1/17. Central retinal vein occlusion during remission of ulcerative colitis.BACKGROUND: Retinal vascular disease is a rare complication of ulcerative colitis. CASE: We report a patient who developed unilateral nonischemic central retinal vein occlusion (CRVO) (papillophlebitis) without any other retinal vascular disease during remission of ulcerative colitis. OBSERVATIONS: The best-corrected visual acuities were 1.5 OD and 0.7 OS. Dilated and tortuous retinal veins and retinal bleeding were seen in the left eye. macular edema and leakage from the papilla and the retinal veins of the left eye were evident on fluorescein angiography. After increased dosage of systemic prednisolone was prescribed, the retinal vascular changes resulting from CRVO (papillophlebitis) in the left eye gradually abated. CONCLUSIONS: Retinal vascular diseases should be monitored during both remission and activation of intestinal symptoms of ulcerative colitis.- - - - - - - - - - ranking = 1keywords = vascular disease (Clic here for more details about this article) |
2/17. Systemic lupus erythematosus presenting earlier as retinal vaso-occlusion.Retinal vascular lesions are the most common ophthalmologic manifestation of systemic lupus erythematosus (SLE), occurring in 3% to 29% of cases, generally late in the disease. More rare is the severe vaso-occlusive disease, often termed "retinal vasculitis", which includes central retinal artery occlusion, multifocal arteriolar occlusions, extensive capillary nonperfusion and central venous occlusion. patients with SLE and raised serum concentrations of anticardiolipin antibodies (ACA) have a higher risk of developing occlusive ocular vascular disease. We report a case in which retinal involvement was an earlier manifestation of SLE in a patient without ACA.- - - - - - - - - - ranking = 0.33333333333333keywords = vascular disease (Clic here for more details about this article) |
3/17. Central retinal vein prethrombosis as an initial manifestation of protein s deficiency.CONTEXT: Retinal vein thrombosis is most common in old people, and is often associated with systemic vascular disease. One of its rare systemic causes is protein s deficiency. CASE REPORT: A case of a 21-year-old woman with retinal vein prethrombosis associated only with protein s deficiency is described. She presented with acutely reduced visual acuity and a central scotoma in her left eye. warfarin therapy was initiated, and complete improvement in ophthalmoscopic findings was subsequently observed. This case illustrates that protein s deficiency is a factor that should be considered in cases of retinal vein occlusion, particularly in young patients.- - - - - - - - - - ranking = 0.33333333333333keywords = vascular disease (Clic here for more details about this article) |
4/17. Central retinal vein occlusion: a prospective histopathologic study of 29 eyes in 28 cases.The clinical and histopathologic features of 29 eyes from 28 patients with central retinal vein occlusion (CRVO) are reported. A fresh or a recanalized thrombus was observed in each eye. This study considers the temporal aspects of the cases, and it notes the different morphologic features of the occlusion. These observations explain most of the variability of the changes observed in previous reports. We believe these different features representthe various stages in the natural evolution of such a thrombus. The interval between CRVO and histopathologic study in our series ranged from six hours to more than ten years. Local and systemic factors were reviewed and were found to be important in the pathogenesis of thrombus formation. Local diseases with a predisposing effect on CRVO included: glaucoma, papilledema, subdural hemorrhage, optic nerve hemorrhage, and drusen of the optic nerve head. Associated systemic diseases included: hypertension, cardiovascular and cerebrovascular disease, diabetes mellitus, and leukemia with thrombocytopenia. A fresh thrombus in the CRVO was observed in three (10.3%), and a recanalized thrombus in 26 eyes (89.7%). Endothelial-cell proliferation was a conspicuous feature in 14 (48.3%) of the eyes. Chronic inflammation in the area of the thrombus and/or vein wall or perivenular area was observed in 14 (48.3%) of the eyes. Arterial occlusive disease was observed in seven eyes (24.6%). Cystoid macular edema was found in 26 (89.7%) of the eyes.- - - - - - - - - - ranking = 0.33333333333333keywords = vascular disease (Clic here for more details about this article) |
5/17. chlamydia conjunctivitis and central retinal vein occlusion.PURPOSE: To report a case of coexistent chlamydia conjunctivitis and central retinal vein occlusion (CRVO) in which both problems improved significantly after oral doxycyline. DESIGN: Interventional case report. methods: A healthy 39-year-old man presented with follicular and papillary conjunctivitis, unresponsive to topical antibiotic therapy, and a CRVO. The patient had serum IgG titers of 1:256 to both chlamydia pneumonia and chlamydia trachomatous. RESULTS: Treatment with oral doxycyline (100 mg orally twice daily for 2 weeks) resulted in complete resolution of the conjunctivitis and rapid improvement of the CRVO. CONCLUSIONS: Because of its ability to cause chronic vascular endothelial infection and localized inflammation, chlamydia has been implicated in the development of arterial vascular disease. The positive chlamydia serology, conjunctivitis, CRVO, and excellent response to doxycycline in this patient suggest that chlamydia may have contributed to his vascular occlusion. Further studies investigating a possible association between chlamydia and CRVO may be indicated.- - - - - - - - - - ranking = 0.33333333333333keywords = vascular disease (Clic here for more details about this article) |
6/17. Combined branch retinal artery and central retinal vein obstruction.We observed seven patients with the unusual combination of a central retinal vein obstruction in conjunction with a simultaneous branch retinal artery obstruction. The patients presented with sectoral retinal whitening, as well as diffuse peripapillary and superficial retinal hemorrhages. In five of the seven patients, the retinal hemorrhages appeared most florid in the territory of the obstructed arteriole, resulting initially in the consideration that these cases represented a combined branch retinal artery and branch retinal vein obstruction. In all cases, however, the presence of dilated, tortuous veins with diffuse retinal hemorrhages, in addition to generalized delay in arteriovenous transit on fluorescein angiography, localized the venous blockage to the central retinal vein. No intra-arterial retinal emboli were visualized. Initially, five of the seven patients suffered markedly diminished visual function; although visual acuity returned to near normal in all but two patients. In the two patients with non-resolving, markedly impaired visual acuity, neovascularization of the iris complicated the clinical course. Both of these patients were treated with panretinal photocoagulation, with resolution of the iris neovascularization. These seven patients highlight another variation of combined arterial and venous retinal vascular disease.- - - - - - - - - - ranking = 0.33333333333333keywords = vascular disease (Clic here for more details about this article) |
7/17. Vaso-occlusive retinopathy in the primary anti-phospholipid antibody syndrome.We report two patients with contrasting patterns of retinal vascular occlusion associated with the primary anti-phospholipid antibody syndrome. The immuno-pathological features and clinical associations are discussed. This condition is of interest to ophthalmologists because of its association with thrombosis in the eye, brain and elsewhere and because it provides new insights into the pathogenesis of retinal vascular disease in young patients.- - - - - - - - - - ranking = 0.33333333333333keywords = vascular disease (Clic here for more details about this article) |
8/17. Central retinal vein occlusion in a young patient with seropositive syphilis.Central retinal vein occlusion (CRVO) is a common retinal vasculopathy typically affecting adults in the fifth to seventh decade of life. Systemic disease, particularly hypertension, is often a contributing factor in this sight-threatening condition. CRVO in young adults, however, is an uncommon occurrence with relatively few reported cases in the ophthalmic literature. Two studies performed on young adults (less than 40 years of age) presenting with CRVO revealed that, in most cases, there was not a strong correlation with hypertension or other systemic diseases. In more severe cases, namely those with poor visual outcome from the ischemic type of CRVO, there was a strong correlation with cardiovascular disease and diabetes mellitus. Systemic inflammatory conditions represent a small contributing factor in patients presenting with CRVO. This paper reports on a 21-year-old female with non-ischemic CRVO who was serologically positive for syphilis.- - - - - - - - - - ranking = 0.33333333333333keywords = vascular disease (Clic here for more details about this article) |
9/17. Retinal and choroidal vaso-occlusive disease in systemic lupus erythematosus associated with antiphospholipid antibodies.Three patients with systemic lupus erythematosus (SLE) associated with anti-phospholipid antibodies are reported. All three had severe vaso-occlusive disease: the first had an unilateral vaso-occlusive retinopathy, the second an unilateral central retinal venous obstruction, and the third a bilateral ischemic choroidopathy. The association of these occlusive ocular vascular diseases with the presence of the lupus anticoagulant and other associated factors in SLE is discussed.- - - - - - - - - - ranking = 0.33333333333333keywords = vascular disease (Clic here for more details about this article) |
10/17. Crohn's disease and retinal vascular disease.patients with Crohn's disease may manifest extraintestinal findings including ocular involvement. We treated two patients with Crohn's disease who manifested retinal vascular disease that may have been related to the immune nature of the underlying disease or possibly to changes in the vasculature or coagulation system. One patient had a central retinal vein occlusion and the other had retinal vasculitis involving retinal arteries and veins with an apparent branch retinal artery occlusion. Both patients were in excellent health except for Crohn's disease, which was confirmed by a biopsy specimen. In one patient, the diagnosis of retinal vasculitis preceded the clinical diagnosis of Crohn's disease, whereas for the second patient the symptomatology of the intestinal disease preceded the ocular manifestations. We suggest that inflammatory bowel disease should be considered in the differential diagnosis of retinal vascular occlusive disease, especially in a young patient.- - - - - - - - - - ranking = 1.6666666666667keywords = vascular disease (Clic here for more details about this article) |
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