1/23. Oral giant pyogenic granulomas associated with facial skin hemangiomas (sturge-weber syndrome).This is a case report of two patients, aged 26 and 22, who suffered from congenital hemangioma on their faces and pronounced gingival overgrowth localized parallel to extraoral lesions. Prior to surgical intervention the hygienic conditions were improved in several sessions by means of professional preventive treatment and oral hygiene instructions. Histologic examination of both cases revealed a highly vascularized pattern of pyogenic granuloma. One of the cases was associated with a pregnancy. These patients can be classified as sturge-weber syndrome. Postsurgical treatment consisted of efficient plaque control and adequate oral prophylaxis sessions every 3 months. The large gingival overgrowth was not observed to recur in 2 and 4 years, respectively, of follow-up.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/23. Rapid growth of giant cell granuloma in pregnancy treated with calcitonin.The giant cell granuloma of the jaws is a benign osteolytic lesion that may be treated by curettage, intralesional corticosteroids, or calcitonin. These medical treatments may be particularly useful when lesions arise in the immature facial skeleton, recur, or enlarge very rapidly-the last two situations being recognized complications of pregnancy. In this study, a patient is presented with a central giant cell lesion of the maxilla that switched from a relatively indolent growth pattern to become a rapidly enlarging and destructive lesion in the maxilla almost immediately after the patient became pregnant. Although calcitonin treatment is normally avoided in pregnancy, it proved highly effective, caused no obstetric or fetal side effects, and was not contraindicated by renal failure due to lupus nephritis. Histologically, the lesion was converted to a fibro-osseous lesion-like appearance. On the basis of the results of this case, calcitonin appears to be a safe, effective, and conservative treatment for giant cell granulomas that enlarge rapidly during pregnancy.- - - - - - - - - - ranking = 1.75keywords = giant (Clic here for more details about this article) |
3/23. Giant cell myocarditis: a fatal cause of dyspnea in pregnancy.The clinical course of a pregnant patient, who presented with progressive dyspnea and heart failure is described. Despite intensive care and resuscitative efforts to mother and child, both expired. The autopsy revealed giant cell myocarditis in the mother.Giant cell myocarditis can affect pregnant patients and should therefore be considered in the differential diagnosis of progressive dyspnea.- - - - - - - - - - ranking = 0.25keywords = giant (Clic here for more details about this article) |
4/23. chediak-higashi syndrome in pregnancy.We report the first known case of chediak-higashi syndrome in human pregnancy. This rare autosomal recessive disorder is characterized by partial oculocutaneous albinism, decreased leukocyte chemotaxis, susceptibility to infection, and death in childhood. Pathognomonic giant cytoplasmic granules are postulated to be dysfunctional fused lysosomes, which influence a wide range of physiologic processes. pregnancy did not seem to exert any influence on the course of the disease. The pregnancy, labor, and delivery were not affected and the infant and placenta were normal.- - - - - - - - - - ranking = 0.25keywords = giant (Clic here for more details about this article) |
5/23. A case of giant nasal pyogenic granuloma gravidarum.Pyogenic granuloma gravidarum occurs as oral or nasal lesions in approximately 5% of pregnant women. nasal mucosa is an unusual site for this lesion with few cases reported in the literature. A case of giant nasal pyogenic granuloma gravidarum that required radical excision through an open rhinotomy after superselective embolization is described. The patient had a good cosmetic result and a satisfactory airway when she was seen for follow-up 1 year after surgery. Giant pyogenic granuloma gravidarum is best managed with a multidisciplinary approach involving radical excision after preoperative superselective embolization for safe and complete removal of the lesion.- - - - - - - - - - ranking = 1.25keywords = giant (Clic here for more details about this article) |
6/23. giant cell arteritis in a patient with acute aortic insufficiency with thyrotoxicosis.Acute aortic insufficiency in the setting of thyrotoxicosis can mask the presentation of vasculitis. We report a case of a 38-year-old woman with a 22 weeks gestation pregnancy who was known to be hyperthyroid for 4 months prior to conception. She presented with thyrotoxicosis and acute respiratory failure. Echocardiogram revealed severe acute aortic regurgitant flow. Following medical treatment for aortic insufficiency and thyrotoxicosis, the patient underwent ascending aorta replacement with aortic valve repair. Pathological exam revealed giant cell arteritis. Both giant cell arteritis and thyrotoxicosis share a common major histocompatibility antigen which may facilitate concomitant disease presentation. Following immunosuppression for giant cell arteritis, valve repair, and treatment for thyrotoxicosis, the patient made a complete recovery. A rise in human chorionic gonadotropin (HCG) during the first trimester of pregnancy is known to have a stimulatory effect on the thyroid gland and may result in hyperthyroidism. Although HCG may have exacerbated the existing hyperthyroidism, in this case it was not causal, as the diagnosis preceded her pregnancy by several months. diagnosis of vasculitis may be overshadowed by the presence of thyrotoxicosis. Significant vascular compromise in the setting of thyrotoxicosis must prompt an evaluation for vasculitis. This may prevent unnecessary surgery with attendant morbidity and mortality.- - - - - - - - - - ranking = 0.75keywords = giant (Clic here for more details about this article) |
7/23. Giant presacral neuro-enteric cyst with anomalous sacrum in an adult patient.A rare case of an adult patient with a giant neuro-enteric cyst in a presacral location is reported. It had unique histological features of a stratified squamous epithelial lining with neuro-epithelial and smooth muscle components. There was associated sacral dysgenesis with spina bifida. The possible pathogenesis of this entity is discussed.- - - - - - - - - - ranking = 0.25keywords = giant (Clic here for more details about this article) |
8/23. Images in reproductive medicine. A case of giant cystic adenomyosis.We describe a 37-year-old woman with giant cystic adenomyosis who underwent a hysterectomy, providing magnetic resonance imaging and gross and microscopic images.- - - - - - - - - - ranking = 1.25keywords = giant (Clic here for more details about this article) |
9/23. Sellar granulomatous mass in a pregnant woman with active Crohn's disease.At the end of her third pregnancy, a woman with a history of chronic active proctocolitis which had been diagnosed as Crohn's disease complained of deterioration of visual acuity. The patient was found to have hypopituitarism and progressive bitemporal hemianopia caused by an intrasellar mass with suprasellar extension. At transsphenoidal surgery an intrasellar granuloma was found without remnants of pituitary tissue. This sellar granuloma could have been an extra-intestinal granuloma of Crohn's disease. However, the possibility that giant cell granulomatous hypophysitis had been present was considered more likely. The occurrence of this disorder in the postpartum period has not been reported before.- - - - - - - - - - ranking = 0.25keywords = giant (Clic here for more details about this article) |
10/23. Fetal liver disease may precede extrahepatic siderosis in neonatal hemochromatosis.Three children of a mother with biopsy-confirmed posttransfusional hepatitis of undetermined etiology (non-A, non-B hepatitis) died in utero or in infancy. All had liver disease of intrauterine onset. The two liveborn children died of the consequences of severe hepatic insufficiency manifest at birth and met clinicopathologic criteria for neonatal hemochromatosis. Although hepatic architecture in the stillborn fetus was markedly disordered, with hepatocyte giant cell transformation, extrahepatic siderosis was not present and hepatic siderosis was minimal. These findings indicate that in some cases of neonatal hemochromatosis, extrahepatic siderosis may be caused by hepatic injury rather than primarily due to excessive transport of iron from mother to fetus and support speculation that in some instances an infective agent may be responsible.- - - - - - - - - - ranking = 0.25keywords = giant (Clic here for more details about this article) |
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