1/12. prurigo pigmentosa from contact allergy to chrome in detergent.prurigo pigmentosa is a recurrent inflammatory dermatosis characterized by pruritic erythematous papules and reticulate hyperpigmentation that occurs most frequently in spring and summer. The etiology of prurigo pigmentosa remains unknown. Numerous authors have suggested that various contact allergens may be pathogenic or triggering factors, but nearly all attempts to identify an allergen have been unsuccessful. We report a case of prurigo pigmentosa induced by contact allergy to chrome in detergent, supporting the conclusion that contact allergens such as chrome may play a role in inducing prurigo pigmentosa.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
2/12. A case of severe actinic prurigo successfully treated with thalidomide.Actinic prurigo is an uncommon and usually persistent idiopathic photodermatosis with typical human leukocyte antigen (HLA) associations (HLA-DR4, particularly subtypes DRB1*0407 and DRB1*0401). Although its mechanism of action is not clearly understood, thalidomide has been shown to be particularly efficacious in treating actinic prurigo, among other conditions. A 31-year-old Australian woman who had suffered actinic prurigo for most of her life was treated with two courses of thalidomide (50-100 mg nocte) over consecutive summers. Remission was observed after cessation of the second course of thalidomide and had continued 4 years later. Abnormalities in the cutaneous response to ultraviolet radiation at the time of diagnosis, detected by monochromator phototesting, reverted to normal following treatment.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
3/12. prurigo pigmentosa.BACKGROUND: prurigo pigmentosa is a rare inflammatory dermatosis of unknown etiology characterized by recurrent, pruritic erythematous papules and gross reticulate hyperpigmentation. It is seen most commonly among young adult Japanese females. Only 20 cases have been described outside japan. methods: We report two female, Turkish patients aged 20 and 26 years who had a pruritic rash with the characteristic clinical appearance and supportive histopathology of prurigo pigmentosa. RESULTS: They were successfully treated with minocycline and doxycycline. CONCLUSIONS: prurigo pigmentosa is a relatively new clinical entity, and we believe that a more widespread knowledge of this disease will lessen its misdiagnosis. We find it noteworthy to point out that there may be a predisposition to prurigo pigmentosa amongst the Turkish and Sicilian populations.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
4/12. ESRD-associated cutaneous manifestations in a hemodialysis population.Cutaneous manifestations occurring in patients with end stage renal disease (ESRD) can indicate systemic problems that have significant morbidity and mortality risks. skin changes are sometimes a consequence of the disease that caused the renal failure or may be an ESRD manifestation. pruritus is the most prevalent ESRD cutaneous complaint, but its pathogenesis is not understood. The pathophysiology, presentation, and nursing implications of perforating dermatosis, metastatic calcification, polytetraflouroethylene graft infection, and lichen planus are discussed with corresponding case reports.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
5/12. Patch testing in prurigo nodularis.32 patients with prurigo nodularis evaluated at the Mayo Clinic from 1975 to 1987 have been patch tested for sensitivity to appropriate allergen series; 25 of these had relevant positive reactions and subsequent follow-up to 5 to 14 years was available for 11. 6 patients had persistent disease and 5 had resolution or marked improvement. 3 of these latter patients noted a strong positive correlation between improvement and avoidance of contact allergens. Screening for contact sensitivity may be helpful in the management of this refractory dermatosis, particularly if there is a coexistent dermatitis.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
6/12. prurigo pigmentosa.prurigo pigmentosa is a rare dermatosis which is most common in japan. Although the histological features are non-specific, the clinical appearance is striking and is dominated by gross reticular pigmentation. A Chinese patient with prurigo pigmentosa is described.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
7/12. prurigo pigmentosa: a possible mechanism of action of sulfonamides.The patient described here had all the clinical features (itchy red papules and reticular pigmentation) as well as the histological findings (lichenoid tissue reactions) of prurigo pigmentosa, a little-known disorder of unknown etiology, and responded well to sulfamethoxazole treatment. In order to investigate the mode of action of this drug and thus the underlying pathogenesis of this dermatosis, the effect of sulfamethoxazole on the production of oxygen intermediates (OIs) was examined both in the cell-mediated system and in the xanthine-xanthine oxidase system. It was found that therapeutic doses of the drug significantly reduced the hydroxyl radical levels, one of the most potent oxidants that might cause tissue injury. These findings suggest the possibility that OIs produced by infiltrated cells are involved in the inflammatory process of prurigo pigmentosa and that sulfonamides exert their anti-inflammatory effects by affecting OI generation which results in protection against lichenoid tissue reaction.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
8/12. prurigo pigmentosa. Case report with an electron microscopic observation.prurigo pigmentosa is an inflammatory dermatosis characterized by pruritic, reddish, papular lesions and gross reticular pigmentation that occurs mainly on the trunk. Nearly 100 cases have been reported in japan to date. We describe a patient with this condition who responded well to dapsone. An electron microscopic study of the reddish papular lesion showed marked intercellular edema and evidence of cellular injury of the basal cells. Direct immunofluorescence was negative. We stress that this condition is a distinct clinical entity, histologically characterized by a lichenoid tissue reaction as proposed by Pinkus, although it is little known outside japan.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
9/12. prurigo pigmentosa affecting the forehead.A little-known dermatosis, prurigo pigmentosa, is characterized by itchy reddish lesions and gross reticular pigmentation which occurs mainly on the trunk. Histologically, it is characterized by lichenoid tissue reaction. We present a 23-year-old male patient who showed typical eruption not only on the trunk but also on the forehead. Although the etiology remains to be explained, this unusual distribution of the eruption might help to know the real cause of this peculiar disorder.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
10/12. Treatment of prurigo nodularis: use of cryosurgery and intralesional steroids plus lidocaine.Two patients with prurigo nodularis resistant to most modalities of therapy were treated successfully with the combined use of cryosurgery and intralesional steroids plus lidocaine. This appears to be a successful treatment regimen for a dermatosis that is often difficult to control.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
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