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1/9. Long-term posterior and anterior segment complications of immune recovery uveitis associated with cytomegalovirus retinitis.

    PURPOSE: To identify and describe long-term posterior and anterior segment complications of immune recovery uveitis in patients with inactive cytomegalovirus retinitis who are undergoing highly active antiretroviral therapy-mediated recovery of immune function.methods: A prospective cohort study at a university medical center. Twenty-nine eyes of 21 patients with immune recovery uveitis and inactive cytomegalovirus retinitis were followed for 14.5 to 116 weeks (median, 43 weeks) after diagnosis of immune recovery uveitis. RESULTS: Nine eyes of nine patients developed visually important complications involving the posterior segment, anterior segment, or a combination of both. Posterior segment complications included severe proliferative vitreoretinopathy in three eyes and spontaneous vitreous hemorrhage from avulsion of a blood vessel secondary to contraction of the inflamed vitreous in one eye. Proliferative vitreoretinopathy recurred in all cases after surgery, severely compromising the visual outcome. Anterior segment complications included posterior subcapsular cataracts with vision decrease in five eyes and persistent anterior chamber inflammation after cataract extraction, resulting in posterior synechiae and large visually important lens deposits in three eyes.CONCLUSION: Persistent inflammation in immune recovery uveitis may lead to vision-threatening complications, such as proliferative vitreoretinopathy, posterior subcapsular cataracts, and severe postoperative inflammation. Immune recovery uveitis is a chronic inflammatory syndrome that may result in complications months to years after the onset of inflammation.
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2/9. Laser photocoagulation repair of recurrent macula-sparing retinal detachments.

    Laser photocoagulation was performed around a detached retina in 4 patients who developed localized retinal detachment after successful scleral buckling. The range of retinal redetachment in all 4 patients was no larger than that of the initial retinal detachment and did not go over the vascular arcade. No evidence of vitreous traction or proliferative vitreoretinopathy was observed in these cases. Laser photocoagulation was performed in 3 lines of gray-white burn around the detached retina. Retinal attachment occurred between 4 and 14 days of laser treatment in all cases. No procedure related complications were seen. Laser photocoagulation may be an alternative procedure for the treatment of redetached retina with little and shallow detachment, before considering resurgery.
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3/9. Idiopathic cyclitic retrolental membrane in children.

    BACKGROUND: Cyclitic retrolental membranes (CRM) in children are usually associated with chronic uveitis or genetic syndromes. We report two rare cases of idiopathic CRM. patients AND methods: Two girls aged 9 and 13 years with visual acuities (VA) of 0.05 underwent lensectomy and anterior vitrectomy with dissection of the central part of the retrolental membrane and intraocular lens (IOL) implantation. RESULTS: The clinical evolution was excellent for the 9 year old girl who recovered 1.0 VA after 2 months. Histological examination revealed a fibroelastic tissue of unknown origin without inflammatory components. The 13 year old girl showed VA of 0.6 within 1 month. However, a recurrent CRM developed with retinal detachment and proliferative vitreoretinopathy (PVR). vitrectomy, complete excision of the CRM and 360 degrees retinotomy with silicon oil tamponade attached the retina with limited visual recovery. histology showed fibrovascular tissue with inflammatory components infiltrating the CRM. CONCLUSIONS: Idiopathic CRM in children are rare and can be composed of different histological tissues with very different clinical outcomes.
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4/9. Extensive peripheral retinectomy combined with posterior 360 degrees retinotomy for retinal reattachment in advanced proliferative vitreoretinopathy cases.

    Posterior 360 degrees retinotomy in conjunction with extensive peripheral retinectomy was necessary for retinal reattachment in 18 eyes. A visual acuity of 20/400 or better was achieved in 22% of the patients; in patients with rubeosis, regression was found in 89%. Of the hypotonus eyes, preoperatively 78% were normotensive postoperatively after removal of anterior proliferative vitreoretinopathy (PVR) covering ciliary epithelium. The major intraoperative complication was hemorrhage, which could be readily controlled. Recurrent retinal detachment (RD) occurred in 39% and reproliferation in 50% of the patients.
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5/9. Silicone oil particles trapped in the subretinal space: complications after substitution of the vitreous.

    Silicone oil particles trapped in the subretinal space, following total replacement of the vitreous by oil, were found in the aphakic eye of a 51-year-old man. The eye had been operated on two times for retinal detachment in other institutes which resulted in a grade D-1 proliferative vitreoretinopathy. The silicone particles resembled beads and were slightly mobile among subretinal strands by changing the eye position. The particles freely moved into the vitreous cavity through a retinotomy site and were removed with the silicone from the vitreous cavity because of ocular pain. Subconjunctival granulation was removed and histological examination showed silicone oil particles in the vitreous cavity, and cellular infiltration.
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6/9. The question of ocular tolerance to intravitreal liquid silicone. A long-term analysis.

    The authors report a retrospective review of 407 eyes that received intravitreal liquid silicone between 1961 and 1984. Initial anatomical success was noted in 270 eyes (66.3%), while initial functional success was achieved in 103 eyes (25.3%). Ten years postoperatively, approximately half of the eyes with initial functional success still had functional vision (49.2%). These eyes had less advanced proliferative vitreoretinopathy and fewer inferior breaks than others. Recurrent retinal detachment rather than late complications was the predominant cause of functional failure in those eyes losing functional vision in less than ten years postoperatively. Late complications were common and frequently required therapeutic intervention. Intravitreal liquid silicone was of great benefit to many monocular patients, but of little benefit to the binocular patients in our series.
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7/9. Spontaneous reattachment of the retina despite proliferative vitreoretinopathy.

    In six cases of spontaneous retinal reattachment despite severe proliferative vitreoretinopathy, the retina was initially attached after a buckling procedure or vitreous surgery for proliferative vitreoretinopathy. However, each retina suddenly detached several weeks later. Surprisingly, the retinas settled slowly during the following weeks without further treatment. One case was marked by repeated episodes of detachment and reattachment. In none of the cases could an open retinal break be detected. In certain cases of proliferative vitreoretinopathy in which no open break is apparent and the detachment appears to be tractional, an observation period of several weeks may allow the retina to reattach spontaneously without further surgery.
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8/9. Silicone assisted, argon laser confinement of recurrent proliferative vitreoretinopathy related retinal detachment: a technique to allow silicone oil removal in problem eyes.

    AIMS/BACKGROUND: Recurrent peripheral retinal detachments may occur in eyes treated with vitrectomy and silicone oil for retinal detachments complicated by proliferative vitreoretinopathy (PVR). The aim of this study was to assess whether laser photocoagulation could be used in the presence of silicone oil to confine and stabilise recurrent PVR related peripheral retinal detachments enabling the timely removal of the oil. methods: 10 patients with recurrent peripheral retinal detachments after vitrectomy and silicone oil insertion were treated with posturing and subsequent focal argon laser to circumscribe the area of recurrent detachment. RESULTS: This technique alone was sufficient to limit the area of retinal detachment in seven of the cases. The remaining three cases required relieving retinotomies because of increasing retinal detachment despite the laser. In all 10 cases the silicone oil was later removed without progression of the detached areas. CONCLUSION: Silicone assisted argon laser 'confinement' can be effective in stabilising eyes with peripheral retinal detachments allowing the subsequent removal of silicone oil.
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9/9. Neovascular complications associated with rubeosis iridis and peripheral retinal detachment after retinal detachment surgery.

    PURPOSE: To report clinical features and surgical management of neovascular complications associated with rubeosis iridis and peripheral retinal detachment after retinal detachment surgery in nondiabetic patients. methods: Seven consecutive eyes of seven nondiabetic patients who developed neovascular complications associated with rubeosis iridis and peripheral retinal detachment after scleral buckling and vitrectomy procedures were retrospectively reviewed. None of the eyes had clinical evidence of anterior segment ischemia or retinal vascular disease, but each eye developed rubeosis iridis and neovascular complications. RESULTS: Of the seven eyes with rubeosis iridis and peripheral retinal detachment, six developed recurrent or progressive vitreous hemorrhage, and three developed progressive neovascular glaucoma. Four eyes underwent a revision procedure to repair the peripheral retinal detachment, and anterior proliferative vitreoretinopathy was found in each of these cases. Rubeosis iridis regressed in all three eyes in which surgery resulted in complete reattachment of the retina. In one eye with persistent peripheral retinal detachment and in the three remaining eyes that did not undergo revision surgery, rubeosis iridis persisted and was associated with long-term neovascular complications. Final corrected visual acuity was 20/70 to 20/400 in three eyes with total retinal reattachment and no light perception to hand motions in four eyes with persistent peripheral retinal detachment and rubeosis iridis. CONCLUSION: Visually significant neovascular complications may occur in eyes that develop rubeosis iridis associated with peripheral retinal detachment after retinal detachment surgery in nondiabetic patients. Successful repair of the peripheral retinal detachment may induce regression of rubeosis iridis, reduce associated complications, and improve the long-term prognosis of these eyes.
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