1/3. Papular acantholytic dyskeratosis of the vulva.We describe two patients with unusual asymptomatic, papular lesions on the vulva, clinically resembling lichen planus, the histology of which revealed unexpected findings of suprabasilar clefting, acantholysis and dyskeratotic cells giving rise to corps ronds and grains together with hyperkeratosis and parakeratosis, features originally associated with a diagnosis of Darier's disease. Focal acantholytic dyskeratosis has been described in a wide variety of inflammatory and neoplastic processes including those involving mucous membranes and has been attributed various diagnostic labels. We feel that the findings in our patients are consistent with a diagnosis of papular acantholytic dyskeratosis of the vulva, a rare condition, which was first described in 1984.- - - - - - - - - - ranking = 1keywords = lichen (Clic here for more details about this article) |
2/3. Childhood anogenital lichen sclerosus. A case report.Childhood lichen sclerosus is a rare disorder. A 4-year-old girl with chronic vulvar pruritus who was initially suspected to be the victim of child abuse was treated. Vulvar biopsy was performed, confirming the diagnosis of lichen sclerosus. The child was treated with 2% progesterone cream, with complete resolution of her pruritic symptoms and signs of traumatic injury to the vulvar skin. The basic condition, lichen sclerosus, has persisted.- - - - - - - - - - ranking = 336.06453703873keywords = lichen sclerosus, sclerosus, lichen (Clic here for more details about this article) |
3/3. Treatment of lichen sclerosus with potassium para-aminobenzoate.In five patients with symptomatic lichen sclerosus, significant clinical improvement was obtained following the administration of potassium para-aminobenzoate. Improvement was characterized by a marked decrease or absence of symptoms and a flattening of skin lesions.- - - - - - - - - - ranking = 240.04609788481keywords = lichen sclerosus, sclerosus, lichen (Clic here for more details about this article) |