Region, northwest china in 2003. Among possible metastases of hepatic AE, locations to the brain are rare and usually fatal; and they have especially been assigned to concomitant immune suppression. An enhancing role of pregnancy, which may be suspected in this case, the favourable outcome after surgery and chemotherapy, and also a mental disability in a child following long-term intrauterine exposure to mebendazole, make the report particularly unique.- - - - - - - - - - ranking = 7.9187619438319E-5keywords = ocular (Clic here for more details about this article) |
9/14. Ocular toxoplasmosis in pregnancy.PURPOSE: To describe the course of ocular toxoplasmosis during pregnancy. methods: This study was a retrospective, non-comparative case series of four pregnant women who were treated for ocular toxoplasmosis during pregnancy. RESULTS: All of the participants had severe and treatment-resistant toxoplasmic retinochoroiditis during pregnancy, leaving three of them with decreased visual acuity in spite of aggressive therapy. Delivery of the infant appeared to help the recovery in two patients. CONCLUSIONS: Pregnant state may provoke the recurrence of ocular toxoplasmosis.- - - - - - - - - - ranking = 1.8312901806357keywords = toxoplasmosis, ocular toxoplasmosis, ocular (Clic here for more details about this article) |
10/14. Ocular toxoplasmosis in the fetus. immunohistochemistry analysis and dna amplification.PURPOSE: Ocular toxoplasmosis is often the result of a congenital infection. However, the earlier stages of the ocular lesions in the fetus have not been well studied. The purpose of the present study is to analyze the ocular findings in four aborted fetuses that were infected congenitally with toxoplasma gondii. methods: Eight eyes from four fetuses of 22 to 27.5 weeks with T. gondii infection were studied by routine and immunohistochemical techniques. Two of the four were also examined by polymerase chain reaction (PCR). RESULTS: In two cases, the results of gross and histopathologic of the eyes were normal; marked retinal necrosis was present in the other two cases. Although no toxoplasmic cysts were identified by routine histopathologic examination, antigens of the tachyzoite were detected by immunohistochemistry analysis in the areas of retinal necrosis. In one of the cases with ocular lesions, the presence of T. gondii was confirmed by PCR. The presence of ocular lesions correlated with the severity of pathologic changes in the central nervous system. Large numbers of T cells were observed in the retinal lesions and in the choroid. CONCLUSION: Retinal necrosis, neovascularization, and marked chorioretinal inflammations despite the absence of bradyzoites are characteristic findings in the fetal eyes infected with T. gondii, and infiltrating T lymphocytes play a role in early recognition of the toxoplasma organism.- - - - - - - - - - ranking = 1.0000593907146keywords = toxoplasmosis, ocular (Clic here for more details about this article) |
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