1/11. Cutaneous aspects of down syndrome.down syndrome is associated with an increased incidence of cutaneous manifestations such as atopic dermatitis, alopecia areata, elastosis perforans serpiginosa, syringomas, and skin infections. We describe 3 patients with down syndrome: an 8-year-old boy with alopecia areata, a 17-year-old boy with crusted scabies, and a 39-year-old woman with a cutaneous collagen vascular disease-like disorder. We also review cutaneous signs of this syndrome.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
2/11. A dilemma: bullous-pemphigoid-like eruption in scabies or scabies-induced bullous pemphigoid.Several diseases may be confused with scabies. Atypical manifestations of scabies have previously been reported, including urticaria, contact dermatitis, and dermatitis herpetiformis. There are also reports of scabies mimicking bullous pemphigoid. Here we report a case of scabies in a patient with manifestation similar to bullous pemphigoid. Direct smear of the bullous lesions was performed and was positive for scabies mites. The skin biopsy specimens submitted for light microscopy and direct immunofluorescence study were considered to be compatible with bullous pemphigoid. The patient treated with single dose oral ivermectin and prednisolone. The pruritus subsided and the eruption improved dramatically in 2 weeks.- - - - - - - - - - ranking = 2keywords = dermatitis (Clic here for more details about this article) |
3/11. Crusted scabies: a case report and review of the literature.Crusted (Norwegian) scabies, a highly contagious variant of classical scabies, has traditionally been associated with mentally retarded and physically debilitated patients. Recent reports have increasingly linked scabies with immunosuppression, as in acquired immunodeficiency syndrome (AIDS) and in transplant recipients. Lesions may mimic those of a wide variety of skin diseases. The patient presented is a 41-year old male with signs of systemic illness and atypical dermatitis. This case illustrates the pitfalls in recognition of crusted scabies and the importance of rapid diagnosis. Diagnostic technique and treatment are briefly reviewed.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
4/11. Norwegian scabies in an infant with acquired immunodeficiency syndrome.A 6-month-old infant with acquired immunodeficiency syndrome (AIDS) and typical scabies subsequently developed Norwegian scabies, with deterioration of clinical status. The infestation spread to several health care workers who were in close contact with the patient, despite standard isolation precautions. In the rapidly growing hospitalized pediatric AIDS population, Norwegian scabies should be considered in the differential diagnosis of eczematous or seborrheic dermatitis.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
5/11. Unusual features of scabies complicating human T-lymphotropic virus type III infection.Four cases of "exaggerated scabies" are described in patients who were immunodeficient secondary to human T-lymphotropic virus type III (HTLV-III) infection. As in classical scabies, these patients had a pruritic dermatitis but lacked the usual distribution of the eruption. The rash was initially misdiagnosed in all four patients. scabies should be considered in pruritic dermatitis in patients at risk for HTLV-III infection.- - - - - - - - - - ranking = 2keywords = dermatitis (Clic here for more details about this article) |
6/11. Norwegian-type scabies mimicking contact dermatitis in an immunosuppressed patient.patients taking immunosuppressive drugs are susceptible to various forms of infection, including dermatologic disease. Recently, atypical manifestations of scabies have been reported in such patients. In the case reported here, a 26-year-old woman who had had a renal transplant and was taking immunosuppressive drugs had a pruritic rash on the back that closely resembled contact dermatitis. However, skin scrapings from the involved areas and punch biopsy specimen of the back showed live scabies mites. The pruritus was relieved and the skin lesions disappeared within ten days of treatment with scabicides. We believe that current widespread use of immunosuppressive agents may result in more cases of atypical forms of scabies. Therefore, physicians who deal with immunosuppressed patients should be aware of this possibility.- - - - - - - - - - ranking = 5keywords = dermatitis (Clic here for more details about this article) |
7/11. Host-parasite relationships in hyperkeratotic (Norwegian) scabies: pathological and immunological findings.The dynamics of intraepidermal penetration of the scabies mite and the host's responses to the invaders have been studied in hyperkeratotic scabies. Contrary to the generally accepted view, the mites progressed not only through the stratum corneum but also into the underlying epidermis and even occasionally to the dermo-epidermal interface. Morphological evidence of reactive processes included parakeratosis surrounding the burrows, psoriasiform hyperplasia with increased basal cell labelling indices and exocytosis of mononuclear cells. 3H-thymidine labelling indices of immunocompetent cells of the dermal infiltrate reached levels found in allergic patch test reactions and were in both cases higher than in non-immune-specific inflammatory processes. The labelling index of peripheral blood lymphocytes showed an increased ratio of B cells to T cells as compared to controls or patients with allergic contact dermatitis. serum CIq fixation was higher than in untreated patients with common scabies. These results support our previous findings of immunological activation in host infested by the scabies mite.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
8/11. Crusted (Norwegian) scabies in patients with AIDS: the range of clinical presentations.Crusted (Norwegian) scabies in AIDS patients can be manifested in both typical and atypical forms. Although the classic, hyperkeratotic, nonpruritic lesions are most common, reported cases have ranged in spectrum from crusting with pruritus to a pruritic, papular dermatitis to those resembling Darier's disease or psoriasis. We report two additional cases of crusted scabies in AIDS patients, one with typical crusted, hyperkeratotic though pruritic lesions and one with severe pruritis and rare papules, initially misdiagnosed as "pruritus of AIDS." Because of the extremely contagious nature of crusted scabies, as well as its potential for complete cure with appropriate therapy, a high degree of suspicion for this disorder should be maintained in AIDS patients, even when the lesions do not have the classical appearance. The discovery of crusted scabies, whether in its common or its atypical form should prompt testing for the human immunodeficiency virus (hiv).- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
9/11. scabies of the scalp mimicking seborrheic dermatitis in immunocompromised patients.Two children with acute lymphoblastic leukemia undergoing chemotherapy had a special form of scabies characterized by fine scaling of the scalp simulating seborrheic dermatitis. pruritus was mild or absent. Immunocompromised children and adults should receive whole-body and scalp antiscabietic treatment.- - - - - - - - - - ranking = 5keywords = dermatitis (Clic here for more details about this article) |
10/11. Transcutaneous gamma benzene hexachloride absorption and toxicity in infants and children.A premature, malnourished infant had seizures and abnormal neurological function associated with topical gamma benzene hexachloride (lindane) therapy. The level of gamma benzene hexachloride in his blood was 17 times greater than expected after a single topical application of 1% gamma benzene hexachloride. Significant levels developed in another child's blood after repeated applications of small amounts to areas of dermatitis and excoriations on the skin. The use of topical gamma benzene hexachloride in pediatric patients is reviewed because of increased evidence of unpredictable absorption and toxicity.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
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