1/3. Linear pemphigus vulgaris after X-ray irradiation.The authors report the case of a 64-year-old female with a pemphigus vulgaris that relapsed on her left cheek following X-irradiation. The lesion developed not only on the irradiated area but also along a linear streak. Blaschko lines seem to represent the linear systematization pattern more likely to account for this unusual distribution.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
2/3. pemphigus vulgaris following cobalt therapy for bronchial carcinoma.A 52-year-old male patient with bronchial carcinoma developed pemphigus vulgaris 3 weeks after the end of cobalt therapy. The possible role of gamma-radiation in inducing the skin disease is discussed.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
3/3. Paraneoplastic pemphigus appearing as bullous pemphigoid-like eruption after palliative radiation therapy.Paraneoplastic pemphigus is a recently described disease in which patients have polymorphous skin lesions suggestive of both erythema multiforme major and pemphigus vulgaris in association with internal neoplasms, especially non-Hodgkin's lymphoma. These patients have characteristic autoantibodies that bind specific epidermal proteins. A Nikolsky-negative bullous pemphigoid-like eruption developed within the radiation therapy field in a 72-year-old man receiving palliative treatment for recurrent large cell lymphoma. The eruption rapidly progressed to a Nikolsky-positive bullous process more typical of pemphigus vulgaris with extensive involvement of respiratory epithelia. Despite aggressive treatment with high-dose corticosteroids and antibiotics, the patient rapidly succumbed. Results of immunofluorescence studies and autopsy findings confirmed the diagnosis of paraneoplastic pemphigus.- - - - - - - - - - ranking = 0.4keywords = vulgaris (Clic here for more details about this article) |