1/56. Chronic sternal wound infection and endocarditis with coxiella burnetii.Chronic q fever is most commonly associated with culture-negative endocarditis and less frequently with infection of vascular grafts, infection of aneurysms, hepatitis, pulmonary disease, osteomyelitis, and neurological abnormalities. We report a case of chronic sternal wound infection, polyclonal gammopathy, and mixed cryoglobulinemia in which q fever endocarditis was subsequently diagnosed. polymerase chain reaction analysis of the wound tissue was positive for Coxiella burnetii dna, and treatment of the endocarditis resulted in prompt healing of the wound. Chronic q fever can occur without epidemiological risk factors for C. burnetii exposure and can produce multisystem inflammatory dysfunction, aberrations of the immune system, and persistent wound infections.- - - - - - - - - - ranking = 1keywords = q (Clic here for more details about this article) |
2/56. livedo reticularis revealing a latent infective endocarditis due to Coxiella burnetti.We report the first case of livedo reticularis revealing a latent infective endocarditis due to Coxiella burnetti. The patient, a 54-year-old woman, also had chronic thrombocytopenia and mixed cryoglobulinemia. Chronic q fever was confirmed by serodiagnosis and livedo regressed totally with doxycycline and hydroxychloroquine.- - - - - - - - - - ranking = 0.5keywords = q (Clic here for more details about this article) |
3/56. A case of q fever acquired in sweden and isolation of the probable ethiological agent, coxiella burnetii from an indigenous source.Serologically verified indigenous q fever is described in a 52-y-old male, who presented with persistent fever, muscle and joint pain, headache and non-purulent cough. Institution of doxycycline resulted in prompt recovery. coxiella burnetii was isolated from mouldy hay in a barn. The strain differs from previously isolated ones in sweden.- - - - - - - - - - ranking = 2keywords = q (Clic here for more details about this article) |
4/56. Acute q fever: a cause of fatal hepatitis in an Icelandic traveller.Domestic q fever is rare in the Nordic countries; the infection is acquired abroad in the majority of cases. This is the first Nordic report of a fatal case of q fever, which occurred in an Icelandic cancer patient who had travelled to the Canary islands.- - - - - - - - - - ranking = 0.5keywords = q (Clic here for more details about this article) |
5/56. Sexually transmitted q fever.We report the sexual transmission of coxiella burnetii from a man with occupationally acquired q fever to his wife. Fifteen days after coitus, his wife also developed serologically proven acute q fever. C. burnetii dna sequences were detected by polymerase chain reaction (PCR) performed on semen samples obtained from the husband at 4 and 15 months after the onset of acute q fever, but PCR results were variable at 23 months, indicating the presence of few organisms.- - - - - - - - - - ranking = 1keywords = q (Clic here for more details about this article) |
6/56. doxycycline and chloroquine as treatment for chronic q fever endocarditis.endocarditis is a rare but severe complication of q fever, an infectious disease caused by the intracellular pathogen coxiella burnetii. heart involvement is the most common clinical presentation of chronic q fever, and it occurs almost invariably in patients with previous valvular disease or artificial valves, and in the immunocompromised host. The optimal treatment of q fever endocarditis is still today debated, and recommended duration of treatment varies from one year to one's lifespan. A case of chronic q fever endocarditis is described in a patient with biological prosthetic aortic valve and aortic homograft, successfully treated with doxycycline and chloroquine for 2 years.- - - - - - - - - - ranking = 2.5keywords = q (Clic here for more details about this article) |
7/56. Acute q fever pericarditis followed by chronic hepatitis in a two-year-old girl.Acute coxiella burnetii infection is most commonly a mild and self-limiting disease with fever, pneumonia and hepatitis. endocarditis is the most frequent clinical presentation of chronic infection. We report a 2-year-old child with q fever who presented with acute pericarditis and cardiac tamponade and who developed a chronic hepatic infection.- - - - - - - - - - ranking = 0.5keywords = q (Clic here for more details about this article) |
8/56. q fever--california, georgia, pennsylvania, and tennessee, 2000-2001.q fever is a zoonotic disease caused by the bacterium coxiella burnetii. The most common reservoirs are domesticated ruminants, primarily cattle, sheep, and goats. humans acquire q fever typically by inhaling aerosols or contaminated dusts derived from infected animals or animal products. Its highly infectious nature and aerosol route of transmission make C. burnetii a possible agent of bioterrorism. Although up to 60% of initial infections are asymptomatic, acute disease can manifest as a relatively mild, self-limited febrile illness, or more moderately severe disease characterized by hepatitis or pneumonia. It manifests less commonly as myocarditis, pericarditis, and meningoencephalitis. Chronic q fever occurs in <1% of infected patients, months or years after initial infection. chronic disease manifests most commonly as a culture-negative endocarditis in patients with valvular heart disease. During 2000-2001, a total of 48 patients who met the case definition of q fever were reported to CDC. This report describes the case investigations for six of these patients, which indicate that these persons acquired q fever probably through direct or indirect contact with livestock. To enhance surveillance efforts, health-care providers should report cases of q fever to state health departments.- - - - - - - - - - ranking = 1keywords = q (Clic here for more details about this article) |
9/56. Mononeuritis multiplex caused by coxiella burnetii infection (q fever).After 1 week of flu-like illness, a 64-year-old man developed rapidly progressive mononeuritis multiplex involving the right arm and both legs. Serologic studies identified coxiella burnetii as the cause of the febrile disease (q fever). Fourteen days doxycycline treatment (200 mg daily) induced rapid and complete recovery. After 6 months, flu-like symptoms, weakness and hypalgesia of the right leg reappeared. Antibody titers again identified q fever. doxycycline was re-established and induced prompt recovery. q fever has been associated with various neurologic complications such as meningoencephalitis, cerebellitis, optic neuritis or polyneuroradiculitis. This is the first report on q fever related mononeuritis multiplex. Prolonged antibiotic treatment may be required to prevent relapsing infection from the resistant bacterium.- - - - - - - - - - ranking = 0.5keywords = q (Clic here for more details about this article) |
10/56. Acute acalculous cholecystitis associated with q fever: report of seven cases and review of the literature.q fever is a worldwide-occurring zoonosis caused by coxiella burnetii. There are various clinical manifestations of acute q fever, of which acute cholecystitis is a very rare clinical presentation. This study reports seven cases of acute cholecystitis associated with coxiella burnetii and reviews two other cases from the literature. All patients were admitted to hospital for fever and abdominal pain in the right upper quadrant. Abdominal echography showed a distended gallbladder with biliary sludge without concrements in eight cases and with a single stone in one case. diagnosis was made by specific serological investigation (microimmunofluorescence assay) for coxiella burnetii. All nine patients were cured, six after laparoscopic cholecystectomy and three with antibiotics only. Histological examination of the gallbladders showed inflammation in five cases, although coxiella burnetii was not detected by immunohistochemistry. The results show that laboratory investigations in patients admitted to hospital for symptoms consistent with acute acalculous cholecystitis should include a systematic search for coxiella burnetii.- - - - - - - - - - ranking = 0.5keywords = q (Clic here for more details about this article) |
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