1/23. prurigo pigmentosa: a misdiagnosed dermatitis in sicily.prurigo pigmentosa is a papular pruriginous eruption that leaves a marble-like pigmentation. The majority of cases have been found in japan. Three new female. Sicilian patients with prurigo pigmentosa were studied. All of them had previously been diagnosed as having different types of dermatitis. The administration of minocycline, at a dosage of 100 mg/day for 1 month, induced the disappearance of the papular eruption and pruritus in two patients, with an improvement of the gross reticular pigmentation. The third showed no modifications of the clinical picture after 2 months of minocycline treatment, but her condition significantly improved after 1 month of treatment with diaminodiphenylsulfone, 100 mg/day. These observations allow us to suggest that prurigo pigmentosa might be relatively frequent but misdiagnosed in the Sicilian population.- - - - - - - - - - ranking = 1keywords = pigmentosa (Clic here for more details about this article) |
2/23. The successful treatment of prurigo pigmentosa with macrolide antibiotics.Recent studies have demonstrated that macrolide antibiotics have anti-inflammatory as well as antibacterial effects. Therefore, macrolide antibiotics have been successfully used to treat patients with various inflammatory diseases. We evaluated the effect of macrolide antibiotics in 4 patients with prurigo pigmentosa who were treated with either 400 mg of clarithromycin or 300 mg of roxythromycin daily. Eruption and pruritus disappeared within a week in all the patients while those symptoms were unresponsive to other drugs. Although the mechanism of this effect remains unclear in patients with prurigo pigmentosa, macrolide antibiotics can be considered as an alternative treatment for prurigo pigmentosa.- - - - - - - - - - ranking = 1keywords = pigmentosa (Clic here for more details about this article) |
3/23. prurigo pigmentosa from contact allergy to chrome in detergent.prurigo pigmentosa is a recurrent inflammatory dermatosis characterized by pruritic erythematous papules and reticulate hyperpigmentation that occurs most frequently in spring and summer. The etiology of prurigo pigmentosa remains unknown. Numerous authors have suggested that various contact allergens may be pathogenic or triggering factors, but nearly all attempts to identify an allergen have been unsuccessful. We report a case of prurigo pigmentosa induced by contact allergy to chrome in detergent, supporting the conclusion that contact allergens such as chrome may play a role in inducing prurigo pigmentosa.- - - - - - - - - - ranking = 1.1428571428571keywords = pigmentosa (Clic here for more details about this article) |
4/23. Vesicular prurigo pigmentosa cured by minocycline.We present a case of prurigo pigmentosa associated with vesicles that we call 'vesicular prurigo pigmentosa'. The subject was treated using minocycline with good results and no recurrence of the lesions over a 2-year period.- - - - - - - - - - ranking = 0.85714285714286keywords = pigmentosa (Clic here for more details about this article) |
5/23. prurigo pigmentosa.BACKGROUND: prurigo pigmentosa is a rare inflammatory dermatosis of unknown etiology characterized by recurrent, pruritic erythematous papules and gross reticulate hyperpigmentation. It is seen most commonly among young adult Japanese females. Only 20 cases have been described outside japan. methods: We report two female, Turkish patients aged 20 and 26 years who had a pruritic rash with the characteristic clinical appearance and supportive histopathology of prurigo pigmentosa. RESULTS: They were successfully treated with minocycline and doxycycline. CONCLUSIONS: prurigo pigmentosa is a relatively new clinical entity, and we believe that a more widespread knowledge of this disease will lessen its misdiagnosis. We find it noteworthy to point out that there may be a predisposition to prurigo pigmentosa amongst the Turkish and Sicilian populations.- - - - - - - - - - ranking = 1.1428571428571keywords = pigmentosa (Clic here for more details about this article) |
6/23. prurigo pigmentosa in a patient with primary biliary cirrhosis and Sjogren syndrome.A 44-year-old Japanese woman suddenly developed severely pruritic erythematous papules on her trunk in a symmetrical distribution. biopsy specimens showed the typical histopathological findings of prurigo pigmentosa. She had had recurrent episodes of high fever spikes for several years, and lost 10 kg in the last year. She was diagnosed as primary biliary cirrhosis (PBC) associated with subclinical Sjogren syndrome (SjS). Predonisolone (60 mg/day) for two weeks was effective for the PBC and fever, but not for the prurigo pigmentosa. PBC may be involved in the pathogenesis of this rare skin disease.- - - - - - - - - - ranking = 0.85714285714286keywords = pigmentosa (Clic here for more details about this article) |
7/23. Vesiculous prurigo pigmentosa in a 13-year-old girl: good response to isotretinoin.prurigo pigmentosa is a rare inflammatory disease of unknown origin, first reported from japan, with only 33 cases described in non-Japanese patients. We describe a 13-year-old girl with a pruriginous symmetrical eruption of papules and vesicles affecting her back, neck and chest of 1 month duration. She remembered a similar, but lighter eruption, 2 months before. As the initial diagnosis was of a vesiculobullous form of darier disease, treatment with isotretinoin 40 mg/day was started with good response. Histological study showed a superficial perivascular and interstitial dermatitis composed predominantly of lymphocytes. The epidermis was spongiotic, with exocytosis of lymphocytes and some neutrophils and necrotic keratinocytes. All these findings were consistent with prurigo pigmentosa. The lesions resolved leaving a light brown reticulate hyperpigmentation. prurigo pigmentosa has never been reported in prepubescent patients, the vesiculobullous forms are unusual, and the only treatments used previously are sulphonamides, tetracyclines and macrolides. We report a 13-year-old Caucasian girl with vesiculobullous prurigo pigmentosa successfully treated with isotretinoin.- - - - - - - - - - ranking = 1.1428571428571keywords = pigmentosa (Clic here for more details about this article) |
8/23. Adult-onset Still's disease with prurigo pigmentosa-like skin eruption.A 34-year-old woman with adult-onset Still's disease (AOSD) developed prurigo pigmentosa-like lesions on her chest and upper back in addition to the typical rash of AOSD. A biopsy specimen taken from the upper back showed characteristic features of prurigo pigmentosa. The eruption and fever subsided immediately after the administration of 40 mg/day prednisolone, but arthralgia persisted even after intravenous pulse methylprednisolone therapy in combination with immunosuppressive drugs. Various atypical skin rashes, including prurigo pigmentosa-like lesions, have been reported in association with AOSD. Therefore, one should carefully follow the clinical course of a patient in order not to overlook these atypical cutaneous manifestations of AOSD.- - - - - - - - - - ranking = 1keywords = pigmentosa (Clic here for more details about this article) |
9/23. Bullous prurigo pigmentosa.prurigo pigmentosa is a rare inflammatory skin disease of unknown etiology, characterized by recurrent, symmetrical, pruritic, erythematous papules resulting in gross reticular hyperpigmentation. The rash occurs mainly on the back, the chest and the nape of the neck. While PP is observed rather frequently in japan, only a few cases have come to notice in other countries. Vesicular or bullous forms have been reported only rarely. The differential diagnosis includes lichen pigmentosus, pigmented contact dermatitis, confluent and reticulated papillomatosis of Gougerot and Carteaud, dermatitis herpetiformis and bullous lichen ruber planus.This case report concerns a young Caucasian patient with prurigo pigmentosa, in whom predominantly vesicular, but also bullous manifestations appeared on an existing maculopapular eruption on the trunk.- - - - - - - - - - ranking = 0.85714285714286keywords = pigmentosa (Clic here for more details about this article) |
10/23. prurigo pigmentosa treated with doxycycline.prurigo pigmentosa is characterized by an inflammatory phase with pruritic erythematous papules and a resolution phase with reticulated pigmentation. It is not a well known entity except in japan. We present a Turkish young man with prurigo pigmentosa treated with doxycycline.- - - - - - - - - - ranking = 0.85714285714286keywords = pigmentosa (Clic here for more details about this article) |
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